Results overview: Found 13 records in 0.01 seconds.
Articles, 12 records found
Research literature, 1 records found
Articles 12 records found  1 - 10next  jump to record:
1.
9 p, 1.2 MB The mRNA-1273 Vaccine Induces Cross-Variant Antibody Responses to SARS-CoV-2 With Distinct Profiles in Individuals With or Without Pre-Existing Immunity / Tejedor Vaquero, Sonia (Institut Hospital del Mar d'Investigacions Mèdiques) ; de Campos-Mata, Leire (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramada, José María (CIBER de Epidemiología Y Salud Pública) ; Díaz, Pilar (Institut Hospital del Mar d'Investigacions Mèdiques) ; Navarro-Barriuso, Juan (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ribas-Llaurado, Clara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodrigo Melero, Natalia (Centre de Regulació Genòmica) ; Carolis, Carlo (Universitat Pompeu Fabra) ; Cerutti, Andrea (Institució Catalana de Recerca i Estudis Avançats) ; Gimeno Martínez, Ramón (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Magri, Giuliana (Institut Hospital del Mar d'Investigacions Mèdiques)
mRNA-based vaccines effectively induce protective neutralizing antibodies against SARS-CoV-2, the etiological agent of COVID-19. Yet, the kinetics and compositional patterns of vaccine-induced antibody responses to the original strain and emerging variants of concern remain largely unknown. [...]
2021 - 10.3389/fimmu.2021.737083
Frontiers in immunology, Vol. 12 (September 2021) , art. 737083  
2.
794.3 KB Searching for the Transcriptomic Signature of Immune Tolerance Induction-Biomarkers of Safety and Functionality for Tolerogenic Dendritic Cells and Regulatory Macrophages / Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The last years have witnessed a breakthrough in the development of cell-based tolerance-inducing cell therapies for the treatment of autoimmune diseases and solid-organ transplantation. Indeed, the use of tolerogenic dendritic cells (tolDC) and regulatory macrophages (Mreg) is currently being tested in Phase I and Phase II clinical trials worldwide, with the aim of finding an effective therapy able to abrogate the inflammatory processes causing these pathologies without compromising the protective immunity of the patients. [...]
2018 - 10.3389/fimmu.2018.02062
Frontiers in immunology, Vol. 9 (september 2018)  
3.
13 p, 3.3 MB Comparative transcriptomic profile of tolerogenic dendritic cells differentiated with vitamin D3, dexamethasone and rapamycin / Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Naranjo-Gómez, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sánchez, Alex (Universitat de Barcelona. Departament d'Estadística) ; Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Tolerogenic dendritic cell (tolDC)-based therapies have become a promising approach for the treatment of autoimmune diseases by their potential ability to restore immune tolerance in an antigen-specific manner. [...]
2018 - 10.1038/s41598-018-33248-7
Scientific reports, Vol. 8 (october 2018)  
4.
14 p, 1.3 MB Vitamin D3-Induced Tolerogenic Dendritic Cells Modulate the Transcriptomic Profile of T CD4 + Cells Towards a Functional Hyporesponsiveness / Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez-Cáceres, Eva M. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The use of autologous tolerogenic dendritic cells (tolDC) has become a promising alternative for the treatment of autoimmune diseases. Among the different strategies available, the use of vitamin D3 for the generation of tolDC (vitD3-tolDC) constitutes one of the most robust approaches due to their immune regulatory properties, which are currently being tested in clinical trials. [...]
2021 - 10.3389/fimmu.2020.599623
Frontiers in immunology, Vol. 11 (january 2021)  
5.
11 p, 2.0 MB Optimal response to dimethyl fumarate is mediated by a reduction of Th1-like Th17 cells after 3 months of treatment / Mansilla Lopez, Maria Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Presas-Rodríguez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Teniente Serra, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Quirant, Bibiana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ramo-Tello, Cristina (Universitat Autònoma de Barcelona. Departament de Medicina) ; Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Dimethyl fumarate (DMF) is one of the most promising therapies for relapsing-remitting multiple sclerosis (RRMS) patients since it has shown immunomodulatory and neuroprotective effects. However, a percentage of RRMS patients do not exhibit an optimal response to DMF. [...]
2019 - 10.1111/cns.13142
CNS neuroscience & therapeutics, Vol. 25 (2019) , p. 995-1005  
6.
11 p, 2.0 MB Ethyl Pyruvate Induces Tolerogenic Dendritic Cells / Djedovic, Neda (University of Belgrade. Department of Immunology) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Jevtić, Bojan (University of Belgrade. Department of Immunology) ; Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Saksida, Tamara (University of Belgrade. Department of Immunology) ; Martínez-Cáceres, Eva M. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Miljković, Ðorđe (University of Belgrade. Department of Immunology)
Dendritic cells (DC) are professional antigen presenting cells that have a key role in shaping the immune response. Tolerogenic DC (tolDC) have immuno-regulatory properties and they are a promising prospective therapy for multiple sclerosis and other autoimmune diseases. [...]
2019 - 10.3389/fimmu.2019.00157
Frontiers in immunology, Vol. 10 (February 2019) , art. 157  
7.
14 p, 1.9 MB MAP7 and MUCL1 are biomarkers of Vitamin D3-induced tolerogenic dendritic cells in multiple sclerosis patients / Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ardiaca-Martínez, Alicia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Presas-Rodríguez, Silvia (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ten Brinke, Anja (Amsterdam UMC. University Medical Center) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The administration of autologous tolerogenic dendritic cells (tolDC) has become a promising alternative for the treatment of autoimmune diseases, such as multiple sclerosis (MS). Specifically, the use of vitamin D3 for the generation of tolDC (vitD3-tolDC) constitutes one of the most widely studied approaches, as it has evidenced significant immune regulatory properties, both in vitro and in vivo. [...]
2019 - 10.3389/fimmu.2019.01251
Frontiers in immunology, Vol. 10 (June 2019) , art. 1251  
8.
20 p, 3.2 MB Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA / Derdelinckx, Judith (University Hospital Antwerp (Bèlgica)) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; De Laere, Maxime (University of Antwerp. Laboratory of Experimental Hematology) ; Lee, Wai-Ping (University Hospital Antwerp (Bèlgica)) ; Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Wens, Inez (University of Antwerp. Laboratory of Experimental Hematology) ; Nkansah, Irene (University of Antwerp. Laboratory of Experimental Hematology) ; Daans, Jasmijn (University of Antwerp. Laboratory of Experimental Hematology) ; De Reu, Hans (University of Antwerp. Laboratory of Experimental Hematology) ; Jolanta Keliris, Aneta (University of Antwerp. Bio-Imaging Lab) ; Van Audekerke, Johan (University of Antwerp. Bio-Imaging Lab) ; Vanreusel, Verdi (University of Antwerp. Bio-Imaging Lab) ; Pieters, Zoë (University of Antwerp. Laboratory of Experimental Hematology) ; Van Der Linden, Annemie (University of Antwerp. Bio-Imaging Lab) ; Verhoye, Maraleen (University of Antwerp. Bio-Imaging Lab) ; Molenberghs, Geert (L-BioStat. I-BioStat. KU Leuven) ; Hens, Niel (University of Antwerp. Centre for Health Economics Research and Modelling Infectious Diseases) ; Goossens, Herman (University of Antwerp. Laboratory of Medical Microbiology) ; Willekens, Barbara (University Hospital Antwerp (Bèlgica)) ; Cras, Patrick (University of Antwerp. Born Bunge Institute) ; Ponsaerts, Peter (University of Antwerp. Laboratory of Experimental Hematology) ; Berneman, Zwi (University Hospital Antwerp (Bèlgica)) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cools, Nathalie (University Hospital Antwerp (Bèlgica))
Background: Although effective in reducing relapse rate and delaying progression, current therapies for multiple sclerosis (MS) do not completely halt disease progression. T cell autoimmunity to myelin antigens is considered one of the main mechanisms driving MS. [...]
2019 - 10.1186/s12974-019-1541-1
Journal of neuroinflammation, Vol. 16 (August 2019) , art. 167  
9.
11 p, 861.1 KB Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS) : A harmonised study protocol for two phase i clinical trials comparing intradermal and intranodal cell administration / Willekens, Barbara (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Presas-Rodríguez, Silvia (Universitat Autònoma de Barcelona. Departament de Medicina) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Derdelinckx, Judith (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Lee, Wai-Ping (University Hospital Antwerp (Bèlgica)) ; Nijs, Griet (University Hospital Antwerp (Bèlgica)) ; De Laere, Maxime (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Wens, Inez (University of Antwerp . Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Cras, Patrick (University Hospital Antwerp (Bèlgica)) ; Parizel, Paul (University Hospital Antwerp (Bèlgica)) ; Van Hecke, Wim (Icometrix NV) ; Ribbens, Annemie (Icometrix NV) ; Billiet, Thibo (Icometrix NV) ; Adams, Geert (C-Clear Partners) ; Couttenye, Marie-Madeleine (University Hospital Antwerp (Bèlgica)) ; Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Lopez-Diaz De Cerio, Ascensión (Clínica Universidad de Navarra) ; Inogés, Susana (Clínica Universidad de Navarra) ; Prosper, Felipe (Clínica Universidad de Navarra. Centro de Investigación Médica Aplicada) ; Kip, Anke (Lygature Utrecht) ; Verheij, Herman (Lygature Utrecht) ; Gross, Catharina C. (University of Munster. Department of Neurology) ; Wiendl, Heinz (University of Munster. Department of Neurology) ; Van Ham, Marieke (University of Amsterdam. Academic Medical Centre-AMC) ; Ten Brinke, Anja (University of Amsterdam. Academic Medical Centre-AMC) ; Barriocanal, Ana María (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Massuet-Vilamajó, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Hens, Niel (University of Antwerp. Centre for Health Economic Research and Modelling Infectious Diseases) ; Berneman, Zwi (University of Antwerp. Center for Cell Therapy and Regenerative Medicine) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cools, Nathalie (University Hospital Antwerp (Bèlgica)) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Introduction Based on the advances in the treatment of multiple sclerosis (MS), currently available disease-modifying treatments (DMT) have positively influenced the disease course of MS. However, the efficacy of DMT is highly variable and increasing treatment efficacy comes with a more severe risk profile. [...]
2019 - 10.1136/bmjopen-2019-030309
BMJ open, Vol. 9, Issue 9 (July 2019) , art. e030309  
10.
10 p, 1.6 MB Th1Th17CM lymphocyte subpopulation as a predictive biomarker of disease activity in multiple sclerosis patients under dimethyl fumarate or fingolimod treatment / Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Presas-Rodriguez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Hervas-Garcia, Jose Vicente (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Brieva Ruiz, Luis (Hospital Arnau de Vilanova (Lleida, Catalunya)) ; Moral-Torres, Ester (Hospital de Sant Joan Despí Moisès Broggi) ; Cano, Antonio (Hospital de Mataró. Consorci Sanitari del Maresme) ; Munteis, Elvira (Hospital del Mar (Barcelona, Catalunya)) ; Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Peripheral blood biomarkers able to predict disease activity in multiple sclerosis (MS) patients have not been identified yet. Here, we analyzed the immune phenotype of T lymphocyte subpopulations in peripheral blood samples from 66 RRMS patients under DMF (n = 22) or fingolimod (n = 44) treatment, by flow cytometry. [...]
2019 - 10.1155/2019/8147803
Mediators of Inflammation, Vol. 2019 (2019) , art. 8147803  

Articles : 12 records found   1 - 10next  jump to record:
Research literature 1 records found  
1.
179 p, 12.3 MB Characterization of biomarkers of the generation and functionality of tolerogenic dendritic cells differentiated with vitamin D3 / Navarro Barriuso, Juan ; Martínez Cáceres, Eva María, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
En els darrers anys s'ha produït un gran avenç en el desenvolupament de teràpies cel·lulars inductores de tolerància per al tractament de malalties autoimmunitàries tals com l'esclerosi múltiple (EM) i altres patologies immunomediades. [...]
En los últimos años se ha producido un gran avance en el desarrollo de terapias celulares inductoras de tolerancia para el tratamiento de enfermedades autoinmunitarias tales como la esclerosis múltiple (EM) y otras patologías inmunomediadas. [...]
The last years have witnessed a breakthrough in the development of tolerance-inducing cell therapies for the treatment of autoimmune diseases, such as multiple sclerosis (MS), as well as other immune-mediated pathologies. [...]

2019  

See also: similar author names
2 Navarro-Barriuso, J.
13 Navarro-Barriuso, Juan
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