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12 p, 471.1 KB Quantification of HER family receptors in breast cancer / Nuciforo, Paolo (Hospital Universitari Vall d'Hebron) ; Radosevic-Robin, Nina (Jean Perrin Comprehensive Cancer Center) ; Ng, Tony (University College London. UCL Cancer Institute) ; Scaltriti, Maurizio (Memorial Sloan Kettering Cancer Center) ; Universitat Autònoma de Barcelona
he clinical success of trastuzumab in breast cancer taught us that appropriate tumor evaluation is mandatory for the correct identification of patients eligible for targeted therapies. Although HER2 protein expression by immunohistochemistry (IHC) and gene amplification by fluorescence in situ hybridization (FISH) assays are routinely used to select patients to receive trastuzumab, both assays only partially predict response to the drug. [...]
2015 - 10.1186/s13058-015-0561-8
Breast cancer research, Vol. 17 (april 2015)  

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