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14 p, 2.0 MB Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bywater, M. J. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Sanij, E. (Department of Pathology. University of Melbourne) ; Cameron, D. P. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Schierding, W. (Liggins Institute. The University of Auckland) ; Brajanovski, N. (Cancer Research Division. Peter MacCallum Cancer Centre) ; Son, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Sornkom, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Hein, N. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Evers, M. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Pearson, R. B. (Department of Biochemistry and Molecular Biology. University of Melbourne) ; McArthur, G. A. (St Vincent's Hospital (Sydney)) ; Ganley, A. R. D. (School of Biological Sciences. The University of Auckland) ; O'Sullivan, J. M. (Liggins Institute. The University of Auckland) ; Hannan, R. D. (School of Biomedical Sciences. University of Queensland) ; Poortinga, G. (St Vincent's Hospital (Sydney)) ; Universitat Autònoma de Barcelona
The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain unclear. [...]
2019 - 10.1038/s42003-019-0284-y
Communications Biology, Vol. 2 Núm. 1 (january 2019) , p. 39  

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