Results overview: Found 4 records in 0.02 seconds.
Articles, 4 records found
Articles 4 records found  
1.
22 p, 3.0 MB Involvement of JNK1 in Neuronal Polarization During Brain Development / Castro-Torres, Rubén D. (Universidad de Guadalajara. Department of Cell and Molecular Biology) ; Busquets, Oriol (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Parcerisas, Antoni (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Verdaguer, Ester (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Olloquequi, Jordi (Universidad Autónoma de Chile) ; Ettcheto, Miren (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Beas-Zarate, Carlos (Universidad de Guadalajara. Department of Cell and Molecular Biology) ; Folch, Jaume (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Camins, Antoni (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Auladell, Carme (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization, starting from the cell division of neural stem cells and ending with their final positioning when migrating and maturing. [...]
2020 - 10.3390/cells9081897
Cells, Vol. 9 (august 2020)  
2.
18 p, 1.4 MB Experimental Models for Aging and their Potential for Novel Drug Discovery / Folch, Jaume (Universitat Rovira i Virgili. Facultat de Medicina i Ciències de la Salut) ; Busquets, Oriol (Universitat Rovira i Virgili. Facultat de Medicina i Ciències de la Salut) ; Ettcheto, Miren (Universitat Rovira i Virgili. Facultat de Medicina i Ciències de la Salut) ; Sánchez-López, Elena (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Pallàs, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Beas-Zarate, Carlos (Departamento de Biologia Celulary Molecular, C.U.C.B.A., Universidad de Guadalajara and Division de Neurociencias, Sierra Mojada 800, Col. Independencia, Guadalajara, Jalisco 44340, Mexico.) ; Marin, Miguel (Centro de Biotecnologia. Universidad Nacional de Loja, Av. Pío Jaramillo Alvarado y Reinaldo Espinosa, La Argelia. Loja, Ecuador.) ; Casadesus, Gemma (Department of Biological Sciences, Kent State University, Kent, OH, United States.) ; Olloquequi, Jordi (Universidad Autonoma de Chile. Facultad de Ciencias de la Salud) ; Auladell, Carme (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Camins, Antoni (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica)
An interesting area of scientific research is the development of potential antiaging drugs. In order to pursue this goal, it is necessary to gather the specific knowledge about the adequate preclinical models that are available to evaluate the beneficial effects of new potential drugs. [...]
2018 - 10.2174/1570159X15666170707155345
Current neuropharmacology, Vol. 16 (december 2018) , p. 1466-1483  
3.
13 p, 1.3 MB Amerindian Ancestry Influences Genetic Susceptibility to Chronic Obstructive Pulmonary Disease / Díaz-Peña, Roberto (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Boekstegers, Felix (Statistical Genetics Group, Institute of Medical Biometry and Informatics, University of Heidelberg) ; Silva, Rafael S. (Unidad Respiratorio, Centro de Diagnóstico Terapéutico, Hospital Regional de Talca) ; Jaime, Sergio (Unidad Respiratorio, Centro de Diagnóstico Terapéutico, Hospital Regional de Talca) ; Hosgood, H. Dean (Department of Epidemiology and Population Health, Albert Einstein College of Medicine) ; Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Agustí, Àlvar (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lorenzo Bermejo, Justo (Statistical Genetics Group, Institute of Medical Biometry and Informatics, University of Heidelberg) ; Olloquequi, Jordi (Universidad Autónoma de Chile. Instituto de Ciencias Biomédicas) ; Universitat Autònoma de Barcelona
The contribution of genetic ancestry on chronic obstructive pulmonary disease (COPD) predisposition remains unclear. To explore this relationship, we analyzed the associations between 754,159 single nucleotide polymorphisms (SNPs) and risk of COPD (n = 214 cases, 193 healthy controls) in Talca, Chile, considering the genetic ancestry and established risk factors. [...]
2020 - 10.3390/jpm10030093
Journal of personalized medicine, Vol. 10 (august 2020)  
4.
16 p, 2.9 MB Deficient pulmonary IFN-β expression in COPD patients / García-Valero, José (Universitat de Barcelona. Departament de Biologia Cel·lular) ; Olloquequi, Jordi (Universidad Autónoma de Chile. Instituto de Ciencias Biomédicas.) ; Montes, Juan F. (Universitat de Barcelona. Departament de Biologia Cel·lular) ; Rodríguez, Ester. (Hospital Universitari Vall d'Hebron) ; Martín-Satué, Mireia (Institut d'Investigació Biomèdica de Bellvitge) ; Texidó, Laura (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Ferrer Sancho, Jaume 1958- (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
COPD patients are prone to acute infectious exacerbations that impair their quality of life and hamper prognosis. The purpose of the present study was to investigate the in situ IFN-Ǝ response in the lungs of stable COPD and non-COPD patients. [...]
2019 - 10.1371/journal.pone.0217803
PloS one, Vol. 14 Núm. 6 (june 2019) , p. e0217803  

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