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10 p, 2.4 MB Tuning the endocytosis mechanism of Zr-based metal–organic frameworks through linker functionalization / Orellana-Tavra, Claudia (University of Cambridge. Adsorption & Advanced Materials Laboratory) ; Haddad, Salame (University of Cambridge. Adsorption & Advanced Materials Laboratory) ; Marshall, Ross J. (University of Glasgow. WestCHEM School of Chemistry) ; Abánades Lázaro, Isabel (University of Glasgow. WestCHEM School of Chemistry) ; Boix, Gerard (Institut Català de Nanociència i Nanotecnologia) ; Imaz, Inhar (Institut Català de Nanociència i Nanotecnologia) ; Maspoch Comamala, Daniel (Institució Catalana de Recerca i Estudis Avançats) ; Forgan, Ross S. (University of Glasgow. WestCHEM School of Chemistry) ; Fairen-Jimenez, David (University of Cambridge. Adsorption & Advanced Materials Laboratory)
A critical bottleneck for the use of metal–organic frameworks (MOFs) as drug delivery systems has been allowing them to reach their intracellular targets without being degraded in the acidic environment of the lysosomes. [...]
2017 - 10.1021/acsami.7b07342
ACS Applied Materials & Interfaces, Vol. 9, Issue 41 (October 2017) , p. 35516-35525  

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