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Articles, 2 records found
Articles 2 records found  
9 p, 1.0 MB HIF pathway and c-Myc as biomarkers for response to sunitinib in metastatic clear-cell renal cell carcinoma / Maroto Rey, José Pablo (Institut d'Investigació Biomèdica Sant Pau) ; Esteban, E (Department of Oncology, Nuevo HUCA, Oviedo) ; Parra, E Fernández (Department of Oncology, H. U. Nuestra Señora de Valme, Sevilla) ; Mendez-Vidal, MJ (Department of Oncology, H. U. Reina Sofía, Córdoba) ; Domenech, M (Department of Oncology, Hospital de Althaia Xarxa Asistencial Manresa, Barcelona) ; Pérez-Valderrama, B (Department of Oncology, H. U. Virgen del Rocio, Sevilla) ; Calderero, V (Department of Oncology, H. Fundación Miguel Servet, Zaragoza) ; Pérez-Gracia, JL (Department of Oncology, Clinica Universitaria de Pamplona, Pamplona) ; Grande, E (Department of Oncology, H. Ramón y Cajal, Madrid) ; Algaba, F (Institut d'Investigació Biomèdica Sant Pau)
Clear-cell renal cell carcinoma (ccRCC) is a heterogeneous disease with a different clinical behavior and response to targeted therapies. Differences in hypoxia-inducible factor (HIF) expression have been used to classify von Hippel–Lindau gene (VHL)-deficient ccRCC tumors. [...]
2017 - 10.2147/OTT.S137677
OncoTargets and therapy, Vol. 10 (september 2017) , p. 4635-4643  
12 p, 5.3 MB Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma / Puente, Javier (Hospital Clínico Universitario San Carlos) ; Laínez, Nuria (Medical Oncology Department, Complejo Hospitalario de Navarra, Pamplona, Spain) ; Dueñas, Marta (CIBERONC, Spain) ; Méndez-Vidal, María José (Medical Oncology Department, Hospital Universitario Reina Sofía, Córdoba, Spain) ; Esteban, Emilio (Medical Oncology Department, Hospital Universitario Central de Asturias, Oviedo, Spain) ; Castellano, Daniel (Medical Oncology Department, and Instituto Investigación Biomédica, Hospital Universitario 12 de Octubre, Madrid, Spain) ; Martinez-Fernández, Mónica (CIBERONC, Spain) ; Basterretxea, Laura (Medical Oncology Department, Hospital Donostia, Donostia, Spain) ; Juan-Fita, María José (Medical Oncology Department, Instituto Valenciano de Oncología, Valencia, Spain) ; Antón, Luis (Medical Oncology Department, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain) ; León, Luis (Promoción e Planificación da Investigación Sanitaria, Axencia de Coñecemento en Saúde, Santiago de Compostela, Spain) ; Lambea, Julio (Medical Oncology Department, Hospital Clínico de Zaragoza, Zaragoza, Spain) ; Pérez-Valderrama, Begoña (Medical Oncology Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain) ; Vázquez, Sergio (Medical Oncology Department, Hospital Universitario Lucus Augusti, Lugo, Spain) ; Suarez, Cristina (Universitat Autònoma de Barcelona) ; del Muro, Xavier Garcia (Institut Català d'Oncologia, Hospital Duran i Reynals) ; Gallardo, Enrique (Medical Oncology Department, Hospital Universitari Parc Taulí, Sabadell, Spain) ; Maroto, José Pablo (Institut d'Investigacions Biomèdiques Sant Pau) ; Samaniego, M Luz (Statistical Department, Trial Form Support TFS people, Madrid, Spain) ; Suárez-Paniagua, Beatriz (Oncology Medical Department, Trial Form Support, Madrid, Spain) ; Sanz, Julián (Pathology Department, Hospital Clínico Universitario San Carlos, Madrid, Spain) ; Paramio, Jesús M. (CIBERONC, Spain)
Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further investigation. [...]
2017 - 10.18632/oncotarget.16494
Oncotarget, Vol. 8 (march 2017) , p. 30410-30421  

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1 Pérez-Valderrama, Begoña
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