Resultados globales: 4 registros encontrados en 0.02 segundos.
Artículos, Encontrados 4 registros
Artículos Encontrados 4 registros  
1.
9 p, 846.3 KB Striatal GPR88 modulates foraging efficiency / Rainwater, Aundrea (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències)
The striatum is anatomically and behaviorally implicated in behaviors that promote efficient foraging. To investigate this function, we studied instrumental choice behavior in mice lacking GPR88, a striatum-enriched orphan G-protein-coupled receptor that modulates striatal medium spiny neuron excitability. [...]
2017 - 10.1523/JNEUROSCI.2439-16.2017
The Journal of Neuroscience, Vol. 37, Núm. 33 (August 2017) , p. 7939-7947  
2.
8 p, 2.2 MB Loss of mitochondrial Ndufs4 in striatal medium spiny neurons mediates progressive motor impairment in a mouse model of leigh syndrome / Chen, Byron (University of Washington. Howard Hughes Medical Institute) ; Hui, Jessica (Seattle Children's Research Institute (Seattle, Estats Units d'Amèrica)) ; Montgomery, Kelsey S. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gella, Alejandro (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències)
Inability of mitochondria to generate energy leads to severe and often fatal myoencephalopathies. Among these, Leigh syndrome (LS) is one of the most common childhood mitochondrial diseases; it is characterized by hypotonia, failure to thrive, respiratory insufficiency and progressive mental and motor dysfunction, leading to early death. [...]
2017 - 10.3389/fnmol.2017.00265
Frontiers in molecular neuroscience, Vol. 10 (August 2017) , article 265  
3.
9 p, 1.4 MB Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons. / Beutler, Lisa R. (University of Washington. Department of Genome Sciences) ; Eldred, Kiara C. (Howard Hughes Medical Institute (Estats Units d'Amèrica)) ; Quintana Romero, Albert (University of Washington. Department of Biochemistry) ; Keene, C. Dirk (University of Washington. Department of Pathology) ; Rose, Shannon E. (University of Washington. Department of Pathology) ; Postupna, Nadia (University of Washington. Department of Pathology) ; Montine, Thomas J. (University of Washington. Department of Pathology) ; Palmiter, Richard D. (University of Washington. Department of Genome Sciences)
The striatum is composed predominantly of medium spiny neurons (MSNs) that integrate excitatory, glutamatergic inputs from the cortex and thalamus, and modulatory dopaminergic inputs from the ventral midbrain to influence behavior. [...]
2011 - 10.1371/journal.pone.0028168
PLoS one, Vol. 6 Num. 11 (November 2011) , p. e28168  
4.
28 p, 14.2 MB Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state / Padilla, Stephanie L. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Qiu, Jian (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Soden, Marta E. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nestor, Casey C. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Barker, Forrest D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Zweifel, Larry S. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Rønnekleiv, Oline K. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Kelly, Martin J. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica))
In the face of starvation, animals will engage in high-risk behaviors that would normally be considered maladaptive. Starving rodents, for example, will forage in areas that are more susceptible to predators and will also modulate aggressive behavior within a territory of limited or depleted nutrients. [...]
2016 - 10.1038/nn.4274
Nature neuroscience, Vol. 19, Num. 5 (May 2016) , p. 734-741  

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1 Palmiter, R. D.
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