Resultats globals: 6 registres trobats en 0.02 segons.
Articles, 6 registres trobats
Articles 6 registres trobats  
1.
16 p, 1.2 MB Deucravacitinib in Moderate to Severe Psoriasis : Clinical and Quality-of-Life Outcomes in a Phase 2 Trial / Thaçi, Diamant (University of Luebeck) ; Strober, Bruce (Yale University) ; Gordon, Kenneth B. (Medical College of Wisconsin) ; Foley, Peter (The University of Melbourne) ; Gooderham, Melinda (Queen's University and Probity Medical Research) ; Morita, Akimichi (Nagoya City University) ; Papp, Kim A. (Clinical Research and Probity Medical Research) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Menter, M. Alan (Baylor University Medical Center) ; Colombo, Matthew J. (Bristol Myers Squibb) ; Elbez, Yedid (Bristol Myers Squibb) ; Kisa, Renata M. (Bristol Myers Squibb) ; Ye, June (Bristol Myers Squibb) ; Napoli, Andrew A. (Bristol Myers Squibb) ; Wei, Lan (Bristol Myers Squibb) ; Banerjee, Subhashis (Bristol Myers Squibb) ; Merola, Joseph F. (Harvard Medical School) ; Gottlieb, Alice B. (Icahn School of Medicine at Mount Sinai) ; Universitat Autònoma de Barcelona
Deucravacitinib is an oral, selective tyrosine kinase 2 inhibitor that demonstrated therapeutic benefit in a Phase 2 clinical trial of adults with moderate to severe plaque psoriasis. This analysis was designed to evaluate the effect of deucravacitinib on additional clinical and quality-of-life (QoL) outcomes and assess the relationship between these outcomes in adults with psoriasis. [...]
2022 - 10.1007/s13555-021-00649-y
Dermatology and Therapy, Vol. 12 (january 2022) , p. 495-510  
2.
14 p, 980.7 KB Deterioration of Health-Related Quality of Life After Withdrawal of Risankizumab Treatment in Patients with Moderate-to-Severe Plaque Psoriasis : A Machine Learning Predictive Model / Papp, Kim A. (K Papp Clinical Research and Probity Medical Research) ; Soliman, Ahmed M. (AbbVie, Inc) ; Done, Nicolae (Analysis Group, Inc) ; Carley, Christopher (Analysis Group, Inc) ; Lemus Wirtz, Esteban (Analysis Group, Inc) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Risankizumab has demonstrated efficacy in treating moderate-to-severe psoriasis. The phase-3 IMMhance trial (NCT02672852) examined the effect of continuing versus withdrawing from risankizumab treatment on psoriasis severity, including the Psoriasis Area and Severity Index (PASI) and static Physician Global Assessment (sPGA). [...]
2021 - 10.1007/s13555-021-00550-8
Dermatology and Therapy, Vol. 11 (may 2021) , p. 1291-1304  
3.
18 p, 504.6 KB Safety of Ixekizumab Treatment for up to 5 Years in Adult Patients with Moderate-to-Severe Psoriasis : Results from Greater Than 17,000 Patient-Years of Exposure / Armstrong, April (Keck School of Medicine of the University of Southern California. Department of Clinical Research) ; Paul, Carle (Paul Sabatier University. Dermatology Department, Toulouse University Hospital (CHU)) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Boehncke, Wolf Henning (University of Geneva. Department of Pathology and Immunology) ; Freeman, Michael (The Skin Centre, Benowa, QLD Australia) ; Torii, Hideshi (Tokyo Yamate Medical Center. Division of Dermatology) ; Papp, Kim (K Papp Clinical Research and Probity Medical Research) ; Griffiths, Christopher E. M. (NIHR Manchester Biomedical Research Centre. Dermatology Centre, Salford Royal Hospital, University of Manchester) ; Blauvelt, Andrew (Oregon Medical Research Center) ; Reich, Kristian (Skinflammation® Center, Hamburg, Germany) ; Gooderham, Melinda (Centre for Dermatology and Probity Medical Research, Peterborough, ON Canada) ; Terui, Tadashi (Nihon University School of Medicine. Department of Dermatology) ; Renda, Lisa (Eli Lilly and Company) ; Agada, Noah (Eli Lilly and Company) ; Xu, Wen (Eli Lilly and Company) ; Gallo, Gaia (Eli Lilly and Company) ; Lebwohl, Mark G. (Icahn School of Medicine at Mount Sinai. Department of Dermatology) ; Universitat Autònoma de Barcelona
Long-term safety data are critical for evaluating therapies for psoriasis. Ixekizumab has demonstrated efficacy and is well tolerated for the treatment of moderate-to-severe plaque psoriasis. We examined the safety and tolerability of up to 5 years of ixekizumab therapy in patients with psoriasis. [...]
2019 - 10.1007/s13555-019-00340-3
Dermatology and Therapy, Vol. 10 (november 2019) , p. 133-150  
4.
9 p, 310.0 KB Long-term safety and tolerability of apremilast in patients with psoriasis : Pooled safety analysis for ≥156 weeks from 2 phase 3, randomized, controlled trials (ESTEEM 1 and 2) / Crowley, Jeffrey (Bakersfield Dermatology) ; Thaçi, Diamant (Comprehensive Center for Inflammation Medicine, University Hospital Schleswig-Holstein) ; Joly, Pascal (Department of Dermatology, Hôpital Charles Nicolle, Université de Rouen) ; Peris, Ketty (Universitá Cattolica del Sacro Cuore, Roma) ; Papp,Kim A. (Probity Medical Research, Waterloo) ; Gonçalves, Joana (Celgene Corporation) ; Day, Robert M. (Celgene Corporation) ; Chen, Rongdean (Celgene Corporation) ; Shah, Kamal (Celgene Corporation) ; Ferrándiz, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cather, Jennifer C. (Modern Research Associates, Dallas) ; Universitat Autònoma de Barcelona
BACKGROUND: Randomized, controlled trials demonstrated efficacy and safety of apremilast for moderate-to-severe plaque psoriasis and psoriatic arthritis. OBJECTIVE: Assess long-term safety of oral apremilast in psoriasis patients. [...]
2017 - 10.1016/j.jaad.2017.01.052
Journal of the American Academy of Dermatology, Vol. 77 Núm. 2 (2017) , p. 310  
5.
1 p, 320.3 KB Correction to : Efficacy and Safety of Switching to Ixekizumab in Etanercept Non-Responders: A Subanalysis from Two Phase III Randomized Clinical Trials in Moderate-to-Severe Plaque Psoriasis (UNCOVER-2 and -3) / Blauvelt, Andrew (SW Locust St., Suite G, Portland, OR 97223 USA) ; Papp, Kim A. (Waterloo, Canada) ; Griffiths, Christopher E. M. (Manchester, UK) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Weisman, Jamie (Medical Dermatology Specialists, Inc., Atlanta, GA USA) ; Dutronc, Yves (Indianapolis, IN USA) ; Kerr, Lisa Farmer (Indianapolis, IN USA) ; Ilo, Dapo (Indianapolis, IN USA) ; Mallbris, Lotus (Indianapolis, IN USA) ; Augustin, Matthias (Hamburg, Germany) ; Universitat Autònoma de Barcelona
2018 - 10.1007/s40257-018-0353-x
American Journal of Clinical Dermatology, Vol. 19 (march 2018) , p. 457  
6.
8 p, 420.3 KB Efficacy and Safety of Switching to Ixekizumab in Etanercept Non-Responders : a Subanalysis from Two Phase III Randomized Clinical Trials in Moderate-to-Severe Plaque Psoriasis (UNCOVER-2 and -3) / Blauvelt, Andrew (SW Locust St., Suite G, Portland, USA) ; Papp, Kim A. (Waterloo, Canada) ; Griffiths, Christopher E. M. (Manchester, UK) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Weisman, Jamie (Medical Dermatology Specialists, Inc., Atlanta, GA USA) ; Dutronc, Yves (Indianapolis, IN USA) ; Kerr, Lisa Farmer (Indianapolis, IN USA) ; Ilo, Dapo (Indianapolis, IN USA) ; Mallbris, Lotus (Indianapolis, IN USA) ; Augustin, Matthias (Hamburg, Germany) ; Universitat Autònoma de Barcelona
Patients with psoriasis who have an inadequate response to one biologic may benefit from switching to a new biologic, such as ixekizumab, a high affinity monoclonal antibody that selectively targets interleukin (IL)-17A. [...]
2017 - 10.1007/s40257-016-0246-9
American Journal of Clinical Dermatology, Vol. 18 (january 2017) , p. 273-280  

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