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1.
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23 p, 3.0 MB |
Comparison of cerebral metabolic rate of oxygen, blood flow, and bispectral index under general anesthesia
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Tagliabue, Susanna (Institut de Ciència i Tecnologia de Barcelona. Institut de Recerca en Biomedicina (Barcelona)) ;
da Prat, Ivette Chochron (Hospital Universitari Vall d'Hebron) ;
Sanchez-Guerrero, Angela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Serra, Isabel (Barcelona Supercomputing Center) ;
Kacprzak, Michał (Nalecz Institute of Biocybernetics and Biomedical Engineering PAS (Polònia)) ;
Maruccia, Federica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Silva Martinez, Olga (Hospital Universitari Vall d'Hebron) ;
Weigel, Udo M. (Mediterranean Technology Park (Barcelona)) ;
Nadal Clanchet, Miriam de (Universitat Autònoma de Barcelona) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron) ;
Durduran, Turgut (Institució Catalana de Recerca i Estudis Avançats) ;
Lindner, Claus (Institut de Ciència i Tecnologia de Barcelona. Institut de Recerca en Biomedicina)
The optical measurement of cerebral oxygen metabolism was evaluated. Compare optically derived cerebral signals to the electroencephalographic bispectral index (BIS) sensors to monitor propofol-induced anesthesia during surgery. [...]
2023 -  10.1117/1.NPh.10.1.015006
Neurophotonics, Vol. 10 (march 2023)
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2.
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21 p, 1.1 MB |
Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus : a proof-of-concept study
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Maruccia, Federica (ICFO-Insitut de Ciències Fotòniques) ;
Tagliabue, Susanna (ICFO-Insitut de Ciències Fotòniques) ;
Fischer, Jonas B. (HemoPhotonics) ;
Kacprzak, Michał (Nalecz Institute of Biocybernetics and Biomedical Engineering) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosas, Katiuska (Hospital Universitari Vall d'Hebron) ;
Álvarez, Ignacio Delgado (Hospital Universitari Vall d'Hebron) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Durduran, Turgut (Institució Catalana de Recerca i Estudis Avançats) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona)
Benign external hydrocephalus (BEH) is considered a self-limiting pathology with a good prognosis. However, some children present a pathological intracranial pressure (ICP) characterized by quantitative and qualitative alterations (the so-called B-waves) that can lead to neurological sequelae. [...]
2022 - 10.1117/1.NPh.9.4.045005
Neurophotonics, Vol. 9 (november 2022)
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3.
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11 p, 1.2 MB |
Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis
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Román, E. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Poca Pastor, María Antonia (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Amorós-Figueras, Gerard (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Rosell-Ferrer, J. (Universitat Politècnica de Catalunya) ;
Gely, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Nieto Sáchica, Juan Camilo (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Urgell, Eulàlia (Institut d'Investigació Biomèdica Sant Pau) ;
Ferrero-Gregori, A. (Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO)) ;
Alvarado-Tapias, Edilmar (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cuyàs, Berta (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández, Elvira (Universitat Autònoma de Barcelona) ;
Santesmases Masana, Rosalia (Universitat Autònoma de Barcelona) ;
Guarner-Argente, Carlos (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Escorsell, Àngels (Institut d'Investigació Biomèdica Sant Pau) ;
Soriano, G.. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
The phase angle is a versatile measurement to assess body composition, frailty and prognosis in patients with chronic diseases. In cirrhosis, patients often present alterations in body composition that are related to adverse outcomes. [...]
2021 - 10.1038/s41598-021-99199-8
Scientific reports, Vol. 11 Núm. 1 (december 2021) , p. 20415
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4.
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16 p, 898.0 KB |
Diagnosis and treatment of Chiari malformation type 1 in children : the International Consensus Document
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Massimi, Luca (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Peretta, Paola (AOU Citta' della Salute e della Scienza di Torino) ;
Erbetta, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Solari, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Farinotti, Mariangela (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Ciaramitaro, Palma (AOU Citta' della Salute e della Scienza di Torino) ;
Saletti, Veronica (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Caldarelli, Massimo (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Canheu, Alexandre Casagrande (Universidade Estadual de Londrina) ;
Celada, Carlo ("Associazione Italiana Siringomielia e Arnold Chiari", Garino) ;
Chiapparini, Luisa (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Chieffo, Daniela (Fondazione Policlinico Universitario A Gemelli IRCCS and UCSC) ;
Cinalli, Giuseppe (Santobono-Pausilipon Children's Hospital) ;
Di Rocco, Federico (Université de Lyon) ;
Furlanetto, Marika (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giordano, Flavio (Meyer Pediatric Hospital, Florence) ;
Jallo, George (Johns Hopkins All Children's Hospital) ;
James, Syril (Necker Enfants Malades Hospital) ;
Lanteri, Paola (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Lemarchand, Christian (Conseil Scientifique APAISER S&C, Treillières, France) ;
Messing-Jünger, Martina (Asklepios Kinderklinik) ;
Parazzini, Cecilia (Children Hospital V. Buzzi) ;
Paternoster, Giovanna (Necker Enfants Malades Hospital) ;
Piatelli, Gianluca (Gaslini Children's Hospital) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prabahkar, Prab (Great Ormond Street Hospital for Children, Londres) ;
Ricci, Federica (AOU Citta' della Salute e della Scienza di Torino) ;
Righini, Andrea (Children Hospital V. Buzzi) ;
Sala, Francesco (Great Ormond Street Hospital for Children (Londres)) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Stoodley, Marcus (Macquarie University Clinical Associates) ;
Talamonti, Giuseppe (ASST Niguarda) ;
Thompson, Dominic (Great Ormond Street Hospital for Children (Londres)) ;
Triulzi, Fabio (University of Milan) ;
Zucchelli, Mino (IRCCS Istituto delle Scienze Neurologiche di Bologna) ;
Valentini, Laura (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Universitat Autònoma de Barcelona
Chiari malformation type 1 (CM1) is a rare condition where agreed classification and treatment are still missing. The goal of this study is to achieve a consensus on the diagnosis and treatment of CM1 in children. [...]
2021 - 10.1007/s10072-021-05317-9
Neurological Sciences, Vol. 43 (june 2021) , p. 1311-1326
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5.
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20 p, 1.3 MB |
Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1
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Urbizu, Aintzane (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garrett, Melanie E. (Duke University Medical Center) ;
Soldano, Karen (Duke University Medical Center) ;
Drechsel, Oliver (Universitat Pompeu Fabra) ;
Loth, Dorothy (University of Akron) ;
Marcé-Grau, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mestres i Soler, Olga (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ossowski, Stephan (Universitat Pompeu Fabra) ;
Macaya Ruiz, Alfons (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Loth, Francis (University of Akron) ;
Labuda, Rick (Conquer Chiari (Estats Units d'Amèrica)) ;
Ashley-Koch, Allison (Duke University Medical Center) ;
Universitat Autònoma de Barcelona
Chiari Malformation Type 1 (CM-1) is characterized by herniation of the cerebellar tonsils below the foramen magnum and the presence of headaches and other neurologic symptoms. Cranial bone constriction is suspected to be the most common biologic mechanism leading to CM-1. [...]
2021 - 10.1371/journal.pone.0251289
PloS one, Vol. 16 (may 2021)
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6.
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7.
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11 p, 753.1 KB |
Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism : A Microdialysis Study in Patients with Traumatic Brain Injuries
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Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Merino, Maria-Angels (Hospital Universitari Vall d'Hebron) ;
Sánchez-Guerrero, Angela (Hospital Universitari Vall d'Hebron) ;
Arikan Abelló, Fuat (Hospital Universitari Vall d'Hebron) ;
Vidal-Jorge, Marian (Hospital Universitari Vall d'Hebron) ;
Martínez-Valverde, Tamara (Hospital Universitari Vall d'Hebron) ;
Rey Pérez, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Riveiro, Marilyn (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traumatic brain injury (TBI) subjected to brain microdialysis monitoring to analyze the agreement between these two biomarkers and to indicate brain energy metabolism dysfunction. [...]
2014 - 10.1371/journal.pone.0102540
PloS one, Vol. 9 (july 2014)
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8.
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11 p, 2.2 MB |
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
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Escudero, Laura (Vall d'Hebron Institut d'Oncologia) ;
Llort, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ;
Diaz-Navarro, Ander (Centro de Investigación Biomédica en Red de Cáncer) ;
Martinez-Ricarte, Fran (Universitat Autònoma de Barcelona) ;
Rubio-Perez, Carlota (Vall d'Hebron Institut d'Oncologia) ;
Mayor, Regina (Vall d'Hebron Institut d'Oncologia) ;
Caratù, Ginevra (Vall d'Hebron Institut d'Oncologia) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vázquez-Méndez, Élida (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lesende-Rodríguez, Iván (Universidade da Coruña) ;
Hladun, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gros, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona) ;
Puente, Xose S. (Centro de Investigación Biomédica en Red de Cáncer) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Gallego, Soledad (Universitat Autònoma de Barcelona) ;
Seoane Suárez, Joan (Institució Catalana de Recerca i Estudis Avançats)
The molecular characterisation of medulloblastoma, the most common paediatric brain tumour, is crucial for the correct management and treatment of this heterogenous disease. However, insufficient tissue sample, the presence of tumour heterogeneity, or disseminated disease can challenge its diagnosis and monitoring. [...]
2020 - 10.1038/s41467-020-19175-0
Nature communications, Vol. 11 (october 2020)
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9.
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11 p, 1.2 MB |
Reduced hippocampal subfield volumes and memory performance in preterm children with and without germinal matrix-intraventricular hemorrhage
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Fernández de Gamarra-Oca, Lexuri (Universidad de Deusto) ;
Zubiaurre-Elorza, Leire (Universidad de Deusto) ;
Junqué, Carme (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Solana, Elisabeth (Hospital Clínic i Provincial de Barcelona) ;
Soria-Pastor, Sara (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Vázquez, Élida (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, Ignacio (Hospital Universitari Vall d'Hebron) ;
Macaya Ruiz, Alfons (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ojeda, Natalia (Universidad de Deusto) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Preterm newborns with germinal matrix-intraventricular hemorrhage (GM-IVH) are at a higher risk of evidencing neurodevelopmental alterations. Present study aimed to explore the long-term effects that GM-IVH have on hippocampal subfields, and their correlates with memory. [...]
2021 - 10.1038/s41598-021-81802-7
Scientific reports, Vol. 11 (january 2021)
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10.
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14 p, 1.9 MB |
Considerations in the Use of Gravitational Valves in the Management of Hydrocephalus. Some Lessons Learned with the Dual-Switch Valve
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Poca Pastor, María Antonia (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Gándara, Dario F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosas, Katiuska (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alcina, Aloma (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López-Bermeo, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia)
In the past decade, there has been a clear trend towards better outcomes in patients with hydrocephalus, especially those with normal pressure hydrocephalus (NPH). This is partly due to the availability of more sophisticated hardware and a better understanding of implants. [...]
2021 - 10.3390/jcm10020246
Journal of clinical medicine, Vol. 10 (january 2021)
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