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11 p, 1.4 MB Microchromosomes are building blocks of bird, reptile, and mammal chromosomes / Waters, Paul D. (UNSW Sydney. School of Biotechnology and Biomolecular Science) ; Patel, Hardip R. (Australian National University. The John Curtin School of Medical Research) ; Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Álvarez-González, Lucía (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Lister, Nicholas C. (UNSW Sydney. School of Biotechnology and Biomolecular Science) ; Simakov, Oleg (University of Vienna. Department of Neurosciences and Developmental Biology) ; Ezaz, Tariq (University of Canberra. Institute for Applied Ecology) ; Kaur, Parwinder (The University of Western Australia. UWA School of Agriculture and Environment) ; Frere, Celine (University of the Sunshine Coast (Australia)) ; Grutzner, Frank (University of Adelaide. School of Biological Sciences (Australia)) ; Georges, Arthur (University of Canberra. Institute for Applied Ecology) ; Marshall Graves, Jennifer A. (La Trobe University. School of Life Sciences (Australia))
Microchromosomes, once considered unimportant shreds of the chicken genome, are gene-rich elements with a high GC content and few transposable elements. Their origin has been debated for decades. We used cytological and whole-genome sequence comparisons, and chromosome conformation capture, to trace their origin and fate in genomes of reptiles, birds, and mammals. [...]
2021 - 10.1073/pnas.2112494118
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 45 (November 2021) , art. e2112494118  
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