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8 p, 611.0 KB Development of a Novel Heart Failure Risk Tool: The Barcelona Bio-Heart Failure Risk Calculator (BCN Bio-HF Calculator) / Lupón, Josep (Hospital Germans Trias i Pujol) ; Antonio, Marta de (Hospital Germans Trias i Pujol) ; Vila, Joan (Hospital del Mar. Institut Municipal d'Investigació Mèdica) ; Peñafiel, Judith (Hospital del Mar. Institut Municipal d'Investigació Mèdica) ; Galán, Amparo (Hospital Germans Trias i Pujol) ; Zamora Serrallonga, Elisabet (Hospital Germans Trias i Pujol) ; Urrutia de Diego, Agustín (Hospital Germans Trias i Pujol) ; Bayés Genís, Antoni (Hospital Germans Trias i Pujol)
Background: A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF). A novel calculator (BCN Bio-HF calculator) incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch), high-sensitivity cardiac troponin T (hs-cTnT, a marker of myocyte injury), and high-sensitivity soluble ST2 (ST2), (reflective of myocardial fibrosis and remodeling) was developed. [...]
2014 - 10.1371/journal.pone.0085466
PloS one, Vol. 9, Issue 1 (January 2014) , p.e85466  

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