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17 p, 1.2 MB Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer / Kotwinski, Paul (East and North Hertfordshire NHS Trust (Stevenage, Regne Unit)) ; Smith, Gillian (Royal Brompton Hospital (Londres)) ; Cooper, Jackie (University College London) ; Sanders, Julie (Institute for Human Health and Performance (Londres)) ; Ma, Louise (Institute for Human Health and Performance (Londres)) ; Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Kotwinski, David (Institute for Human Health and Performance (Londres)) ; Mythen, Michael (University College Hospital (Londres)) ; Pennell, Dudley J. (Royal Brompton Hospital (Londres)) ; Jones, Alison (UCL Institute of Cardiovascular Science (Londres)) ; Montgomery, Hugh (Institute for Human Health and Performance (Londres))
Background and aims: Anthracyclines are highly effective chemotherapeutic agents which may cause long-term cardiac damage (chronic anthracycline cardiotoxicity) and heart failure. The pathogenesis of anthracycline cardiotoxicity remains incompletely understood and individual susceptibility difficult to predict. [...]
2016 - 10.1371/journal.pone.0165262
PloS one, Vol. 11 Núm. 12 (December 2016)  
Registre complet - Creative Commons

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