Results overview: Found 6 records in 0.02 seconds.
Articles, 6 records found
Articles 6 records found  
1.
12 p, 3.6 MB Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction / Lluciá Valldeperas, Aida (Institut Germans Trias i Pujol) ; Soler Botija, Carolina (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol) ; Perea Gil, Isaac (Institut Germans Trias i Pujol) ; Sanchez, Benjamin (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Bragos, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Vunjak-Novakovic, Gordana (Columbia University. Biomedical Engineering and Medicine) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. [...]
2017 - 10.5966/sctm.2016-0079
Stem cells translational medicine, Vol. 6 (2017) , p. 970-981  
2.
9 p, 3.9 MB Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing / Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; Bragós, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Díaz-Güemes, Idoia (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Crisóstomo, Verónica (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Sánchez Margallo, Francisco M. (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Llucià Vallperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Bogónez Franco, Francisco Carlos (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. [...]
2017 - 10.5966/sctm.2016-0063
Stem cells translational medicine, Vol. 6 (2017) , p. 647-655  
3.
13 p, 3.7 MB A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function / Perea-Gil, Isaac (Institut Germans Trias i Pujol) ; Prat-Vidal, Cristina (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Center of Regenerative Medicine in Barcelona, Barcelona, Spain) ; Llucià-Valldeperas, Aida (Institut Germans Trias i Pujol) ; Soler-Botija, Carolina (Institut Germans Trias i Pujol) ; Iborra Egea, Oriol (Institut Germans Trias i Pujol) ; Díaz-Güemes, Idoia (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Crisóstomo, Verónica (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Sánchez-Margallo, Francisco M. (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment. Here, the authors engineered a cell-enriched myocardial graft, composed of a decellularized myocardial matrix refilled with adipose tissue-derived progenitor cells (EMG-ATDPC). [...]
2016 - 10.1016/j.jacbts.2016.06.005
JACC: Basic to Translational Science, Vol. 1 (august 2016) , p. 360-372  
4.
12 p, 2.1 MB Unravelling the effects of mechanical physiological conditioning on cardiac adipose tissue-derived progenitor cells in vitro and in silico / Llucià Valldeperas, Aida (Institut Germans Trias i Pujol) ; Bragós, Ramon (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Soler Botija, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol) ; Perea Gil, Isaac (Institut Germans Trias i Pujol) ; Bayés Genís, Antoni (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Mechanical conditioning is incompletely characterized for stimulating therapeutic cells within the physiological range. We sought to unravel the mechanism of action underlying mechanical conditioning of adipose tissue-derived progenitor cells (ATDPCs), both in vitro and in silico. [...]
2018 - 10.1038/s41598-017-18799-5
Scientific reports, Vol. 8 (january 2018)  
5.
9 p, 1.3 MB Mechanisms of action of sacubitril/valsartan on cardiac remodeling : a systems biology approach / Iborra-Egea, Oriol (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Perea-Gil, Isaac (Institut Germans Trias i Pujol) ; Prat-Vidal, Cristina (Institut Germans Trias i Pujol) ; Soler-Botija, Carolina (Institut Germans Trias i Pujol) ; Bayes-Genis, Antoni (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Sacubitril/Valsartan, proved superiority over other conventional heart failure management treatments, but its mechanisms of action remains obscure. In this study, we sought to explore the mechanistic details for Sacubitril/Valsartan in heart failure and post-myocardial infarction remodeling, using an in silico, systems biology approach. [...]
2017 - 10.1038/s41540-017-0013-4
NPJ Systems Biology and Applications, Vol. 3 (april 2017)  
6.
10 p, 723.5 KB Extracellular vesicles do not contribute to higher circulating levels of soluble 1 in idiopathic dilated cardiomyopathy / Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; de Gonzalo Calvo, David (Institut d'Investigació Biomèdica Sant Pau) ; Valero, Ana Gámez (Institut Germans Trias i Pujol) ; Gastelurrutia, Paloma (Institut Germans Trias i Pujol. ICREC) ; Revuelta López, Elena (Institut Germans Trias i Pujol. ICREC) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Llucià Valldeperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Iborra Egea, Oriol (Institut Germans Trias i Pujol. ICREC) ; Borràs, Francesc E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Llorente Cortés, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Universitat Autònoma de Barcelona
Idiopathic dilated cardiomyopathy () is a frequent cause of heart transplantation. Potentially valuable blood markers are being sought, and low-density lipoprotein receptor-related protein 1 (1) has been linked to the underlying molecular basis of the disease. [...]
2017 - 10.1111/jcmm.13211
Journal of Cellular and Molecular Medicine, Vol. 21 (may 2017) , p. 3000-3009  

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.