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9 p, 628.7 KB |
Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis
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Fissolo, Nicolás (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pappolla, Agustin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Río, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Villar, Luisa M. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gutierrez, Lucía (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
BACKGROUND AND OBJECTIVES: To identify biomarkers associated with treatment response in patients with multiple sclerosis (MS) treated with the oral therapies teriflunomide, dimethyl fumarate (DMF), and fingolimod. [...]
2023 -  10.1212/NXI.0000000000200050
Neurology® neuroimmunology & neuroinflammation, Vol. 10 Núm. 1 (january 2023)
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11 p, 299.2 KB |
Efavirenz versus boosted atazanavir-containing regimens and immunologic, virologic, and clinical outcomes : A prospective study of HIV-positive individuals
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Cain, Lauren E. (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Caniglia, Ellen C. (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Phillips, Andrew (University College London) ;
Olson, Ashley ;
Muga, Roberto (Institut Germans Trias i Pujol) ;
Pérez Hoyos, Santiago ;
Abgrall, Sophie ;
Costagliola, Dominique ;
Rubio, Rafael ;
Jarrín, Inma ;
Bucher, Heiner ;
Fehr, Jan ;
van Sighem, Ard ;
Reiss, Peter ;
Dabis, François ;
Vandenhende, Marie-Anne ;
Logan, Roger ;
Robins, James ;
Sterne, Jonathan A C ;
Justice, Amy ;
Tate, Janet ;
Touloumi, Giota ;
Paparizos, Vasilis ;
Esteve, Anna ;
Casabona-Barbarà, Jordi ;
Seng, Rémonie ;
Meyer, Laurence ;
Jose, Sophie ;
Sabin, Caroline A ;
Hernán, Miguel A ;
HIV CAUSAL Collaboration ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Objective: To compare regimens consisting of either ritonavir-boosted atazanavir or efavirenz and a nucleoside reverse transcriptase inhibitor (NRTI) backbone with respect to clinical, immunologic, and virologic outcomes. [...]
2016 - 10.1097/MD.0000000000005133
Medicine, Vol. 95 Núm. 41 (2016) , art. e5133
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3.
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21 p, 1.1 MB |
Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus : a proof-of-concept study
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Maruccia, Federica (ICFO-Insitut de Ciències Fotòniques) ;
Tagliabue, Susanna (ICFO-Insitut de Ciències Fotòniques) ;
Fischer, Jonas B. (HemoPhotonics) ;
Kacprzak, Michał (Nalecz Institute of Biocybernetics and Biomedical Engineering) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosas, Katiuska (Hospital Universitari Vall d'Hebron) ;
Álvarez, Ignacio Delgado (Hospital Universitari Vall d'Hebron) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Durduran, Turgut (Institució Catalana de Recerca i Estudis Avançats) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona)
Benign external hydrocephalus (BEH) is considered a self-limiting pathology with a good prognosis. However, some children present a pathological intracranial pressure (ICP) characterized by quantitative and qualitative alterations (the so-called B-waves) that can lead to neurological sequelae. [...]
2022 - 10.1117/1.NPh.9.4.045005
Neurophotonics, Vol. 9 (november 2022)
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4.
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11 p, 1.1 MB |
Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic : Time Series Analysis and Impact of Socioeconomic Factors
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Álvarez-Martín, Claudia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribera, A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ariza-Solé, Albert (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Oristrell, Gerard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soriano-Colomé, Toni (Hospital Universitari Vall d'Hebron) ;
Romaguera, Rafael (Institut d'Investigació Biomèdica de Bellvitge) ;
Pijoan, Jose Ignacio (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Lidón, Rosa M. (Hospital Universitari Vall d'Hebron) ;
Mauri, Josepa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ferreira-Gonzalez, Ignacio (Hospital Universitari Vall d'Hebron)
This study aimed to evaluate the decline in urgent cardiovascular hospital admissions and in-hospital mortality during the COVID pandemic in two successive waves, and to evaluate differences by sex, age, and deprivation index subgroups. [...]
2022 - 10.3389/fcvm.2022.935850
Frontiers in Cardiovascular Medicine, Vol. 9 (april 2022)
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7 p, 427.0 KB |
Unhealthy Alcohol Use, HIV Infection and Risk of Liver Fibrosis in Drug Users with Hepatitis C
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Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tor Aguilera, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez, Elisenda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muñoz, Alvaro (Johns Hopkins University. Bloomberg School of Public Health) ;
Universitat Autònoma de Barcelona
To analyze alcohol use, clinical data and laboratory parameters that may affect FIB-4, an index for measuring liver fibrosis, in HCV-monoinfected and HCV/HIV-coinfected drug users. Patients admitted for substance abuse treatment between 1994 and 2006 were studied. [...]
2012 - 10.1371/journal.pone.0046810
PloS one, Vol. 7 (october 2012)
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12 p, 2.1 MB |
The long-term outcomes of CIS patients in the Barcelona inception cohort : Looking back to recognize aggressive MS
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Tintoré, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arrambide, Georgina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Otero-Romero, Susana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carbonell-Mirabent, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Río, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tur, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nos, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arévalo, María Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Anglada, Elisenda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Menendez, Rebeca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Midaglia, Luciana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Galan, Ingrid (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castilló, Joaquín (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mulero, P. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zabalza, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodríguez-Acevedo, Breogán (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Espejo, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sequeira, Joao (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mitjana, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Barros, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pareto, Deborah (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Auger, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
To explore the long-term outcomes of patients with clinically isolated syndromes from the Barcelona cohort. We selected patients with a follow-up longer than 10 years to (1) estimate the risks of multiple sclerosis (MS) and disability accumulation according to the baseline number of T2 lesions and to compare treated versus untreated patients and early versus delayed treatment, and (2) to study baseline features of patients with aggressive MS (Expanded Disability Status Scale (EDSS) ⩾6. [...]
2019 - 10.1177/1352458519877810
Multiple sclerosis, Vol. 26 (october 2019) , p. 1658-1669
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10 p, 331.3 KB |
Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis
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Zuluaga Rodas, María Isabel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Otero-Romero, Susana (Hospital Universitari Vall d'Hebron) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arrambide, Georgina (Hospital Universitari Vall d'Hebron) ;
Negrotto, L. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Galan, Ingrid (Hospital Universitari Vall d'Hebron) ;
Río, Jordi (Hospital Universitari Vall d'Hebron) ;
Comabella, Manuel (Hospital Universitari Vall d'Hebron) ;
Nos, Carlos. (Hospital Universitari Vall d'Hebron) ;
Arévalo, María Jesús (Hospital Universitari Vall d'Hebron) ;
Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron) ;
Castilló, Joaquín (Hospital Universitari Vall d'Hebron) ;
Rodríguez Acevedo, Breogán (Hospital Universitari Vall d'Hebron) ;
Midaglia, Luciana (Hospital Universitari Vall d'Hebron) ;
Mulero, P. (Hospital Universitari Vall d'Hebron) ;
Mitjana, Raquel (Hospital Universitari Vall d'Hebron) ;
Auger, Cristina (Hospital Universitari Vall d'Hebron) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tintoré, Mar (Division of Neurology. St. Michael's Hospital. University of Toronto) ;
Universitat Autònoma de Barcelona
ObjectiveTo investigate the effect of menarche, pregnancies, and breastfeeding on the risk of developing multiple sclerosis (MS) and disability accrual using a multivariate approach based on a large prospective cohort of patients with clinically isolated syndrome (CIS). [...]
2019 - 10.1212/WNL.0000000000007178
Neurology, Vol. 92 Núm. 13 (26 2019) , p. E1507-E1516
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11 p, 337.0 KB |
Dose variations in tumor volumes and organs at risk during IMRT for head-and-neck cancer
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Beltran, Mercè (Hospital Universitari Vall d'Hebron) ;
Ramos, Mónica (Hospital Universitari Vall d'Hebron) ;
Rovira, Juan José (Hospital Universitari Vall d'Hebron) ;
Perez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sancho, Marc (Hospital Universitari Vall d'Hebron) ;
Puertas, Enrique (Hospital Universitari Vall d'Hebron) ;
Benavente, Sergi (Hospital Universitari Vall d'Hebron) ;
Ginjaume, Mercè (Universitat Politècnica de Catalunya. Institut de Tècniques Energètiques) ;
Giralt López de Sagredo, Jordi (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Many head-and-neck cancer (HNC) patients treated with radiotherapy suffer significant anatomical changes due to tumor shrinkage or weight loss. The purpose of this study was to assess dose changes over target volumes and organs at risk during intensity-modulated radiotherapy for HNC patients. [...]
2012 - 10.1120/jacmp.v13i6.3723
Journal of Applied Clinical Medical Physics, Vol. 13 (november 2012) , p. 101-111
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9 p, 319.8 KB |
Limiting Cumulative HIV Viremia Copy-Years by Early Treatment Reduces Risk of AIDS and Death
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Olson, Ashley D. (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Walker, A. Sarah (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Suthar, Amitabh B. (South African Centre for Epidemiological Modelling and Analysis, University of Stellenbosch, South Africa) ;
Sabin, Caroline A. (Department of Infection and Population Health, University College London (UCL), London, United Kingdom) ;
Bucher, Heiner (University Hospital Basel (Basilea, Suïssa)) ;
Jarrín, Inmaculada (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Moreno, Santiago (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Porter, Kholoud (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Ford, Deborah (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. Viremia copy-years (VCY), a time-updated measure of cumulative HIV exposure, predicts AIDS/death; although its utility in deciding when to start combination antiretroviral therapy (cART) remains unclear. [...]
2016 - 10.1097/QAI.0000000000001029
Journal of acquired immune deficiency syndromes (1999), Vol. 73 (august 2016) , p. 100-108
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