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11 p, 1.9 MB Effect of Oxidative Damage on the Stability and Dimerization of Superoxide Dismutase 1 / Petrov, Drazen (University of Vienna. Department of Structural and Computational Biology) ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Zagrovic, Bojan (University of Vienna. Department of Structural and Computational Biology)
During their life cycle, proteins are subject to different modifications involving reactive oxygen species. Such oxidative damage to proteins may lead to the formation of insoluble aggregates and cytotoxicity and is associated with age-related disorders including neurodegenerative diseases, cancer, and diabetes. [...]
2016 - 10.1016/j.bpj.2016.02.037
Biophysical Journal, Vol. 110, Issue 7 (April 2016) , p. 1499-1509  

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