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1.
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3 p, 207.7 KB |
In reply : Sex-specific outcomes in COVID-19: missing pieces of the puzzle
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Wolff, Georg (Heinrich-Heine-University Düsseldorf) ;
Wernly, Bernhard (Paracelsus Medical University) ;
Flaatten, Hans (University of Bergen) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Bruno, Raphael Romano (Heinrich-Heine-University Düsseldorf) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pinto, Bernardo Bollen (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Kelm, Malte (Heinrich-Heine-University Düsseldorf) ;
Binneboessel, Stephan (Heinrich-Heine-University Düsseldorf) ;
Baldia, Philipp Heinrich (Heinrich-Heine-University Düsseldorf) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sivri, Sigal (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Flamm, Maria (Paracelsus Medical University) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Centro Hospitalar Universitário de Lisboa Central) ;
Boumendil, Ariane (Hôpital Saint-Antoine) ;
De Lange, Dylan W. (University Utrecht) ;
Guidet, Bertrand (Hôpital Saint-Antoine) ;
Leaver, Susannah (St George's University Hospitals NHS Foundation Trust) ;
Jung, Christian (Heinrich-Heine-University Düsseldorf) ;
Universitat Autònoma de Barcelona
2023 -  10.1007/s12630-023-02470-x
Canadian Journal of Anaesthesia, may 2023, p. 1-3
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2.
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10 p, 1.1 MB |
Outcomes of patients aged ≥80 years with respiratory failure initially treated with non-invasive ventilation in European intensive care units before and during COVID-19 pandemic
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Polok, Kamil (Jagiellonian University Medical College) ;
Fronczek, Jakub (Jagiellonian University Medical College) ;
Guidet, Bertrand (Sorbonne Universités) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
De Lange, Dylan W. (University Utrecht) ;
Fjølner, Jesper (Viborg Regional Hospital) ;
Leaver, Susannah (St George's Hospital) ;
Beil, Michael (Hadassah Medical Center) ;
Sviri, Sigal (Hebrew University of Jerusalem) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Wernly, Bernhard (Paracelsus Medical University) ;
Pinto, Bernardo Bollen (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Studzińska, Dorota (Jagiellonian University Medical College) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Marsh, Brian (Mater Misericordiae University Hospital) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Universidade da Beira Interior) ;
Cecconi, Maurizio (Humanitas Research Hospital (Itàlia)) ;
Flaatten, Hans (University of Bergen) ;
Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Universitat Autònoma de Barcelona
Non-invasive ventilation (NIV) has been commonly used to treat acute respiratory failure due to COVID-19. In this study we aimed to compare outcomes of older critically ill patients treated with NIV before and during the COVID-19 pandemic. [...]
2023 - 10.1186/s13613-023-01173-2
Annals of Intensive Care, Vol. 13 (september 2023)
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3.
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9 p, 295.2 KB |
Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age-results from the prospective COVIP study
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Wolff, Georg (Heinrich-Heine-University Düsseldorf) ;
Wernly, Bernhard (Paracelsus Medical University) ;
Flaatten, Hans (University of Bergen) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Bruno, Raphael Romano (Heinrich-Heine-University Düsseldorf) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pinto, Bernardo Bollen (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Kelm, Malte (Heinrich-Heine-University Düsseldorf) ;
Binneboessel, Stephan (Heinrich-Heine-University Düsseldorf) ;
Baldia, Philipp Heinrich (Heinrich-Heine-University Düsseldorf) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sivri, Sigal (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Flamm, Maria (Paracelsus Medical University) ;
Zafeiridis, Tilemachos (General University Hospital of Larissa (Grècia)) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Nova Médical School) ;
Boumendil, Ariane (Sorbonne Universités) ;
De Lange, Dylan W. (University Medical Center) ;
Guidet, Bertrand (Sorbonne Universités) ;
Leaver, Susannah (St George's University Hospitals NHS Foundation Trust) ;
Jung, Christian (Heinrich-Heine-University) ;
Universitat Autònoma de Barcelona
Older critically ill patients with COVID-19 have been the most vulnerable during the ongoing pandemic, with men being more prone to hospitalization and severe disease than women. We aimed to explore sex-specific differences in treatment and outcome after intensive care unit (ICU) admission in this cohort. [...]
2022 - 10.1007/s12630-022-02304-2
Canadian Journal of Anaesthesia, august 2022, p. 1-9
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4.
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9 p, 1.2 MB |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems
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Wernly, Bernhard (General Hospital Oberndorf) ;
Flaatten, Hans (Haukeland University Hospital (Bergen, Noruega)) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Fjølner, Jesper (Viborg Regional Hospital) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pinto, Bernardo Bollen (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Kelm, Malte (Heinrich-Heine-University Duesseldorf) ;
Sigal, Sviri (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Rezar, Richard (Paracelsus Medical University of Salzburg) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Wolff, Georg (Heinrich-Heine-University Duesseldorf) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Universidade da Beira Interior) ;
Wernly, Sarah (General Hospital Oberndorf) ;
Leaver, Susannah (St. George's University Hospital NHS Foundation Trust) ;
Boumendil, Ariane (Hôpital Saint-Antoine (França)) ;
De Lange, Dylan W. (University Utrecht) ;
Guidet, Bertrand (Hôpital Saint-Antoine (França)) ;
Perings, Stefan (Heinrich-Heine-University Duesseldorf) ;
Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Universitat Autònoma de Barcelona
In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in intensive care units in a THS or SHI. [...]
2022 - 10.1038/s41598-022-21580-y
Scientific reports, Vol. 12 (october 2022)
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20 p, 2.6 MB |
COVID-19 machine learning model predicts outcomes in older patients from various European countries, between pandemic waves, and in a cohort of Asian, African, and American patients
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Mamandipoor, Behrooz (Fondazione Bruno Kessler Research Institute) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Wernly, Bernhard (Paracelsus Medical University (Austria)) ;
Wolff, Georg (Heinrich-Heine-University Duesseldorf (Alemanya)) ;
Fjølner, Jesper (Viborg Regional Hospital (Dinamarca)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pinto, Bernardo Bollen (Geneva University Hospitals (Suïssa)) ;
Schefold, Joerg C. (University of Bern) ;
Kelm, Malte (University Hospital. Department of Cardiology, Pulmonology and Angiology) ;
Beil, Michael (Hadassah Medical Center) ;
Sigal, Sviri (Hebrew University of Jerusalem) ;
Leaver, Susannah (St George's University Hospitals NHS Foundation trust) ;
De Lange, Dylan W. (University Utrecht.) ;
Guidet, Bertrand (Hôpital Saint-Antoine (França)) ;
Flaatten, Hans (Haukeland University Hospital (Noruega)) ;
Szczeklik, Wojciech (Jagiellonian University Medical College (Polònia)) ;
Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Osmani, Venet (Fondazione Bruno Kessler Research Institute (Itàlia)) ;
Universitat Autònoma de Barcelona
COVID-19 remains a complex disease in terms of its trajectory and the diversity of outcomes rendering disease management and clinical resource allocation challenging. Varying symptomatology in older patients as well as limitation of clinical scoring systems have created the need for more objective and consistent methods to aid clinical decision making. [...]
2022 - 10.1371/journal.pdig.0000136
PLOS Digital Health, Vol. 1 (november 2022)
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9 p, 930.0 KB |
Diabetes mellitus is associated with 90-day mortality in old critically ill COVID-19 patients : a multicenter prospective observational cohort study
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Mayerhöfer, Timo (Medical University Innsbruck) ;
Klein, Sebastian (Medical University Innsbruck) ;
Wernly, Bernhard (Paracelsus Medical University of Salzburg) ;
Flaatten, Hans (Haukeland University Hospital (Noruega)) ;
Guidet, Bertrand (Assistance Publique-Hôpitaux de Paris) ;
De Lange, Dylan W. (University Utrecht) ;
Fjølner, Jesper (Viborg Regional Hospital) ;
Leaver, Susannah (St George's Hospital) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sviri, Sigal (Hebrew University of Jerusalem) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Pinto, Bernardo Bollen (Geneva University Hospitals (Suïssa)) ;
Schefold, Joerg C. (Bern University Hospital) ;
Moreno, Rui (UCentro Hospitalar Universitário de Lisboa Central) ;
Cecconi, Maurizio (Humanitas University (Itàlia)) ;
Szczeklik, Wojciech (Jagiellonian University Medical College Center for Intensive Care and Perioperative Medicine) ;
Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Joannidis, Michael (Medical University Innsbruck) ;
Universitat Autònoma de Barcelona
Several studies have found an association between diabetes mellitus, disease severity and outcome in COVID-19 patients. Old critically ill patients are particularly at risk. This study aimed to investigate the impact of diabetes mellitus on 90-day mortality in a high-risk cohort of critically ill patients over 70 years of age. [...]
2023 - 10.1007/s15010-023-02001-2
Infection, march 2023, p. 1-9
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7.
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9 p, 614.7 KB |
Steroid use in elderly critically ill COVID-19 patients
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Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Wernly, Bernhard (Paracelsus Medical University) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Dudzinski, David (Massachusetts General Hospital (Boston)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pinto, Bernardo Bollen (Geneva University Hospitals (Suïssa)) ;
Schefold, Joerg C. (University of Bern) ;
Wolff, Georg (Heinrich-Heine-University Duesseldorf) ;
Kelm, Malte (Heinrich-Heine-University Duesseldorf) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sigal, Sviri (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Czuczwar, Miroslaw (Medical University of Lublin) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Ghent University Hospital (Bèlgica)) ;
Zafeiridis, Tilemachos (General University Hospital of Larissa (Grècia)) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian university of Science and Technology) ;
Moreno, Rui (Centro Hospitalar Universitário de Lisboa Central) ;
Cecconi, Maurizio (Humanitas University (Itàlia)) ;
Leaver, Susannah (St Georgés University Hospitals NHS Foundation trust) ;
Boumendil, Ariane (Hôpital Saint-Antoine (França)) ;
De Lange, Dylan W.. (University Utrecht) ;
Guidet, Bertrand (Hôpitaux de Paris) ;
Flaatten, Hans (Haukeland University Hospital (Noruega)) ;
Universitat Autònoma de Barcelona
More than a year after the onset of the SARS-Cov-2 pandemic, treating patients with COVID-19 remains a challenge. By contrast to the rapid development of effective vaccines against SARS-Cov-2, the development of specific and effective therapeutics against COVID-19 remains largely unresolved. [...]
2021 - 10.1183/13993003.00979-2021
European respiratory journal, june 2021
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8.
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18 p, 1.2 MB |
Feature selection for the accurate prediction of septic and cardiogenic shock ICU mortality in the acute phase
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Aushev, Alexander (Universitat Politècnica de Catalunya. Departament de Ciències de la Computació) ;
Ripoll, Vicent Ribas (Eurecat. Centre Tecnològic de Catalunya) ;
Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament de Ciències de la Computació) ;
Aletti, Federico (University of California San Diego) ;
Pinto, Bernardo Bollen (Hôpitaux Universitaires de Genève) ;
Herpain, Antoine (Université Libre de Bruxelles) ;
Post, Emiel Hendrik (Department of Intensive Care, Hôpital Erasme - Université Libre de Bruxelles, Brussels, Belgium) ;
Medina, Eduardo Romay (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Baselli, Giuseppe (Politecnico di Milano) ;
Bendjelid, Karim (Hôpitaux Universitaires de Genève) ;
Universitat Autònoma de Barcelona
Circulatory shock is a life-threatening disease that accounts for around one-third of all admissions to intensive care units (ICU). It requires immediate treatment, which is why the development of tools for planning therapeutic interventions is required to deal with shock in the critical care environment. [...]
2018 - 10.1371/journal.pone.0199089
PloS one, Vol. 13 (november 2018)
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