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The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments)
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Percie du Sert, Nathalie (National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK) ;
Alfieri, Alessio (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ;
Allan, Stuart M (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Carswell, Hilary VO (Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, UK) ;
Deuchar, Graeme A (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Farr, Tracy D (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ;
Flecknell, Paul (Comparative Biology Centre, Newcastle University, UK) ;
Gallagher, Lindsay (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Gibson, Claire L (Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK) ;
Haley, Michael J (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Macleod, Malcolm R (Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK) ;
McColl, Barry W (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ;
McCabe, Christopher (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Morancho, Anna (Vall d'Hebron Institut de Recerca) ;
Moon, Lawrence DF (Wolfson Centre for Age-Related Diseases, King's College London, London, UK) ;
O'Neill, Michael J (Eli Lilly and Co., Windlesham, Surrey, UK) ;
Pérez de Puig, Isabel (Institut d'Investigacions Biomèdiques de Barcelona) ;
Planas, Anna (Institut d'Investigacions Biomèdiques de Barcelona) ;
Ragan, C Ian (NC3Rs Board, London, UK) ;
Rosell, Anna (Vall d'Hebron Institut de Recerca) ;
Roy, Lisa A (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Ryder, Kathryn O (Home Office, London, UK) ;
Simats, Alba (Vall d'Hebron Institut de Recerca) ;
Sena, Emily S (Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK) ;
Sutherland, Brad A (School of Medicine, Faculty of Health, University of Tasmania, Hobart, Australia) ;
Tricklebank, Mark D (Centre for Neuroimaging Sciences, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK) ;
Trueman, Rebecca C (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ;
Whitfield, Lucy (Royal Veterinary College, London, UK) ;
Wong, Raymond (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Macrae, I Mhairi (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Universitat Autònoma de Barcelona
Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and animal welfare. [...]
2017 - 10.1177/0271678X17709185
Journal of Cerebral Blood Flow & Metabolism, Vol. 37 (august 2017) , p. 3488-3517
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