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1.
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16 p, 1.7 MB |
Challenges and Opportunities With Routinely Collected Data on the Utilization of Cancer Medicines. Perspectives From Health Authority Personnel Across 18 European Countries
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Pisana, Alice (Karolinska Institutet (Estocolm, Suècia)) ;
Wettermark, Björn (Vilnius University) ;
Kurdi, Amanj (Sefako Makgatho Health Sciences University) ;
Tubic, Biljana (University of Banja Luka) ;
Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Zara, Corinne (Servei Català de la Salut) ;
Van Ganse, Eric (Croix Rousse University Hospital (Lyon, França)) ;
Petrova, Guenka (PharmacoEpidemiology Lyon) ;
Mardare, Ileana ("Carol Davila" University of Medicine and Pharmacy) ;
Fürst, Jurij (Health Insurance Institute) ;
Roig-Izquierdo, Marta (Servei Català de la Salut) ;
Melien, Oyvind (Oslo University Hospital (Oslo, Noruega)) ;
Bonanno, Patricia Vella (University of Malta) ;
Banzi, Rita (Istituto di Ricerche Farmacologiche Mario Negri IRCCS) ;
Marković-Peković, Vanda (University of Banja Luka) ;
Mitkova, Zornitsa (PharmacoEpidemiology Lyon) ;
Godman, Brian (Ajman University)
Rising expenditure for new cancer medicines is accelerating concerns that their costs will become unsustainable for universal healthcare access. Moreover, early market access of new oncology medicines lacking appropriate clinical evaluation generates uncertainty over their cost-effectiveness and increases expenditure for unknown health gain. [...]
2022 -  10.3389/fphar.2022.873556
Frontiers in Pharmacology, Vol. 13 (june 2022)
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2.
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0 p, 2.1 MB |
Heterogeneity in pharmacological treatment and outcomes in Crohn's disease patients in Catalonia : a population-based observational study
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Brunet, Eduard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vela, Emili (Catalunya. Generalitat) ;
Melcarne, Luigi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Llovet, Laura-Patricia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Puy, Anna (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cleries, Montserrat (Catalunya. Generalitat) ;
Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Garcia-Iglesias, Pilar (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Villòria, Albert (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Kaplan, Gilaad G. (Departments of Medicine and Community Health Sciences, University of Calgary) ;
Calvet Calvo, Xavier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Heterogeneity in the treatment of a disease is a marker of suboptimal quality of care. The aim of this study is to evaluate the heterogeneity in the treatment used and the outcomes for Crohn's disease (CD) in Catalonia. [...]
2022 - 10.1080/07853890.2022.2069851
Annals of Medicine, Vol. 54 (may 2022) , p. 1255-1264
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7 p, 824.9 KB |
Utilisation of drugs for the treatment of psychiatric diseases in the pediatric population : focus on off-label use
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Pesiou, Stella (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Barcelo, Rafel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Fradera, Marc (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Torres, Ferran (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Pontes García, Caridad (Institut d'Investigació Biomèdica de Bellvitge)
Psychotropics are increasingly used in pediatrics, often as off-label medicines. The guarantees of safety and efficacy are not always granted in clinical practice compared to adult authorised indications. [...]
2023 - 10.3389/fphar.2023.1157135
Frontiers in Pharmacology, Vol. 14 (june 2023)
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4.
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15 p, 4.7 MB |
Is Age the Most Important Risk Factor in COVID-19 Patients? The Relevance of Comorbidity Burden : A Retrospective Analysis of 10,551 Hospitalizations
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Valero-Bover, Damià (Institut d'Investigació Biomèdica de Bellvitge) ;
Monterde, David (Institut d'Investigació Biomèdica de Bellvitge) ;
Carot-Sans, Gerard (Institut d'Investigació Biomèdica de Bellvitge) ;
Cainzos-Achirica, Miguel (Johns Hopkins Medical Institutions) ;
Comín-Colet, Josep (Institut d'Investigació Biomèdica de Bellvitge) ;
Vela, Emili (Institut d'Investigació Biomèdica de Bellvitge) ;
Cleries, Montserrat (Institut d'Investigació Biomèdica de Bellvitge) ;
Folguera, Júlia (Institut d'Investigació Biomèdica de Bellvitge) ;
Abilleira i Castells, Sònia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Arrufat, Miquel (Institut Català de la Salut) ;
Lejardi, Yolanda (Institut Català de la Salut) ;
Solans, Òscar (Institut d'Investigació Biomèdica de Bellvitge) ;
Dedeu, Toni (WHO European Centre for Primary Health Care) ;
Coca, Marc (Institut d'Investigació Biomèdica de Bellvitge) ;
Pérez-Sust, Pol (Institut Català de la Salut) ;
Pontes García, Caridad (Institut d'Investigació Biomèdica de Bellvitge) ;
Piera-Jiménez, Jordi (Institut d'Investigació Biomèdica de Bellvitge) ;
Universitat Autònoma de Barcelona
To assess the contribution of age and comorbidity to the risk of critical illness in hospitalized COVID-19 patients using increasingly exhaustive tools for measuring comorbidity burden. We assessed the effect of age and comorbidity burden in a retrospective, multicenter cohort of patients hospitalized due to COVID-19 in Catalonia (North-East Spain) between March 1, 2020, and January 31, 2022. [...]
2023 - 10.2147/CLEP.S408510
Clinical Epidemiology, Vol. 15 (june 2023) , p. 811-825
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5.
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12 p, 1.1 MB |
Dealing With Immunoglobulin Shortages : A Rationalization Plan From Evidence-Based and Data Collection
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Solís-Díez, Gerard (Servei Català de la Salut) ;
Turu-Pedrola, Marta (Servei Català de la Salut) ;
Roig-Izquierdo, Marta (Servei Català de la Salut) ;
Zara, Corinne (Servei Català de la Salut) ;
Vallano, Antoni (Servei Català de la Salut) ;
Pontes García, Caridad (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
The demand and consumption of immunoglobulins (IgGs) are growing, and there are many difficulties in obtaining supplies. The aim of the study was to analyze the evolution of IgG consumption and cost over a decade, describe the measures implemented for clinical management in the context of regional public health system, and evaluate the initial impact of these measures. [...]
2022 - 10.3389/fpubh.2022.893770
Frontiers in Public Health, Vol. 10 (may 2022)
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6.
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16 p, 1.4 MB |
Changes in Treatment Patterns and Costs for Lung Cancer Have Not Resulted in Relevant Improvements in Survival : A Population-Based Observational Study in Catalonia
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Guarga, Laura (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Paco, Noelia (Servei Català de la Salut) ;
Vela, Emili (Institut d'Investigació Biomèdica de Bellvitge) ;
Cleries, Montserrat (Institut d'Investigació Biomèdica de Bellvitge) ;
Corral, Julieta (Institut d'Investigació Biomèdica de Bellvitge) ;
Delgadillo Duarte, Joaquin (Banc de Sang i Teixits) ;
Pontes García, Caridad (Institut d'Investigació Biomèdica de Bellvitge) ;
Borras, Josep M (Universitat de Barcelona)
Real-world data collect clinical and economic information from daily clinical practice and can support decisions in the context of health evaluation and management. The aim of our retrospective cohort study was to describe the different approaches used for treating lung cancer in Catalonia in 2014 and 2018 and to assess the associated cost and impact on patient survival until December 2021. [...]
2022 - 10.3390/cancers14235791
Cancers, Vol. 14 (november 2022)
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7.
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12 p, 1.5 MB |
Impact of the COVID-19 Pandemic on the Incidence of Suicidal Behaviors : A Retrospective Analysis of Integrated Electronic Health Records in a Population of 7.5 Million
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Valero-Bover, Damià (Institut d'Investigació Biomèdica de Bellvitge) ;
Fradera, Marc (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Carot-Sans, Gerard (Institut d'Investigació Biomèdica de Bellvitge) ;
Parra Uribe, Isabel (Universitat Autònoma de Barcelona) ;
Piera-Jiménez, Jordi (Universitat Oberta de Catalunya. Estudis d'Informàtica, Multimèdia i Telecomunicació) ;
Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Palao, Diego (Universitat Autònoma de Barcelona. Facultat de Medicina)
The COVID-19 pandemic has caused remarkable psychological overwhelming and an increase in stressors that may trigger suicidal behaviors. However, its impact on the rate of suicidal behaviors has been poorly reported. [...]
2022 - 10.3390/ijerph192114364
International journal of environmental research and public health, Vol. 19 (november 2022)
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21 p, 621.9 KB |
The Current Situation Regarding Long-Acting Insulin Analogues Including Biosimilars Among African, Asian, European, and South American Countries; Findings and Implications for the Future
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Godman, Brian (Universiti Sains Malaysia) ;
Haque, Mainul (Universiti Pertahanan Nasional Malaysia) ;
Leong, Trudy (South African National Department of Health) ;
Allocati, Eleonora (Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS) ;
Kumar, Santosh (Department of Periodontology and Implantology, Karnavati University) ;
Islam, Salequl (Department of Microbiology, Jahangirnagar University) ;
Charan, Jaykaran (Department of Pharmacology, All India Institute of Medical Sciences) ;
Akter, Farhana (Department of Endocrinology, Chittagong Medical College) ;
Kurdi, Amanj (Department of Pharmacology, Hawler Medical University) ;
Vassalo, Carlos (Facultad de Ciencias Médicas, Universidad Nacional del Litoral) ;
Bakar, Muhammed Abu (Department of Endocrinology and Metabolism, Chattogram Maa-O-Shishu Hospital Medical College) ;
Rahim, Sagir Abdur (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders General Hospital) ;
Sultana, Nusrat (Department of Endocrinology and Metabolism, Bangabandhu Sheik Mujib Medical University Hospital) ;
Deeba, Farzana (Department of Obstetrics and Gynaecology, Bangabandhu Sheik Mujib Medical University) ;
Khan, M. A. Halim (Shaheed Suhrawardy Medical College Hospital) ;
Alam, A. B. M. Muksudul (Shaheed Suhrawardy Medical College Hospital) ;
Jahan, Iffat (Department of Physiology, Eastern Medical College (Bangladesh)) ;
Kamal, Zubair Mahmood (National Institute of Mental Health (Bangladesh)) ;
Hasin, Humaira (Epsom and St Helier University Hospitals NHS Trust) ;
Munzur-E-Murshid (Women's Integrated Sexual Health (WISH) 2 Access Choice Together Innovate Ownership Now (ACTION) Project, Handicap International (Bangladesh)) ;
Nahar, Shamsun (Department of Microbiology, Jahangirnagar University) ;
Haque, Monami (Human Resource Department Rupayan Center) ;
Dutta, Siddhartha (Department of Pharmacology, All India Institute of Medical Sciences) ;
Abhayanand, Jha Pallavi (Department of Pharmacology, All India Institute of Medical Sciences) ;
Kaur, Rimple Jeet (Department of Pharmacology, All India Institute of Medical Sciences) ;
Rwegerera, Godfrey Mutashambara (University of Botswana) ;
do Nascimento, Renata Cristina Rezende Macedo (Department of Pharmacy, Federal University of Ouro Preto) ;
Dias Godói, Isabella Piassi (Universidade Federal do Sul e Sudeste do Pará) ;
Irfan, Mohammed (Faculdade de Odontologia, Universidade Federal de Pelotas) ;
Amu, Adefolarin A. (Pharmacy Department, Eswatini Medical Christian University) ;
Matowa, Patrick (Pharmacy Department, Eswatini Medical Christian University) ;
Acolatse, Joseph (Cape Coast Teaching Hospital) ;
Incoom, Robert (Cape Coast Teaching Hospital) ;
Sefah, Israel Abebrese (Department of Pharmacy Practise University of Health and Allied Sciences) ;
Acharya, Jitendra (Department of Dentistry, SP Medical College) ;
Opanga, Sylvia (Department of Pharmaceutics and Pharmacy Practise, University of Nairobi) ;
Njeri, Lisper Wangeci (Department of Pharmacy, Kenyatta National Hospital) ;
Kimonge, David (Department of Pharmaceutics and Pharmacy Practise, University of Nairobi) ;
Kwon, Hye-Young (Mokwon University) ;
Bae, SeungJin (Ewha Woman's University) ;
Khuan, Karen Koh Pek (Friends'Pharmacy Pekan Sg Besi 42G) ;
Abubakar, Abdullahi Rabiu (Department of Pharmacology and Therapeutics, Bayero University) ;
Sani, Ibrahim Haruna (Yusuf Maitama Sule University) ;
Khan, Tanveer Ahmed (National Institute of Health) ;
Hussain, Shahzad (National Institute of Health) ;
Saleem, Zikria (Department of Pharmacy Practise, The University of Lahore) ;
Malande, Oliver Ombeva (East Africa Centre for Vaccines and Immunisation) ;
Piloya-Were, Thereza (Makerere University) ;
Gambogi, Rosana (National Resources Fund) ;
Hernandez Ortiz, Carla (National Resources Fund) ;
Alutuli, Luke (University Teaching Hospital Group, Department of Pharmacy) ;
Kalungia, Aubrey Chichonyi (Department of Pharmacy, University of Zambia) ;
Hoxha, Iris (Department of Pharmacy, University of Medicine) ;
Marković-Peković, Vanda (Department of Social Pharmacy, University of Banja Luka) ;
Tubic, Biljana (Department of Medicinal Chemistry, University of Banja Luka) ;
Petrova, Guenka (Medical University of Sofia (Sofia, Bulgària)) ;
Tachkov, Konstantin (Medical University of Sofia (Sofia, Bulgària)) ;
Laius, Ott (State Agency of Medicines) ;
Harsanyi, András (Department of Health Policy and Health Economics, Eotvos Lorand University) ;
Inotai, András (Center of Health Technology Assessment, Semmelweis University) ;
Jakupi, Arianit (UBT Higher Education Institute) ;
Henkuzens, Svens ;
Garuoliene, Kristina (Vilnius University (Vilnius, Lituània)) ;
Gulbinovič, Jolanta (Vilnius University (Vilnius, Lituània)) ;
Wladysiuk, Magdalena (HTA Consulting) ;
Rutkowski, Jakub (HTA Consulting) ;
Mardare, Ileana (Public Health and Management Department, "Carol Davila" University of Medicine and Pharmacy Bucharest) ;
Fürst, Jurij (Health Insurance Institute) ;
McTaggart, Stuart (Public Health Scotland) ;
MacBride-Stewart, Sean (Pharmacy Services, Greater Glasgow and Clyde) ;
Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Zara, Corinne (Servei Català de la Salut) ;
Tagoe, Eunice Twumwaa (Department of Management Science, University of Strathclyde) ;
Banzi, Rita (Istituto di Ricerche Farmacologiche "Mario Negri" IRCCS) ;
Wale, Janney (Independent Consumer Advocate) ;
Jakovljevic, Mihajlo (Hosei University Tokyo)
Background: Diabetes mellitus rates continue to rise, which coupled with increasing costs of associated complications has appreciably increased global expenditure in recent years. The risk of complications are enhanced by poor glycaemic control including hypoglycaemia. [...]
2021 - 10.3389/fpubh.2021.671961
Frontiers in Public Health, Vol. 9 (june 2021)
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10.
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15 p, 807.5 KB |
Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe : methodological uncertainties
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Pontes García, Caridad (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fontanet Sacristán, Juan Manuel (Institut d'Investigació Biomèdica Sant Pau) ;
Vives, Roser (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sancho, Aranzazu (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Gómez-Valent, Mònica (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ríos, José (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Martinalbo, Jorge (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Posch, Martin (Medical University of Vienna) ;
Koch, Armin (Hannover Medical School) ;
Roes, Kit (University of Utrecht, Utrecht, The Netherlands) ;
Rengerink, Katrien Oude (University of Utrecht, Heidelberglaan, CX Utrecht, The Netherlands) ;
Torrent-Farnell, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Torres, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
To assess uncertainty in regulatory decision-making for orphan medicinal products (OMP), a summary of the current basis for approval is required; a systematic grouping of medical conditions may be useful in summarizing information and issuing recommendations for practice. [...]
2018 - 10.1186/s13023-018-0926-z
Orphanet Journal of Rare Diseases, Vol. 13 (november 2018)
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