Resultados globales: 44 registros encontrados en 0.01 segundos.
Artículos, Encontrados 38 registros
Documentos de investigación, Encontrados 6 registros
Artículos Encontrados 38 registros  1 - 10siguientefinal  ir al registro:
1.
14 p, 1.5 MB Effect of Atogepant for Preventive Migraine Treatment on Patient-Reported Outcomes in the Randomized, Double-blind, Phase 3 ADVANCE Trial / Lipton, Richard B. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Blumenfeld, Andrew M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Li, Ye (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Severt, Lawrence (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Stokes, Jonathan T. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Creutz, Lela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gandhi, Pranav (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dodick, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
The oral calcitonin gene-related peptide receptor antagonist atogepant is indicated for the preventive treatment of episodic migraine. We evaluated changes in patient-reported outcomes with atogepant in adults with migraine. [...]
2023 - 10.1212/WNL.0000000000201568
Neurology, Vol. 100 (february 2023) , p. e764-e777  
2.
13 p, 1.9 MB A study of differential microRNA expression profile in migraine : the microMIG exploratory study / Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gómez-Galván, J. B. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Asskour, L. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron) ; Alpuente, Alicia (Hospital Universitari Vall d'Hebron) ; Caronna, Edoardo (Hospital Universitari Vall d'Hebron) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Several studies have described potential microRNA (miRNA) biomarkers associated with migraine, but studies are scarcely reproducible primarily due to the heterogeneous variability of participants. Increasing evidence shows that disease-related intrinsic factors together with lifestyle (environmental factors), influence epigenetic mechanisms and in turn, diseases. [...]
2023 - 10.1186/s10194-023-01542-z
Journal of headache and pain, Vol. 24 (february 2023)  
3.
12 p, 949.5 KB Document of revision and updating of medication overuse headache (MOH) Documento de revisión y actualización de la cefalea por uso excesivo de medicación (CUEM) / González-Oria, Carmen (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Belvís, Roberto (Institut d'Investigació Biomèdica Sant Pau) ; Cuadrado, María Luz (Universidad Complutense de Madrid. Departamento de Medicina) ; Díaz-Insa, Samuel (Hospital Universitari i Politècnic La Fe (València)) ; Guerrero-Peral, Ángel Luis (Hospital Clínico Universitario de Valladolid) ; Huerta, Mariano (Hospital de Viladecans) ; Irimia, Pablo (Clínica Universidad de Navarra) ; Láinez, José Miguel (Hospital Clínic Universitari (València)) ; Latorre, Germán (Hospital Universitario de Fuenlabrada ( Madrid)) ; Leira, Rogelio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Oterino, Agustín (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ; Pascual Gómez, Julio (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ; Porta-Etessam, Jesús (Universidad Complutense de Madrid) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron) ; Sánchez del Río, Margarita (Clínica Universidad de Navarra) ; Santos-Lasaosa, Sonia (Instituto de Investigación Sanitaria de Aragón) ; Universitat Autònoma de Barcelona
Introduction: Medication overuse headache is a secondary headache in which the regular or frequent use of analgesics can increase the frequency of the episodes, causing the transition from episodic to chronic headache. [...]
2021 - 10.1016/j.nrl.2020.04.029
Neurología, Vol. 36 Núm. 3 (abril 2021) , p. 229-240  
4.
5 p, 410.8 KB Interest in and exposure to headache disorders among neurology residents in Denmark : A nationwide cross-sectional survey / Kristensen, Malene Glavind Holmsted (University of Copenhagen) ; Do, Thien Phu (Rigshospitalet Glostrup) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Amin, Faisal Mohammad (University of Copenhagen) ; Universitat Autònoma de Barcelona
Headache disorders constitute a leading cause of disability worldwide, but there is a consistent absence of awareness and educational activities for healthcare providers across regions. Thus, we found it timely to identify potential structural challenges and factors that may affect acquisition of knowledge of headache disorders and their management during their 4-year residency. [...]
2022 - 10.1111/ane.13681
Acta Neurologica Scandinavica, Vol. 146 (august 2022) , p. 568-572  
5.
10 p, 1.4 MB Shift in diagnostic classification of migraine after initiation of preventive treatment with eptinezumab : post hoc analysis of the PROMISE studies / Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dodick, David W. (Atria Institute (Estats Units d'Amèrica)) ; Ettrup, Anders (H. Lundbeck (Copenague)) ; Hirman, Joe (Pacific Northwest Statistical Consulting (Estats Units d'Amèrica)) ; Cady, Roger (Missouri State University) ; Universitat Autònoma de Barcelona
Monthly headache frequency directly correlates with personal/societal burden and impacts severity and preventive treatment decisions. This post hoc analysis identified shifts from higher to lower frequency headache categories over 6 months in patients with migraine participating in the PROMISE clinical trials receiving two eptinezumab doses. [...]
2022 - 10.1186/s12883-022-02914-9
BMC Neurology, Vol. 22 (october 2022)  
6.
12 p, 986.0 KB Perceived barriers to career progression in the headache field : A global web-based cross-sectional survey / de Boer, Irene (Leiden University Medical Center) ; Ambrosini, Anna (IRCCS Neuromed (Itàlia)) ; Halker Singh, Rashmi B (Mayo Clinic (Estats Units d'Amèrica)) ; Baykan, Betül (Istanbul University) ; Buse, Dawn C (DepAlbert Einstein College of Medicine) ; Tassorelli, Cristina (University of Pavia) ; Jensen, Rigmor H (University of Copenhagen) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Terwindt, Gisela M (Leiden University Medical Center) ; Universitat Autònoma de Barcelona
It is well recognized that underrepresented and minoritized groups do not have the same career opportunities. However, there are limited data on the range and specifics of potential barriers that withhold people in headache medicine and science from reaching their full potential. [...]
2022 - 10.1177/03331024221123081
Cephalalgia, Vol. 42 (september 2022) , p. 1498-1509  
7.
10 p, 705.8 KB Migraine-attributed burden, impact and disability, and migraine-impacted quality of life : Expert consensus on definitions from a Delphi process / Steiner, Timothy J (Imperial College London) ; Terwindt, Gisela M (Leiden University Medical Center) ; Katsarava, Zaza (EVEX Medical Corporation (Georgia)) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gantenbein, Andreas R (University Hospital Zurich (Suïssa)) ; Roche, Sarah L (Eli Lilly and Company) ; Dell'Agnello, Grazia (Eli Lilly Italia SpA) ; Tassorelli, Cristina (IRCCS Mondino Foundation) ; Universitat Autònoma de Barcelona
Migraine-attributed burden, impact, disability and migraine-impacted quality of life are important concepts in clinical management, clinical and epidemiological research, and health policy, requiring clear and agreed definitions. [...]
2022 - 10.1177/03331024221110102
Cephalalgia, Vol. 42 (july 2022) , p. 1387-1396  
8.
12 p, 503.9 KB Excellent Response to OnabotulinumtoxinA : Different Definitions, Different Predictors / Ornello, Raffaele (University of L'Aquila) ; Baraldi, Carlo (AOU Policlinico di Modena) ; Ahmed, Fayyaz (Hull University Teaching Hospitals) ; Negro, Andrea (Sapienza University) ; Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ; Santoro, Antonio (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ; Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Russo, Antonio (University of Campania "Luigi Vanvitelli") ; Silvestro, Marcello (University of Campania "Luigi Vanvitelli") ; Cevoli, Sabina (IRCCS Istituto delle Scienze Neurologiche di Bologna) ; Brunelli, Nicoletta (Campus Bio-Medico University Hospital (Itàlia)) ; Vernieri, Fabrizio (Campus Bio-Medico University Hospital (Itàlia)) ; Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute) ; Pani, Luca (VeraSci (Estats Units d'Amèrica)) ; Andreou, Anna P (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ; Frattale, Ilaria (Tor Vergata University) ; Kamm, Katharina (Ludwig Maximilians University München) ; Ruscheweyh, Ruth (Ludwig Maximilians University München) ; Russo, Marco (Azienda USL-IRCCS di Reggio Emilia) ; Torelli, Paola (University of Parma) ; Filatova, Elena (Sechenov First Moscow State Medical University) ; Latysheva, Nina (Sechenov First Moscow State Medical University) ; Gryglas-Dworak, Anna (Headache Center Wroclaw) ; Straburzyński, Marcin (University of Warmia and Mazury) ; Butera, Calogera (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ; Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ; Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martelletti, Paolo (Sapienza University) ; Guerzoni, Simona (University of Modena and Reggio Emilia) ; Sacco, Simona (University of L'Aquila) ; Universitat Autònoma de Barcelona
The identification of patients who can benefit the most from the available preventive treatments is important in chronic migraine. We explored the rate of excellent responders to onabotulinumtoxinA in a multicenter European study and explored the predictors of such response, according to different definitions. [...]
2022 - 10.3390/ijerph191710975
International journal of environmental research and public health, Vol. 19 (september 2022)  
9.
10 p, 1.2 MB In search of a gold standard patient-reported outcome measure to use in the evaluation and treatment-decision making in migraine prevention. A real-world evidence study / Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Caronna, Edoardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Patient-Reported Outcomes (PROs) have been developed to numerically quantify disability, impact and quality of life. They have been widely used in migraine clinical trials. However, we still do not know which PRO more accurately reflects preventive treatment response from a patient's perspective or which one may help us with treatment decisions in clinical practice. [...]
2021 - 10.1186/s10194-021-01366-9
Journal of headache and pain, Vol. 22 (december 2021)  
10.
8 p, 761.9 KB MAB-MIG : registry of the spanish neurological society of erenumab for migraine prevention / Belvís, Roberto (Institut d'Investigació Biomèdica Sant Pau) ; Irimia, Pablo (Clínica Universidad de Navarra) ; Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Oria, Carmen (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Cano, Antonio (Hospital de Mataró. Consorci Sanitari del Maresme) ; Viguera, Javier (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ; Sánchez, Belén (Hospital Quirónsalud Zaragoza) ; Molina, Francisco (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Beltrán, Isabel (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Oterino, Agustín (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Cuadrado-Godia, Elisa (Hospital del Mar (Barcelona, Catalunya)) ; Gómez-Camello, Angel (Hospital Universitario San Cecilio (Granada)) ; Alberte-Woodward, Miguel (Hospital Universitario Lucus Augusti (Lugo)) ; Jurado, Carmen (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ; Oms, Teresa (Hospital Dos de Maig) ; Ezpeleta, David (Hospital Quironsalud Madrid) ; de Terán, Javier Díaz (Hospital Universitario La Paz (Madrid)) ; Morollón Sánchez-Mateos, Noemí (Hospital Universitari Dexeus (Barcelona, Catalunya)) ; Latorre, Germán (Hospital Universitario de Fuenlabrada ( Madrid)) ; Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lamas, Raquel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Toledano, Carlos (Clínica Universidad de Navarra) ; Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ; Santos, Sonia (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ; Del Rio, Margarita Sanchez (Clínica Universidad de Navarra) ; Universitat Autònoma de Barcelona
Erenumab was approved in Europe for migraine prevention in patients with ≥ 4 monthly migraine days (MMDs). In Spain, Novartis started a personalized managed access program, which allowed free access to erenumab before official reimbursement. [...]
2021 - 10.1186/s10194-021-01267-x
Journal of headache and pain, Vol. 22 (july 2021)  

Artículos : Encontrados 38 registros   1 - 10siguientefinal  ir al registro:
Documentos de investigación Encontrados 6 registros  
1.
Impacte dels mecanismes epigenètics en la migranya. Identificació i validació de patrons d'expressió diferencials de microARNs en pacients amb migranya / Gallardo López, Víctor José ; Pozo Rosich, Patricia, dir. ; Álvarez-Sabin, José, dir.
Diversos estudis pilot han estudiat el rol dels microARNs (miARNs) en la migranya. No obstant això, els estudis són poc comparables i reproduïbles degut a l'alt grau d'heterogeneïtat que existeix entre els grups. [...]
Varios estudios piloto han estudiado el rol de los microARNs (miARNs) en la migraña. Sin embargo, los estudios son poco comparables y reproducibles debido al alto grado de heterogeneidad que existe entre los grupos. [...]
Several studies have described the potential role of microRNA (miRNAs) in migraine but studies are scarcely reproducible primarily due to the heterogeneous variability of participants. Hence, the main objective of this project is to identify and validate differentially expressed miRNAs (DE miRNAs) in peripheral blood mononuclear cells (PBMCs) of patients with migraine compared to healthy controls (HC) in a well-controlled homogeneous cohort of participants using a three-step methodology: (a) exploratory study, (b) main study and (c) validation study. [...]

2023  
2.
6.6 MB Migraine molecular phenotyping through the study of the calcitonin gene-related peptide : towards precision medicine / Alpuente, Alicia ; Álvarez Sabín, José, dir. ; Pozo Rosich, Patricia, dir.
S'estableix que el pèptid relacionat amb el gen de la calcitonina (CGRP) juga un paper essencial en la fisiopatologia de la migranya i que el bloqueig del CGRP es una revolució en el tractament preventiu de la migranya amb resultats clínics excel·lents. [...]
Se establece que el péptido relacionado con el gen de la calcitonina (CGRP) juega un papel esencial en la fisiopatología de la migraña y que el bloqueo de CGRP ha supuesto una revolución en el tratamiento preventivo de la migraña con resultados clínicos exitosos. [...]
It is established that the calcitonin gene-related peptide (CGRP) plays an essential role in the pathophysiology of migraine and that its blockade represents a breakthrough in the preventive treatment of migraine with successful clinical results. [...]

2023  
3.
191 p, 5.7 MB Headache attributed to COVID-19 : an opportunity to advance in understanding the pathophysiology of headache disorders / Caronna, Edoardo ; Pozo-Rosich, Patricia, dir. ; Álvarez Sabín, José, dir.
A finals de 2019, va sorgir a la Xina un nou coronavirus, el SARS-CoV-2. La malaltia respiratòria greu, de la qual va ser responsable es va denominar COVID-19. La ràpida difusió del SARS-CoV-2 per tot el món va convertir el COVID-19 en una pandèmia. [...]
A finales de 2019, surgió en China un nuevo coronavirus, el síndrome respiratorio agudo severo coronavirus-2 (SARS-CoV-2). La enfermedad respiratoria, de la que fue responsable el SARS-CoV-2, se denominó enfermedad por coronavirus 2019 (COVID-19). [...]
At the end of 2019, a new coronavirus, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), emerged in China. The severe respiratory infectious disease, for which SARS-CoV-2 was responsible, was named coronavirus disease 2019 (COVID-19). [...]

2022  
4.
148 p, 2.6 MB Impacte de la migranya i factors relacionats / Torres-Ferrús, Marta ; Pozo-Rosich, Patricia, dir. ; Álvarez Sabín, José, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
L'objectiu d'aquesta tesis doctoral és millorar el coneixement de la discapacitat associada a la migranya i els factors que la condicionen per tal de mesurar l'impacte i poder desenvolupar eines que, a nivell clínic i poblacional, ens permetin quantificar millor la discapacitat. [...]
L'objectiu d'aquesta tesis doctoral és millorar el coneixement de la discapacitat associada a la migranya i els factors que la condicionen per tal de mesurar l'impacte i poder desenvolupar eines que, a nivell clínic i poblacional, ens permetin quantificar millor la discapacitat. [...]
The aim of this thesis is to improve the knowledge of the impact of migraine and its associated disability describing and evaluating the factors that influence it, in order to develop tools which will allow us to better measure it in the clinic and society. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  
5.
206 p, 9.3 MB Genètica i epigènetica dels trastorns neurològics paroxístics / Vila Pueyo, Marta ; Macaya Ruiz, Alfons, dir. ; Pozo-Rosich, Patricia, dir. ; Giraldo, Jesús, dir. ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
[Barcelona] : Universitat Autònoma de Barcelona, 2015  
6.
196 p, 6.3 MB Endofenotips, risc genètic i factors que predisposen a la cronificació de la migranya / Fernández Morales, Jessica ; Pozo-Rosich, Patricia, dir. ; Montaner, Joan, dir. ; Álvarez Sabín, José, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Aquesta tesi es centra en l'estudi de la susceptibilitat a desenvolupar migranya crònica (MC). La migranya és un trastorn neurològic caracteritzat per episodis recurrents de mal de cap amb una elevada prevalença, estimada a Espanya en un 12% i que pot arribar a un 18% entre les dones. [...]
This thesis focuses on the study of the susceptibility to develop chronic migraine (CM). Migraine is a neurological disorder characterized by recurrent episodes of headache with a high prevalence estimated at 12% in Spain and that can reach 18% among women. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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