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11 p, 844.8 KB |
Relationship between paramagnetic rim lesions and slowly expanding lesions in multiple sclerosis
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Calvi, Alberto (University College London) ;
Clarke, Margareta A. (Hospital Universitari Vall d'Hebron) ;
Prados Carrasco, Ferran (University College London) ;
Chard, Declan (University College London) ;
Ciccarelli, Olga (University College London) ;
Alberich, Manel (Hospital Universitari Vall d'Hebron) ;
Pareto, Deborah (Hospital Universitari Vall d'Hebron) ;
Rodríguez Barranco, Marta (Hospital Universitari Vall d'Hebron) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ;
Tur, Carmen (Hospital Universitari Vall d'Hebron) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Barkhof, Frederik (University College London) ;
Universitat Autònoma de Barcelona
Magnetic resonance imaging (MRI) markers for chronic active lesions in MS include slowly expanding lesions (SELs) and paramagnetic rim lesions (PRLs). To identify the relationship between SELs and PRLs in MS, and their association with disability. [...]
2022 -  10.1177/13524585221141964
Multiple sclerosis, Vol. 29 (december 2022) , p. 352-362
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2.
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11 p, 1.7 MB |
Regional grey matter microstructural changes and volume loss according to disease duration in multiple sclerosis patients
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Solana, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martinez-Heras, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Vilaplana, E. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Lopez-Soley, E. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Radua, J. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Montejo, C. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Blanco, Yolanda (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pulido-Valdeolivas, I. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sepúlveda, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Andorra, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Berenguer, Juan (Hospital Clínic i Provincial de Barcelona) ;
Villoslada, P. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martinez-Lapiscina, E.H. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Prados, F. (NMR Research Unit. Queen Square MS Centre. Department of Neuroinflammation. UCL Institute of Neurology. University College London) ;
Saiz, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Llufriu, S. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
The spatio-temporal characteristics of grey matter (GM) impairment in multiple sclerosis (MS) are poorly understood. We used a new surface-based diffusion MRI processing tool to investigate regional modifications of microstructure, and we quantified volume loss in GM in a cohort of patients with MS classified into three groups according to disease duration. [...]
2021 - 10.1038/s41598-021-96132-x
Scientific reports, Vol. 11 Núm. 1 (december 2021) , p. 16805
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3.
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14 p, 1.0 MB |
MAGNIMS recommendations for harmonization of MRI data in MS multicenter studies
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De Stefano, Nicola (Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy) ;
Battaglini, Marco (University of Siena) ;
Pareto, Deborah (Hospital Universitari Vall d'Hebron) ;
Cortese, Rosa (University of Siena) ;
Zhang, Jian (University of Siena) ;
Oesingmann, Niels (UK Biobank Stockport) ;
Prados Carrasco, Ferran (Universitat Oberta de Catalunya) ;
Rocca, Maria A. (Vita-Salute San Raffaele University) ;
Valsasina, Paola (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Vrenken, Hugo (MS Center Amsterdam) ;
Gandini Wheeler-Kingshott, Claudia A. M. (University of Pavia) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Barkhof, Frederik (MS Center Amsterdam) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
There is an increasing need of sharing harmonized data from large, cooperative studies as this is essential to develop new diagnostic and prognostic biomarkers. In the field of multiple sclerosis (MS), the issue has become of paramount importance due to the need to translate into the clinical setting some of the most recent MRI achievements. [...]
2022 - 10.1016/j.nicl.2022.102972
NeuroImage, Vol. 34 (february 2022)
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13 p, 1.2 MB |
Progression of regional grey matter atrophy in multiple sclerosis
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Eshaghi, Arman (University College London. Department of Computer Science) ;
Marinescu, Razvan V (University College London. Department of Computer Science) ;
Young, Alexandra L. (University College London. Department of Computer Science) ;
Firth, Nicholas C. (University College London. Department of Computer Science) ;
Prados Carrasco, Ferran (University College London. Department of Medical Physics and Bioengineering) ;
Jorge Cardoso, M. (University College London. Department of Medical Physics and Bioengineering) ;
Tur, Carmen (University College London. Faculty of Brain Sciences) ;
De Angelis, Floriana (University College London. Faculty of Brain Sciences) ;
Cawley, Niamh (University College London. Faculty of Brain Sciences) ;
Brownlee, Wallace J. (University College London. Faculty of Brain Sciences) ;
De Stefano, Nicola (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Laura Stromillo, M. (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Battaglini, Marco (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ;
Ruggieri, Serena (University of Rome Sapienza. Department of Neurology and Psychiatry) ;
Gasperini, Claudio (San Camillo Forlanini Hospital) ;
Filippi, Massimo (Vita-Salute San Raffaele University (Milà, Itàlia)) ;
Rocca, Maria A. (Vita-Salute San Raffaele University (Milà, Itàlia)) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Geurts, Jeroen J. G. (Amsterdam UMC. University Medical Center) ;
Vrenken, Hugo (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Wottschel, Viktor (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Leurs, Cyra E. (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Uitdehaag, Bernard (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Pirpamer, Lukas (Medical University of Graz (Graz, Àustria)) ;
Enzinger, Christian (Medical University of Graz (Graz, Àustria)) ;
Ourselin, Sebastien (University College London Hospitals) ;
Gandini Wheeler-Kingshott, Claudia A. M (IRCCS Mondino Foundation (Pavia, Itàlia)) ;
Chard, Declan (University College London Hospitals) ;
Thompson, Alan J. (University College London. Faculty of Brain Sciences) ;
Barkhof, Frederik (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ;
Alexander, Daniel C.. (University College London. Department of Computer Science) ;
Ciccarelli, Olga (University College London Hospitals) ;
Universitat Autònoma de Barcelona
See Stankoff and Louapre (doi:) for a scientific commentary on this article. Grey matter atrophy in multiple sclerosis affects certain areas preferentially. Eshaghi et al. use a data-driven computational model to predict the order in which regions atrophy, and use this sequence to stage patients. [...]
2018 - 10.1093/brain/awy088
Brain, Vol. 141 (may 2018) , p. 1665-1677
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15 p, 853.5 KB |
ESHRE Clinical Embryologist certification : the first 10 years
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Kovačič, Borut (University Medical Centre Maribor) ;
Prados, Fernando J. ;
Plas, Catherine (ESHRE Central Office) ;
Woodward, Bryan J. (X&Y Fertility) ;
Verheyen, Greta (Vrije Universiteit Brussel) ;
Ramos, Liliana (Radboud University Medical Centre) ;
Mäkinen, Sirpa (Ovumia Fertinova) ;
Apter, Susanna Jamina (Livio Fertilitetscentrum) ;
Vidal, Francesca (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ziebe, Søren (University of Copenhagen) ;
Magli, M. Cristina (SISMER) ;
Lundin, Kersti (Sahlgrenska University Hospital (Suècia)) ;
Sunde, Arne (Norwegian University of Science and Technology) ;
Plancha, Carlos E. (Universidade de Lisboa)
What has the ESHRE programme 'ESHRE Certification for Clinical Embryologists' achieved after 10 years? The post-exam analysis showed a pass rate of 60% for Clinical and 50% for Senior Clinical Embryologists and a high level of internal consistency of all exams, leading to a total of 773 certified Clinical and 493 Senior Clinical Embryologists over the decade. [...]
2020 - 10.1093/hropen/hoaa026
Human Reproduction Open, Vol. 2020, Issue 3 (July 2020) , Art. hoaa026
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9 p, 634.6 KB |
Bullseye's representation of cerebral white matter hyperintensities
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Sudre, Carol H. (Dementia Research Centre, UCL Institute of Neurology, WC1N 3BG London, UK) ;
Gómez-Ansón, Beatriz (Institut d'Investigació Biomèdica Sant Pau) ;
Davagnanam, Indran (University College London. Institute of Neurology) ;
Schmitt, Anne Jutta (Lysholm Department of Neuroradiology, The National Hospital for Neurology and Neurosurgery, Queen Square, WCN1 3BG London, UK) ;
Mendelson, Alex F. (Translational Imaging Group, University College London, UK) ;
Prados Carrasco, Ferran (Translational Imaging Group, CMIC, University College London, UK) ;
Smith, Lorna (Institute of Cardiovascular Science (Londres, Regne Unit)) ;
Atkinson, David (University College London. Centre for Medical Image) ;
Hughes, Alun D. (Institute of Cardiovascular Science (Londres, Regne Unit)) ;
Chaturvedi, Nish R. (Institute of Cardiovascular Science (Londres, Regne Unit)) ;
Cardoso, jorge Jorge (Dementia Research Centre, UCL Institute of Neurology, London, UK) ;
Barkhof, Frederik (University College London. Institute of Neurology) ;
Rolf Jaeger, H. (University College London. Institute of Neurology) ;
Ourselin, Sebastien (Dementia Research Centre, UCL Institute of Neurology, London, UK) ;
Universitat Autònoma de Barcelona
Visual rating scales have limited capacities to depict the regional distribution of cerebral white matter hyperintensities (WMH). We present a regional-zonal volumetric analysis alongside a visualization tool to compare and deconstruct visual rating scales. [...]
2018 - 10.1016/j.neurad.2017.10.001
Journal of Neuroradiology. Journal De Neuroradiologie, Vol. 45 (march 2018) , p. 114-122
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7.
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13 p, 862.2 KB |
Deep gray matter volume loss drives disability worsening in multiple sclerosis
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Eshaghi, Arman (University College London) ;
Prados Carrasco, Ferran (University College London Hospitals) ;
Brownlee, Wallace J. (University College London) ;
Altmann, Daniel R. (London School of Hygiene & Tropical Medicine) ;
Tur, Carmen (University College London) ;
Cardoso, M. Jorge (University College London) ;
De Angelis, Floriana (University College London) ;
van de Pavert, Steven H. (University College London) ;
Cawley, Niamh (University College London) ;
De Stefano, Nicola (University of Siena) ;
Stromillo, M. Laura (University of Siena) ;
Battaglini, Marco (University of Siena) ;
Ruggieri, Serena (University of Rome Sapienza) ;
Gasperini, Claudio (San Camillo Forlanini Hospital) ;
Filippi, Massimo (Vita-Salute San Raffaele University) ;
Rocca, Maria A. (Vita-Salute San Raffaele University) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron) ;
Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ;
Vrenken, Hugo (VU University Medical Centre) ;
Leurs, Cyra E. (Amsterdam UMC. University Medical Center) ;
Killestein, Joep (Amsterdam UMC. University Medical Center) ;
Pirpamer, Lukas (Medical University of Graz) ;
Enzinger, Christian (Medical University of Graz) ;
Ourselin, Sebastien (University College London Hospitals) ;
Wheeler-Kingshott, Claudia A. M. Gandini (C. Mondino National Neurological Institute) ;
Chard, Declan (University College London Hospitals) ;
Thompson, Alan J. (University College London) ;
Alexander, Daniel C.. (University College London) ;
Barkhof, Frederik (VU University Medical Centre) ;
Ciccarelli, Olga (University College London Hospitals) ;
Universitat Autònoma de Barcelona
Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with faster disability accumulation in MS. [...]
2018 - 10.1002/ana.25145
Annals of neurology, Vol. 83, Issue 2 (February 2018) , p. 210-222
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