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9 p, 1.0 MB |
Improved survival after acute graft-versus-host disease diagnosis in the modern era
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Khoury, Hanna J. (Winship Cancer Institute of Emory University) ;
Wang, Tao (Medical College of Wisconsin) ;
Hemmer, Michael T. (Medical College of Wisconsin) ;
Couriel, Daniel (Utah Blood and Marrow Transplant) ;
Alousi, Amin (The University of Texas MD Anderson Cancer Center) ;
Cutler, Corey (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Battiwalla, Minoo (Lung and Blood Institute-NIH) ;
Cahn, Jean Yves (University Hospital) ;
Cairo, Mitchell (New York Medical College) ;
Chen, Yi-Bin (Massachusetts General Hospital) ;
Gale, Robert Peter (Imperial College London) ;
Hashmi, Shahrukh (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Hayashi, Robert J. (Washington University School of Medicine in St. Louis) ;
Jagasia, Madan (Vanderbilt University Medical Center) ;
Juckett, Mark (University of Wisconsin Hospital and Clinics) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Kharfan-Dabaja, Mohamed (H. Lee Moffitt Cancer Center and Research Institute) ;
Litzow, Mark (Mayo Clinic Rochester) ;
Majhail, Navnnet (Cleveland Clinic Taussig Cancer Institute) ;
Miller, Alan (Baylor College of Medicine) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center and Research Institute) ;
Qayed, Muna (Emory University School of Medicine) ;
Antin, Joseph H. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Schoemans, Helene (University Hospitals Leuven (Bèlgica)) ;
Schouten, Harry C. (Academische Ziekenhuis) ;
Socie, Gerard (Hopital Saint Louis) ;
Storek, Jan (University of Calgary) ;
Verdonck, Leo (Isala Clinics Zwolle) ;
Vij, Ravi (Washington University School of Medicine) ;
Wood, Willian A. (University of North Carolina) ;
Yu, Lolie (Children's Hospital/Louisiana State University Medical Center) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Carabasi, Matthew (Thomas Jefferson University Hospital) ;
Dandoy, Christopher (Cincinnati Children's Hospital Medical Center) ;
Gergis, Usama (New York Presbyterian Hospital/Weill Cornell Medical Center) ;
Hematti, Peiman (University of Wisconsin Hospital and Clinics) ;
Solh, Melham (The Blood and Marrow Transplant Group of Georgia) ;
Jamani, Kareem (University of Calgary) ;
Lehmann, Leslie (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Savani, Bipin (Vanderbilt University Medical Center) ;
Schultz, Kirk R. (The University of British Columbia) ;
Wirk, Baldeep M. (Seattle Cancer Care Alliance) ;
Spellman, Stephen (Center for International Blood and Marrow Transplant Research) ;
Arora, Mukta (University of Minnesota Medical Center) ;
Pidala, Joseph (H. Lee Moffitt Cancer Center and Research Institute) ;
Universitat Autònoma de Barcelona
Acute graft-versus-host disease remains a major threat to a successful outcome after allogeneic hematopoietic cell transplantation. While improvements in treatment and supportive care have occurred, it is unknown whether these advances have resulted in improved outcome specifically among those diagnosed with acute graft-versus-host disease. [...]
2017 -  10.3324/haematol.2016.156356
Haematologica, Vol. 102 Núm. 5 (30 2017) , p. 958-966
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9 p, 406.9 KB |
Impact of T Cell Dose on Outcome of T Cell-Replete HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation
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Saad, Ayman (The Ohio State University) ;
Lamb, Lawrence (University of Alabama at Birmingham) ;
Wang, Tao (Medical College of Wisconsin) ;
Hemmer, Michael T. (Medical College of Wisconsin) ;
Spellman, Stephen (National Marrow Donor Program/Be the Match) ;
Couriel, Daniel R (Utah Blood and Marrow Transplant Program) ;
Alousi, Amin (Anderson Cancer Center) ;
Pidala, Joseph (H. Lee Moffitt Cancer Center) ;
Abdel-Azim, Hisham (University of Southern California Keck School of Medicine) ;
Agrawal, Vaibhav (Indiana University School of Medicine) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Beitinjaneh, Amer (University of Miami) ;
Bhatt, Vijaya Raj (University of Nebraska Medical Center) ;
Buchbinder, David Kyle (Children's Hospital of Orange County) ;
Byrne, Michael (Vanderbilt University Medical Center) ;
Cahn, Jean-Yves (CHU Grenoble Alpes) ;
Cairo, Mitchell S. (New York Medical College) ;
Castillo, Paul A. (UF Health Shands Children's Hospital) ;
Chhabra, Saurabh (Medical College of Wisconsin) ;
Diaz, Miguel Angel (Hospital Infantil Universitario Nino Jesus) ;
Farhan, Shatha (Henry Ford Hospital Bone Marrow Transplant Program) ;
Floisand, Yngvar (The National Hospital) ;
Frangoul, Haydar A. (Children's Hospital at TriStar Centennial and Sarah Cannon Research Institute) ;
Gadalla, Shahinaz M. (National Cancer Institute) ;
Gajewski, James (Consultant at Lu Daopei Hospital) ;
Gale, Robert Peter (Imperial College London) ;
Gandhi, Manish (Mayo Clinic) ;
Gergis, Usama (New York Presbyterian Hospital/Weill Cornell Medical Center) ;
Hamilton, Betty (Cleveland Clinic Taussig Cancer Institute) ;
Hematti, Peiman (University of Wisconsin Hospital and Clinics) ;
Hildebrandt, Gerhard C. (University of Kentucky) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Kanate, Abraham S. (West Virginia University) ;
Khandelwal, Pooja (Cincinnati Children's Hospital Medical Center) ;
Lazaryn, Aleksandr (H. Lee Moffitt Cancer Center) ;
MacMillan, Margaret (University of Minnesota Blood and Marrow Transplant Program) ;
Marks, David I. (University Hospitals Bristol NHS Trust) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Mehta, Parinda A. (Cincinnati Children's Hospital Medical Center) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center) ;
Olsson, Richard (Uppsala University) ;
Patel, Sagar (Cleveland Clinic Foundation) ;
Qayed, Muna (Emory University School of Medicine) ;
Rangarajan, Hemalatha G. (Nationwide Children's Hospital) ;
Reshef, R. (Columbia University Medical Center) ;
Ringden, O. (Karolinska Institutet (Estocolm, Suècia)) ;
Savani, B.N. (Vanderbilt University Medical Center) ;
Schouten, H.C. (Academische Ziekenhuis) ;
Schultz, K.R. (The University of British Columbia) ;
Seo, S. (Dokkyo Medical University) ;
Shaffer, B.C. (Memorial Sloan Kettering Cancer Center) ;
Solh, M. (Northside Hospital) ;
Teshima, T. (Hokkaido University Hospital) ;
Urbano-Ispizua, Alvaro (Hospital Clínic i Provincial de Barcelona) ;
Verdonck, L.F. (Isala Clinic) ;
Vij, R. (Washington University School of Medicine) ;
Waller, E.K. (Emory University) ;
William, B. (The Ohio State University) ;
Wirk, B. (Seattle Cancer Care Alliance) ;
Yared, J.A. (University of Maryland) ;
Yu, L.C. (Children's Hospital/Louisiana State University Medical Center) ;
Arora, M. (University of Minnesota Medical Center) ;
Hashmi, S. (Mayo Clinic) ;
Universitat Autònoma de Barcelona
Data on whether the T cell dose of allogeneic peripheral blood stem cell (PBSC) products influences transplantation outcomes are conflicting. Using the Center for International Blood and Marrow Transplant Research database, we identified 2736 adult patients who underwent first allogeneic PBSC transplantation for acute leukemia or myelodysplastic syndrome between 2008 and 2014 using an HLA-matched sibling donor (MSD) or an 8/8-matched unrelated donor (MUD). [...]
2019 - 10.1016/j.bbmt.2019.05.007
Biology of blood and marrow transplantation, Vol. 25 Núm. 9 (september 2019) , p. 1875-1883
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10 p, 523.7 KB |
Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide
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Im, A. (University of Pittsburgh/UPMC Hillman Cancer Center) ;
Rashidi, A. (University of Minnesota) ;
Wang, T. (Medical College of Wisconsin) ;
Hemmer, M. (Medical College of Wisconsin) ;
MacMillan, M.L. (University of Minnesota) ;
Pidala, J. (H. Lee Moffitt Cancer Center and Research Institute) ;
Jagasia, M. (Vanderbilt University Medical Center) ;
Pavletic, S. (National Cancer Institute of Bethesda) ;
Majhail, N.S. (Cleveland Clinic Taussig Cancer Institute) ;
Weisdorf, D. (University of Minnesota) ;
Abdel-Azim, Hisham (University of Southern California Keck School of Medicine) ;
Agrawal, Vaibhav (Indiana University School of Medicine) ;
Al-Homsi, A.S. (New York University Langone Medical Center) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Askar, Medhat (Baylor University Medical Center) ;
Auletta, Jeffery J (Nationwide Children's Hospital) ;
Bashey, A. (Blood and Marrow Transplant Program at Northside Hospital) ;
Beitinjaneh, Amer (University of Miami) ;
Bhatt, Vijaya Raj (University of Nebraska Medical Center) ;
Byrne, M. (Vanderbilt University Medical Center) ;
Cahn, J.Y. (CHU Grenoble Alpes) ;
Cairo, M. (New York Medical College) ;
Castillo, P. (UF Health Shands Children's Hospital) ;
Cerny, J. (University of Massachusetts Medical Center) ;
Chhabra, Saurabh (Medical College of Wisconsin) ;
Choe, H. (The Ohio State University Wexner Medical Center) ;
Ciurea, S. (The University of Texas MD Anderson Cancer Center) ;
Daly, A. (Tom Baker Cancer Center) ;
Perez, M.A.D. (Hospital Infantil Universitario Nino Jesus) ;
Farhadfar, N. (University of Florida College of Medicine) ;
Gadalla, S.M. (NIH-NCI Clinical Genetics Branch) ;
Gale, R. (Imperial College London) ;
Ganguly, S. (University of Kansas Health System) ;
Gergis, U. (Thomas Jefferson University) ;
Hanna, R. (Cleveland Clinic Foundation) ;
Hematti, Peiman (University of Wisconsin) ;
Herzig, R. (University of Kentucky Chandler Medical Center) ;
Hildebrandt, G.C. (University of Kentucky) ;
Lad, D.P. (Postgraduate Institute of Medical Education and Research) ;
Lee, C. (University of Utah) ;
Lehmann, L. (Dana-Farber Cancer Institute/Boston Children's Hospital) ;
Lekakis, L. (University of Miami) ;
Kamble, R.T. (Baylor College of Medicine) ;
Kharfan-Dabaja, M.A. (Mayo Clinic) ;
Khandelwal, P. (University of Cincinnati) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Murthy, H.S. (Mayo Clinic) ;
Nishihori, T. (Moffitt Cancer Center) ;
O'Brien, T.A. (Sydney Children's Hospital) ;
Olsson, R.F. (Uppsala University) ;
Patel, S.S. (University of Utah) ;
Perales, M.A. (Memorial Sloan Kettering Cancer Center) ;
Prestidge, T. (Starship Children's Hospital (Auckland, Nova Zelanda)) ;
Qayed, M. (Emory University School of Medicine) ;
Romee, R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Schoemans, H. (University Hospitals Leuven (Bèlgica)) ;
Seo, S. (Dokkyo Medical University) ;
Sharma, A. (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ;
Solh, M. (Northside Hospital) ;
Strair, R. (Rutgers University) ;
Teshima, T. (Hokkaido University Hospital) ;
Urbano-Ispizua, Alvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Van der Poel, M. (Maastricht University Medical Center) ;
Vij, R. (Washington University School of Medicine) ;
Wagner, J.L. (Thomas Jefferson University) ;
William, B. (The Ohio State University) ;
Wirk, B. (Penn State Cancer Institute) ;
Yared, J.A. (University of Maryland) ;
Spellman, S.R. (Medical College of Wisconsin) ;
Arora, Mukta (University of Minnesota Medical Center) ;
Hamilton, B. K. (Cleveland Clinic Taussig Cancer Institute) ;
Universitat Autònoma de Barcelona
Post-transplant cyclophosphamide (PTCy) has significantly increased the successful use of haploidentical donors with a relatively low incidence of graft-versus-host disease (GVHD). Given its increasing use, we sought to determine risk factors for GVHD after haploidentical hematopoietic cell transplantation (haplo-HCT) using PTCy. [...]
2020 - 10.1016/j.bbmt.2020.05.001
Biology of blood and marrow transplantation, Vol. 26 Núm. 8 (august 2020) , p. 1459-1468
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13 p, 850.9 KB |
Comparative Analysis of Calcineurin Inhibitor-Based Methotrexate and Mycophenolate Mofetil-Containing Regimens for Prevention of Graft-versus-Host Disease after Reduced-Intensity Conditioning Allogeneic Transplantation
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Chhabra, Saurabh (Medical College of Wisconsin) ;
Liu, Ying (Medical College of Wisconsin) ;
Hemmer, Michael T. (Medical College of Wisconsin) ;
Costa, Luciano (University of Alabama at Birmingham. Department of Medicine) ;
Pidala, Joseph A. (H. Lee Moffitt Cancer Center and Research Institute) ;
Couriel, Daniel R. (Utah Blood and Marrow Transplant Program) ;
Alousi, Amin M. (University of Texas MD Anderson Cancer Center) ;
Majhail, Navneet S. (Cleveland Clinic Taussig Cancer Institute) ;
Stuart, Robert K. (Medical University of South Carolina) ;
Kim, Dennis (Princess Margaret Cancer Center) ;
Ringden, Olle (Karolinska Institutet (Estocolm, Suècia). Division of Therapeutic Immunology) ;
Urbano Ispizua, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Saad, Ayman (University of Alabama at Birmingham) ;
Savani, Bipin N. (Vanderbilt University Medical Center) ;
Cooper, Brenda (University Hospitals Case Medical Center. Department of Medicine-Hematology and Oncology) ;
Marks, David I. (University Hospitals Bristol NHS Trust) ;
Socie, Gerard (Hôpital Saint Louis. Department of Hematology) ;
Schouten, Harry C. (Academische Ziekenhuis. Department of Hematology) ;
Schoemans, Helene (University Hospitals Leuven (Bèlgica)) ;
Abdel-Azim, Hisham (University of Southern California Keck School of Medicine) ;
Yared, Jean (University of Maryland. Greenebaum Cancer Center) ;
Cahn, Jean-Yves (CHU Grenoble Alpes. Department of Hematology) ;
Wagner, John (Thomas Jefferson University. Department of Medical Oncology) ;
Antin, Joseph H. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Verdonck, Leo F. (Isala Clinic. Departmentt of Hematology/Oncology) ;
Lehmann, Leslie (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
MacMillan, Margaret L. (University of Minnesota Blood and Marrow Transplant Program) ;
Litzow, Mark R. (Mayo Clinic Rochester. Division of Hematology and Transplant Center) ;
Solh, Melhem M. (Northside Hospital. Blood and Marrow Transplant Group of Georgia) ;
Qayed, Muna (Emory University School of Medicine. Department of Pediatrics) ;
Hematti, Peiman (University of Wisconsin) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Vij, Ravi (Washington University School of Medicine. Division of Hematology and Oncology) ;
Hayashi, Robert J. (Washington University School of Medicine in St. Louis. Division of Pediatric Hematology/Oncology) ;
Gale, Robert Peter (Imperial College London. Hematology Research Centre) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Seo, Sachiko (National Cancer Research Center East) ;
Hashmi, Shahrukh K (Mayo Clinic Rochester. Division of Hematology and Transplant Center) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center and Research Institute) ;
Teshima, Takanori (Kyushu University Hospital) ;
Gergis, Usama (New York Presbyterian Hospital/Weill Cornell Medical Center. Department of Medical Oncology) ;
Inamoto, Yoshihiro (National Cancer Center Hospital) ;
Spellman, Stephen R. (Center for International Blood and Marrow Transplant Research) ;
Arora, Mukta (University of Minnesota Medical Center) ;
Hamilton, Betty K. (Cleveland Clinic Taussig Cancer Institute) ;
Universitat Autònoma de Barcelona
The combination of a calcineurin inhibitor (CNI) such as tacrolimus (TAC) or cyclosporine (CYSP) with methotrexate (MTX) or with mycophenolate mofetil (MMF) has been commonly used for graft-versus-host disease (GVHD) prophylaxis after reduced-intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (alloHCT), but there are limited data comparing efficacy of the 2 regimens. [...]
2019 - 10.1016/j.bbmt.2018.08.018
Biology of blood and marrow transplantation, Vol. 25 Núm. 1 (january 2019) , p. 73-85
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