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11 p, 912.1 KB |
Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing
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Corominas, Jordi (Radboud University Medical Center) ;
Klein, Marieke (Radboud University Medical Center) ;
Zayats, Tetyana (University of Bergen) ;
Rivero, Olga (University of Würzburg) ;
Ziegler, Georg C. (University of Würzburg) ;
Pauper, Marc (Radboud University Medical Center) ;
Neveling, Kornelia (Radboud University Medical Center) ;
Poelmans, Geert (Radboud University Medical Center) ;
Jansch, Charline (University of Würzburg) ;
Svirin, Evgeniy (I.M. Sechenov First Moscow State Medical University) ;
Geissler, Julia (University Hospital of Würzburg) ;
Weber, Heike (University Hospital Frankfurt) ;
Reif, Andreas (University Hospital Frankfurt) ;
Arias Vasquez, Alejandro (Radboud University Medical Center) ;
Galesloot, Tessel E. (Radboud University Medical Center) ;
Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ;
Buitelaar, Jan K. (Radboud University Medical Center) ;
Ramos Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Ribasés, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hveem, Kristian (Norwegian University of Science and Technology) ;
Gabrielsen, Maiken Elvestad (Norwegian University of Science and Technology) ;
Hoffmann, Per (University of Basel) ;
Cichon, Sven (University Hospital Basel) ;
Haavik, Jan (Haukeland University Hospital) ;
Johansson, Stefan (University of Bergen) ;
Jacob, Christian P. (University of Würzburg) ;
Romanos, Marcel (University Hospital of Würzburg) ;
Franke, Barbara (Radboud University Medical Center) ;
Lesch, Klaus-Peter (Maastricht University)
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with a complex genetic background, hampering identification of underlying genetic risk factors. We hypothesized that combining linkage analysis and whole-exome sequencing (WES) in multi-generation pedigrees with multiple affected individuals can point toward novel ADHD genes. [...]
2018 -  10.1038/s41380-018-0210-6
Molecular Psychiatry, Vol. 25 (august 2018) , p. 2047-2057
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2.
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10 p, 2.1 MB |
Shared genetic background between children and adults with attention deficit/hyperactivity disorder
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Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Demontis, Ditte (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zayats, Tetyana (Broad Institute of MIT and Harvard) ;
Klein, Marieke (University Medical Center Utrecht) ;
Mota, Nina Roth (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Weber, Heike (University Hospital Frankfurt. Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy) ;
Garcia-Martínez, Iris (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pagerols, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilar-Ribó, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arribas, Lorena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Martin, Gemma Español (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Almos, Peter (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Doyle, Alysa E. (Harvard Medical School. Department of Psychiatry) ;
Grevet, Eugenio Horacio (Universidade Federal do Rio Grande do Sul. Department of Psychiatry, Faculty of Medicine) ;
Grimm, Oliver (University Hospital Frankfurt. Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy) ;
Halmøy, Anne (Haukeland University Hospital. Division of Psychiatry) ;
Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour) ;
Hutz, Mara (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Jacob, Christian P. (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Kittel-Schneider, Sarah (University Hospital Frankfurt. Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy) ;
Knappskog, Per M. (University of Bergen. Department of Clinical Science) ;
Lundervold, Astri J. (University of Bergen. Department of Biological and Medical Psychology) ;
Rivero, Olga (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Rovaris, Diego Luiz (University of São Paulo. Department of Physiology and Biophysics, Institute of Biomedical Sciences) ;
Salatino-Oliveira, Angelica (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
da Silva, Bruna Santos (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Svirin, Evgeniy (IM Sechenov First Moscow State Medical University. Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine) ;
Sprooten, Emma (Radboud University Medical Centre. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour) ;
Strekalova, Tatyana (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Arias-Vasquez, Alejandro (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Sonuga-Barke, Edmund J. S. (Aarhus University. Department of Child and Adolescent Psychiatry) ;
Asherson, Philip (King's College London. Social Genetic and Developmental Psychiatry, Institute of Psychiatry Psychology and Neuroscience) ;
Bau, Claiton Henrique Dotto (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Buitelaar, Jan K. (Karakter Child and Adolescent Psychiatry, Nijmegen, The Netherlands) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Faraone, Stephen V. (SUNY Upstate Medical University. Departments of Psychiatry, of Neuroscience, and Physiology) ;
Haavik, Jan (Haukeland University Hospital. Division of Psychiatry) ;
Johansson, Stefan E. (University of Bergen. Department of Clinical Science) ;
Kuntsi, Jonna (King's College London. Social Genetic and Developmental Psychiatry, Institute of Psychiatry Psychology and Neuroscience) ;
Larsson, Henrik (Karolinska Institutet. Department of Medical Epidemiology and Biostatistics) ;
Lesch, Klaus-Peter (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Reif, Andreas (University Hospital Frankfurt. Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy) ;
Rohde, Luis Augusto (Universidade Federal do Rio Grande do Sul. Hospital de Clinicas de Porto Alegre) ;
Casas, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Børglum, Anders D. (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Franke, Barbara (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by age-inappropriate symptoms of inattention, impulsivity, and hyperactivity that persist into adulthood in the majority of the diagnosed children. [...]
2020 - 10.1038/s41386-020-0664-5
Neuropsychopharmacology, Vol. 45 (april 2020) , p. 1617-1626
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3.
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23 p, 601.7 KB |
Effectiveness of a Transdiagnostic Guided Internet-Delivered Protocol for Emotional Disorders Versus Treatment as Usual in Specialized Care : Randomized Controlled Trial
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González-Robles, Alberto (Universitat Jaume I. Department of Basic and Clinical Psychology, and Psychobiology) ;
Díaz-García, Amanda (Universitat Jaume I. Department of Basic and Clinical Psychology, and Psychobiology) ;
García-Palacios, Azucena (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Roca, Pablo (Universidad Complutense de Madrid. Department of Personality, Assessment, and Clinical Psychology) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Botella, Cristina (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Anxiety disorders and depression (emotional disorders) are highly prevalent mental disorders. Extensive empirical evidence supports the efficacy of cognitive behavioral therapy (CBT) for the treatment of these disorders. [...]
2020 - 10.2196/18220
Journal of medical Internet research, Vol. 22 (july 2020)
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4.
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15 p, 2.4 MB |
ADGRL3 (LPHN3) variants predict substance use disorder
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Arcos-Burgos, Mauricio (Universidad de Antioquia. Instituto de Investigaciones Médicas (IIM), Facultad de Medicina) ;
Vélez, Jorge I. (Universidad del Norte) ;
Martinez, Ariel F. (National Institutes of Health. Medical Genetics Branch, National Human Genome Research Institute) ;
Ribasés, Marta (Hospital Universitari Vall d'Hebron) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Roncero, Carlos (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Fernández-Castillo, Noelia (Institut de Recerca Sant Joan de Déu) ;
Casas, Miguel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Lopera, Francisco (Neuroscience Research Group, Universidad de Antioquia) ;
Pineda, David A. (Neuroscience Research Group, Universidad de Antioquia) ;
Palacio, Juan D. (Neuroscience Research Group, Universidad de Antioquia) ;
Acosta-López, Johan E. (Universidad Simón Bolívar. Grupo de Neurociencias del Caribe, Unidad de Neurociencias Cognitivas) ;
Cervantes-Henriquez, Martha L. (Universidad Simón Bolívar. Grupo de Neurociencias del Caribe, Unidad de Neurociencias Cognitivas) ;
Sánchez-Rojas, Manuel G. (Universidad Simón Bolívar. Grupo de Neurociencias del Caribe, Unidad de Neurociencias Cognitivas) ;
Puentes-Rozo, Pedro J. (Universidad del Atlántico. Grupo de Neurociencias del Caribe) ;
Molina, Brooke S. G. (University of Pittsburg. Departments of Psychiatry and Psychology) ;
Boden, Margaret T. (University of Kentucky Mental Health Research Center at Eastern State Hospital) ;
Wallis, Deeann (Texas A&M University. Department of Biochemistry and Biophysics) ;
Lidbury, Brett (The Australian National University. National Center for Indigenous Genomics, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology and Environment) ;
Newman, Saul (The Australian National University. National Center for Indigenous Genomics, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology and Environment) ;
Easteal, Simon (The Australian National University. National Center for Indigenous Genomics, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology and Environment) ;
Swanson, James (University of California at Irvine. Child Development Center) ;
Patel, Hardip (The Australian National University. Genome Discovery Unit, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology and Environment) ;
Volkow, Nora (National Institutes of Health. Office of the Director, National Institute on Drug Abuse) ;
Acosta, Maria T. (National Institutes of Health. Medical Genetics Branch, National Human Genome Research Institute) ;
Castellanos, Francisco X. (Nathan Kline Institute for Psychiatric Research) ;
de Leon, Jose (University of Kentucky Mental Health Research Center at Eastern State Hospital) ;
Mastronardi, Claudio A. (Universidad del Rosario. Center for Research in Genetics and Genomics, Institute of Translational Medicine, School of Medicine and Health Sciences) ;
Muenke, Maximilian (National Institutes of Health. Medical Genetics Branch, National Human Genome Research Institute)
Genetic factors are strongly implicated in the susceptibility to develop externalizing syndromes such as attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, conduct disorder, and substance use disorder (SUD). [...]
2019 - 10.1038/s41398-019-0396-7
Translational psychiatry, Vol. 9 (january 2019)
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5.
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12 p, 694.9 KB |
Treating impulsivity with probiotics in adults (PROBIA) : study protocol of a multicenter, double-blind, randomized, placebo-controlled trial
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Arteaga-Henríquez, Gara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosales, Silvia Karina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arias-Vásquez, Alejandro (Department of Psychiatry, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands) ;
Bitter, Istvan (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Ginsberg, Ylva (Karolinska Institute. Department of Clinical Neuroscience, Centre for Psychiatry Research) ;
Ibañez-Jimenez, Pol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Kilencz, Tünde (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Lavebratt, Catharina (Karolinska University Hospital. Center for Molecular Medicine (CMM)) ;
Matura, Silke (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Reif, Andreas (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Rethelyi, Janos (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rommelse, Nanda (Karakter Child and Adolescent Psychiatry University Centre) ;
Siegl, Anne (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Impulsivity and compulsivity are related to emotional and social maladjustment and often underlie psychiatric disorders. Recently, alterations in microbiota composition have been shown to have implications for brain development and social behavior via the microbiota-gut-brain axis. [...]
2020 - 10.1186/s13063-019-4040-x
Trials, Vol. 21 (february 2020)
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12 p, 4.0 MB |
Stepwise functional connectivity reveals altered sensory-multimodal integration in medication-naïve adults with attention deficit hyperactivity disorder
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Pretus, Clara (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Marcos-Vidal, Luís. (Departamento de Bioingeniería e Ingeniería Aeroespacial. Universidad Carlos III) ;
Martínez-García, Magdalena. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Picado, Marisol. (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Ramos-Quiroga, Josep Antoni. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Richarte, Vanesa. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castellanos, Francisco X. (Division of Child and Adolescent Psychiatric Research. Nathan Kline Institute for Psychiatric Research) ;
Sepulcre, Jorge. (Harvard Medical School) ;
Desco, Manuel. (Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Vilarroya, Óscar (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Carmona, Susana. (Departamento de Bioingeniería e Ingeniería Aeroespacial. Universidad Carlos III)
Neuroimaging studies indicate that children with attention-deficit/hyperactivity disorder (ADHD) present alterations in several functional networks of the sensation-to-cognition spectrum. These alterations include functional overconnectivity within sensory regions and underconnectivity between sensory regions and neural hubs supporting higher order cognitive functions. [...]
2019 - 10.1002/hbm.24727
Human brain mapping, Vol. 40 Núm. 16 (january 2019) , p. 4645-4656
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42 p, 3.3 MB |
Clinical validation of eye vergence as an objective marker for diagnosis of ADHD in children
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Varela Casal, Paloma (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Esposito, Flavia Lorena (Universitat de Barcelona) ;
Morata Martínez, Imanol (Universitat Politècnica de Catalunya) ;
Capdevila, Alba (Hospital de Mataró) ;
Solé Puig, Maria (Universitat de Barcelona) ;
Osa, Nuria de la (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Ezpeleta, L. (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Perera Lluna, Alexandre (Universitat Politècnica de Catalunya) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Supèr, Hans (Universitat de Barcelona) ;
Cañete, Jose (Hospital de Mataró)
Objective: ADHD youth show poor oculomotor control. Recent research shows that attention-related eye vergence is weak in ADHD children. Method: To validate vergence as a marker to classify ADHD, we assessed the modulation in the angle of vergence of children (n = 43) previously diagnosed with ADHD while performing an attention task and compared the results with age-matched clinical controls (n = 19) and healthy peers (n = 30). [...]
2018 - 10.1177/1087054717749931
Journal of attention disorders, 2018
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6 p, 285.2 KB |
Early developmental, temperamental and educational problems in 'substance use disorder' patients with and without ADHD. Does ADHD make a difference?
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Skutle, Arvid (Bergen Clinics Foundation, Bergen, Norway) ;
Bu, Eli Torild Hellandsjø (Bergen Clinics Foundation, Bergen, Norway) ;
Jellestad, Finn Konow (Department of Biological and Medical Psychology, University of Bergen, Norway) ;
van Emmerik-van Oortmerssen, Katelijne (The Netherlands Arkin, Amsterdam, The Netherlands) ;
Dom, Geert (Collaborative Antwerp Psychiatry Research Institute (CAPRI, UA), PC Alexian Brothers, Boechout, Belgium) ;
Verspreet, Sofie (Collaborative Antwerp Psychiatry Research Institute (CAPRI, UA), PC Alexian Brothers, Boechout, Belgium) ;
Carpentier, Pieter Jan (Reinier van Arkel groep, 's-Hertogenbosch, The Netherlands) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Franck, Johan (Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden) ;
Konstenius, Maija (Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden) ;
Kaye, Sharlene (National Drug and Alcohol Research Centre, UNSW Australia, Sydney, Australia) ;
Demetrovics, Zsolt (Institute of Psychology, Eötvös Loránd University, Budapest, Hungary) ;
Barta, Csaba (Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary) ;
Fatséas, Melina (Laboratoire de psychiatrie Département d'addictologie, Université de Bordeaux, Bordeaux, France) ;
Auriacombe, Marc (Laboratoire de psychiatrie Département d'addictologie, Université de Bordeaux, Bordeaux, France) ;
Johnson, Brian (Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA) ;
Faraone, Stephen V. (Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA) ;
Levin, Frances R. (Columbia University/the New York State Psychiatric Institute, New York, USA) ;
Allsop, Steve (National Drug Research Institute/Curtin University of Technology, Perth, Australia) ;
Carruthers, Susan (National Drug Research Institute/Curtin University of Technology, Perth, Australia) ;
Schoevers, Robert A. (Dept of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands) ;
Koeter, Maarten W.J. (Amsterdam UMC. University Medical Center) ;
van den Brink, Wim (Amsterdam UMC. University Medical Center) ;
Moggi, Franz (University Hospital of Psychiatry, University of Bern, Bern, Switzerland) ;
Møller, Merete (Sykehuset Østfold, Norway) ;
van de Glind, Geurt (Trimbos Instituut, ICASA Foundation, The Netherlands) ;
Universitat Autònoma de Barcelona
The prevalence of ADHD among patients with substance use disorder (SUD) is substantial. This study addressed the following research questions: Are early developmental, temperamental and educational problems overrepresented among SUD patients with ADHD compared to SUD patients without ADHD? Do this comorbid group receive early help for their ADHD, and are there signs of self-medicating with illicit central stimulants? An international, multi-centre cross-sectional study was carried out involving seven European countries, with 1205 patients in treatment for SUD. [...]
2015 - 10.1016/j.abrep.2015.03.001
Addictive Behaviors Reports, Vol. 2 (march 2015) , p. 13-18
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10 p, 533.9 KB |
Health care and societal costs of the management of children and adolescents with attention-deficit/hyperactivity disorder in Spain : a descriptive analysis
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Quintero, Javier (Universidad Complutense de Madrid) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Sebastián, Javier San (Hospital Universitario Ramón y Cajal. Madrid) ;
Montañés, Francisco (Hospital Universitario Fundación de Alcorcón. Madrid) ;
Fernández-Jaén, Alberto (Hospital Universitario Quirón. Madrid) ;
Martínez-Raga, José (Universidad de Valencia.) ;
García Giral, Marta
Institut Clínic de Neurociències (Hospital Clinic, CIBERehd. Department of Pathology) ;
Graell, Montserrat (Hospital Infantil Universitario Niño Jesús. Madrid) ;
Mardomingo, María J. (Hospital General Universitario Gregorio Marañón) ;
Soutullo, César (Clínica Universidad de Navarra) ;
Eiris, Jesús (Complejo Hospitalario Universitario Santiago de Compostela) ;
Téllez, Montserrat (Hospital Universitari i Politècnic La Fe (València)) ;
Pamias, Montserrat (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Correas, Javier (Hospital Universitario del Henares. Madrid) ;
Sabaté, Juncal (Shire. Madrid) ;
García-Orti, Laura (Shire. Madrid) ;
Alda, José A. (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona.
Departament de Psiquiatria i de Medicina Legal
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in childhood (5. 3% to 7. 1% worldwide prevalence), with substantial overall financial burden to children/adolescents, their families, and society. [...]
2018 - 10.1186/s12888-017-1581-y
BMC Psychiatry, Vol. 18 (February 2018) , Núm. 40
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15 p, 2.4 MB |
Genome-wide analyses of aggressiveness in attention-deficit hyperactivity disorder
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Brevik, Erlend J. (Universitetet i Bergen) ;
van Donkelaar, Marjolein M. J. (Donders Institute for Brain, Cognition and Behaviour) ;
Weber, Heike (Goethe Universität Frankfurt am Main. Klinik für Psychiatrie, Psychosomatik und Psychotherapie) ;
Sánchez Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Jacob, Christian (Klinik Nürtingen. Abteilung für Psychiatrie und Psychotherapie) ;
Rivero, Olga (Universität Würzburg. Zentrum fuer Psychische Gesundheit) ;
Kittel-Schneider, Sarah (Universität Würzburg. Zentrum fuer Psychische Gesundheit) ;
Garcia Martínez, Iris (Hospital Universitari Vall d'Hebron) ;
Aebi, Marcel (Psychiatrische Universitätsklinik Zürich) ;
van Hulzen, Kimm (Donders Institute for Brain, Cognition and Behaviour) ;
Cormand, Bru (Universitat de Barcelona. Departament de Genètica) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Lesch, Klaus-Peter (Klinik Nürtingen. Abteilung für Psychiatrie und Psychotherapie) ;
Reif, Andreas (Goethe Universität Frankfurt am Main. Klinik für Psychiatrie, Psychosomatik und Psychotherapie) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Franke, Barbara (Donders Institute for Brain, Cognition and Behaviour) ;
Posserud, Maj-Britt (Universitetet i Bergen) ;
Johansson, Stefan (Haukeland universitetssykehus) ;
Lundervold, Astri J. (Universitetet i Bergen. Senter for nevropsykiatrisk forskning) ;
Haavik, Jan (Universitetet i Bergen) ;
Zayats, Tetyana (Universitetet i Bergen. Senter for nevropsykiatrisk forskning)
Aggressiveness is a behavioral trait that has the potential to be harmful to individuals and society. With an estimated heritability of about 40%, genetics is important in its development. We performed an exploratory genome-wide association (GWA) analysis of childhood aggressiveness in attention deficit hyperactivity disorder (ADHD) to gain insight into the underlying biological processes associated with this trait. [...]
2016 - 10.1002/ajmg.b.32434
American journal of medical genetics, Vol. 171, issue 5 (July 2016) , p. 733-747
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