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15 p, 2.8 MB Deletion of the Gene for the Type I Interferon Inhibitor I329L from the Attenuated African Swine Fever Virus OURT88/3 Strain Reduces Protection Induced in Pigs / Reis, Ana Luisa (The Pirbright Institute (Regne Unit)) ; Goatley, Lynnette C. (The Pirbright Institute (Regne Unit)) ; Jabbar, Tamara (The Pirbright Institute (Regne Unit)) ; López Fernandez, Elisabet (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Rathakrishnan, Anusyah (The Pirbright Institute (Regne Unit)) ; Dixon, Linda K. (The Pirbright Institute (Regne Unit))
Live attenuated vaccines are considered to be the fastest route to the development of a safe and efficacious African swine fever (ASF) vaccine. Infection with the naturally attenuated OURT88/3 strain induces protection against challenge with virulent isolates from the same or closely related genotypes. [...]
2020 - 10.3390/vaccines8020262
Vaccines (Basel), Vol. 8 (may 2020)  

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