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10 p, 787.2 KB |
Granulocytes-Rich Thrombi in Cerebral Large Vessel Occlusion Are Associated with Increased Stiffness and Poorer Revascularization Outcomes
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Juega, Jesus (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Li, Jiahui (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Palacio-Garcia, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez, Maite (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tiberi, Riccardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Piñana, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Tornel, Álvaro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Villatoro, Noelia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rubiera Del Fueyo, Marta A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muchada, Marian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Olivé-Gadea, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rizzo, Federica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernandez, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dios-Lascuevas, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quesada, Helena (Hospital Universitari de Bellvitge) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
De La Torre, Carolina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gallur, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Camacho, Jessica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tomasello, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pagola, Jorge (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
We aim to identify a profile of intracranial thrombus resistant to recanalization by mechanical thrombectomy (MT) in acute stroke treatment. The first extracted clot of each MT was analyzed by flow cytometry obtaining the composition of the main leukocyte populations: granulocytes, monocytes, and lymphocytes. [...]
2023 -  10.1007/s13311-023-01385-1
Neurotherapeutics, Vol. 20 (may 2023) , p. 1167-1176
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12 p, 1.1 MB |
A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype
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Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Cullell, Natalia (Institut d'Investigació Biomèdica Sant Pau) ;
Lledós, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Llucià-Carol, Laia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Sobrino, Tomás (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Campos, Francisco (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Castillo, José (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Freijo, Marimar (Biocruces-Bizkaia Health Research Institute. Department of Neurology) ;
Arenillas, Juan F (Hospital Universitario de Valladolid) ;
Obach, Víctor (Hospital Clínic i Provincial de Barcelona) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Ribó, Marc (Hospital Universitari Vall d'Hebron) ;
Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Roquer, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Muñoz-Narbona, Lucia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López-Cancio, Elena (Hospital Central de Asturias (HUCA)) ;
Millán, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Diaz-Navarro, Rosa (Institut d'Investigació Sanitària Illes Balears) ;
Vives-Bauza, Cristòfol (Institut d'Investigació Sanitària Illes Balears) ;
Serrano-Heras, Gemma (Complejo Hospitalario Universitario de Albacete) ;
Segura, Tomás (Complejo Hospitalario Universitario de Albacete) ;
Ibañez, Laura (Washington University School of Medicine. Department of Psychiatry) ;
Heitsch, Laura (Washington University School of Medicine. Department of Neurology) ;
Delgado, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dhar, Rajat (Washington University School of Medicine. Department of Neurology.) ;
Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Delgado Mederos, Raquel (Institut d'Investigació Biomèdica Sant Pau) ;
Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Camps-Renom, Pol (Institut d'Investigació Biomèdica Sant Pau) ;
Blay, Natalia (Institut Germans Trias i Pujol) ;
Sumoy, Lauro (Institut Germans Trias i Pujol) ;
de Cid, Rafael (Institut Germans Trias i Pujol) ;
Montaner, Joan (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Cruchaga, Carlos (Washington University in St. Louis. Neurogenomics and Informatics Center.) ;
Lee, Jim-Moo (Washington University School of Medicine. Department of Neurology.) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Background: Occult atrial fibrillation (AF) is one of the major causes of embolic stroke of undetermined source (ESUS). Knowing the underlying etiology of an ESUS will reduce stroke recurrence and/or unnecessary use of anticoagulants. [...]
2022 - 10.3389/fcvm.2022.940696
Frontiers in Cardiovascular Medicine, Vol. 9 (august 2022) , p. 940696
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11 p, 946.8 KB |
APRIL : A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
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Hernández-Jiménez, Macarena (AptaTargets (Madrid)) ;
Abad-Santos, Francisco (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cotgreave, Ian (Research Institutes of Sweden) ;
Gallego, Jaime (Neurological Center of Navarra) ;
Jilma, Bernd (Medical University of Vienna) ;
Flores, Alan (Hospital Universitari Joan XXIII de Tarragona) ;
Jovin, Tudor G. (Cooper Neurological Institute) ;
Vivancos, José (Hospital Universitario de la Princesa (Madrid)) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montaner, Joan (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Casariego, Joaquín (Aldebaran Health Intelligence (Madrid)) ;
Dalsgaard, Mads (Cureteq AG) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Liebeskind, David S. (UCLA Stroke Center) ;
Cobo, Erik (Universitat Politècnica de Catalunya. BarcelonaTech) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
In the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). [...]
2023 - 10.3389/fneur.2023.1127585
Frontiers in neurology, Vol. 14 (february 2023)
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6 p, 699.0 KB |
Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study
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de Havenon, Adam (University of Utah) ;
Narata, Ana Paula (University Hospital of Tours) ;
Amelot, Aymeric (Hopital Universitaire Pitie Salpetriere) ;
Saver, Jeffrey L.. (UCLA) ;
Bozorgchami, Hormozd (Oregon Health and Science University) ;
Mattle, Heinrich Paul (University of Bern) ;
Ribo, Marc (Universitat Autònoma de Barcelona) ;
Andersson, Tommy (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Zaidat, Osama (Mercy Health St Vincent Medical Center)
The benefit of endovascular thrombectomy for acute ischemic stroke with M2 segment middle cerebral artery occlusion remains controversial, with uncertainty and paucity of data specific to this population. [...]
2020 - 10.1136/neurintsurg-2020-016427
Journal of Neurointerventional Surgery, Vol. 13 (november 2020) , p. 779-783
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11 p, 623.7 KB |
Stroke etiologies in patients with COVID-19 : the SVIN COVID-19 multinational registry
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Ramos-Araque, María E. (Hospital Clínico Universitario de Valladolid) ;
Siegler, James E. (Cooper University Hospital. Cooper Neurologic Institute) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López, Cristina (Hospital Clínico Universitario de Valladolid) ;
De Lera Alfonso, Mercedes (Hospital Clínico Universitario de Valladolid) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Hernández Pérez, Isabel (Hospital Clínico Universitario de Valladolid) ;
Gómez-Vicente, Beatriz (Hospital Clínico Universitario de Valladolid) ;
Talavera, Blanca (Hospital Clínico Universitario de Valladolid) ;
Portela, Pere Cardona (Hospital Universitari de Bellvitge) ;
Guillen, Ana Nuñez (Hospital Universitari de Bellvitge) ;
Urra, Xabier (Hospital Clínic i Provincial de Barcelona) ;
Llull, Laura (Hospital Clínic i Provincial de Barcelona) ;
Renú, Arturo (Hospital Clínic i Provincial de Barcelona) ;
Nguyen, Thanh N. (Boston University School of Medicin) ;
Jillella, Dinesh (Emory University School of Medicine) ;
Nahab, Fadi (Emory University School of Medicine) ;
Nogueira, Raul (Grady Memorial Hospital) ;
Haussen, Diogo (Grady Memorial Hospital) ;
Then, Ryna (Cooper University Hospital) ;
Thon, Jesse M. (Cooper University Hospital) ;
Esparragoza, Luis Rodríguez (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mansour, Ossama Yassin ;
Megahed, Mohammed (Alexandria University) ;
Hassan, Tamer (Alexandria University) ;
Liebeskind, David S. (Ronald Reagan UCLA Medical Center) ;
Hassan, Ameer E (University of Texas Rio Grande Valley) ;
Bushnaq, Saif (Bon Secours Mercy Health St. Vincent Hospital, Toledo, OH USA) ;
Osman, Mohamed (Bon Secours Mercy Health St. Vincent Hospital, Toledo, OH USA) ;
Vazquez, Alejandro Rodriguez (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Coronavirus disease 2019 (COVID-19) is associated with a small but clinically significant risk of stroke, the cause of which is frequently cryptogenic. In a large multinational cohort of consecutive COVID-19 patients with stroke, we evaluated clinical predictors of cryptogenic stroke, short-term functional outcomes and in-hospital mortality among patients according to stroke etiology. [...]
2021 - 10.1186/s12883-021-02075-1
BMC Neurology, Vol. 21 (january 2021)
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7 p, 310.6 KB |
Health economic impact of first-pass success among patients with acute ischemic stroke treated with mechanical thrombectomy : a United States and European perspective
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Zaidat, Osama (Mercy Saint Vincent Medical Center) ;
Ribo, Marc (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Mattle, Heinrich Paul (University of Bern) ;
Saver, Jeffrey L.. (UCLA) ;
Bozorgchami, Hormozd (Oregon Health and Science University) ;
Yoo, Albert J. (Texas Stroke Institute) ;
Ehm, Alexandra (Johnson & Johnson Medical GmbH) ;
Kottenmeier, Emilie (Cerenovus, Johnson & Johnson) ;
Cameron, Heather L. (EVERSANA) ;
Qadeer, Rana A. (EVERSANA) ;
Andersson, Tommy (Karolinska University Hospital and Karolinska Institutet (Suècia))
First-pass effect (FPE), restoring complete or near complete reperfusion (modified Thrombolysis in Cerebral Infarction (mTICI) 2c-3) in a single pass, is an independent predictor for good functional outcomes in the endovascular treatment of acute ischemic stroke. [...]
2020 - 10.1136/neurintsurg-2020-016930
Journal of Neurointerventional Surgery, Vol. 13 (december 2020) , p. 1117-1123
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10 p, 868.7 KB |
COVID-19 Follow-App. Mobile App-Based Monitoring of COVID-19 Patients after Hospital Discharge : A Single-Center, Open-Label, Randomized Clinical Trial
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Marquez-Algaba, Ester (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sanchez, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Baladas, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
España, Claudia (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Dallo, Hermes Salvatore (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Bibiana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Raventós, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Almirante Gragera, Benito (Instituto de Salud Carlos III) ;
Len, Oscar ((REIPI RD19/0016), Instituto de Salud Carlos III)
Introduction: In the midst of a pandemic, apps can be used to provide close follow-up, ensure that patients are monitored at home, avoid excessive pressure on medical facilities, prevent the movement of people (both patients and health professionals), and reduce the risk of infection. [...]
2022 - 10.3390/jpm12010024
Journal of personalized medicine, Vol. 12 (january 2022)
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11 p, 4.2 MB |
Cerebrovascular events and outcomes in hospitalized patients with COVID-19 : The SVIN COVID-19 Multinational Registry
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Siegler, James E. (Cooper Medical School of Rowan University) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
Arenillas, Juan F.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Megahed, Mohammed (Alexandria University) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jillella, Dinesh (Universitat Autònoma de Barcelona) ;
Talavera, Blanca (Hospital Universitari de Bellvitge) ;
Tiu, Cristina (University Emergency Hospital Bucharest) ;
Terecoasa, Elena O. (University Emergency Hospital Bucharest) ;
Radu, Răzvan A. (Alexandria University) ;
Nguyen, Thanh N. (Boston University School of Medicine) ;
Curiale, Gioacchino ("Carol Davila" University of Medicine and Pharmacy) ;
Kaliaev, Artem (Boston University School of Medicine) ;
Czap, Alexandra L. (Boston University School of Medicine) ;
Sebaugh, Jacob (Boston University School of Medicine) ;
Zha, Alicia M. (Boston University School of Medicine) ;
Liebeskind, David S. (University of Texas Health Science Center) ;
Ortega-Gutierrez, Santiago (Ronald Reagan UCLA Medical Center) ;
Farooqui, Mudassir (Ronald Reagan UCLA Medical Center) ;
Hassan, Ameer E. (Valley Baptist Medical Center) ;
Preston, Laurie (University of Iowa Hospitals and Clinics) ;
Patterson, Mary S. (University of Texas Rio Grande Valley) ;
Bushnaq, Saif (University of Texas Rio Grande Valley) ;
Zaidat, Osama (University of Texas Rio Grande Valley) ;
Jovin, Tudor G. (Cooper Medical School of Rowan University) ;
Universitat Autònoma de Barcelona
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has been associated with a significant risk of thrombotic events in critically ill patients. To summarize the findings of a multinational observational cohort of patients with SARS-CoV-2 and cerebrovascular disease. [...]
2020 - 10.1177/1747493020959216
International Journal of Stroke, september 2020
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15 p, 517.3 KB |
GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke
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Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Nafría, Cristina (Hospital Universitari Vall d'Hebron) ;
Garcia, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Carrera, Caty (Hospital Universitari Vall d'Hebron) ;
Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mútua Terrassa) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Castellanos, María del Mar (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo, Mari Mar (Hospital de Basurto (Bilbao, Biscaia)) ;
Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Rubiera, Marta (Hospital Universitari Vall d'Hebron) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Font, Maria Angels (Hospital Universitari de Bellvitge) ;
Grau Olivares, Marta (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Palomeras, Ernest (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez Zabaleta, Maite (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Masjuan, Jaime (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moniche, Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Piñana, Carlos (Hospital Universitario Virgen de las Nieves (Granada)) ;
Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Cocho, Dolores (Hospital General de Granollers) ;
Navas, Inma (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Tejero, Carlos (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Aymerich, Nuria (Complejo Hospitalario de Navarra) ;
Cullell, Natalia (Fundació Docència i Recerca Mútua Terrassa) ;
Muiño, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubio, Francisco (Hospital Universitari de Bellvitge) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Keene, Keith (Center for Health Disparities. East Carolina University) ;
Chen, Wei-Min (University of Virginia) ;
Worrall, Bradford (University of Virginia) ;
Sale, Michele (Center for Public Health Genomics, University of Virginia) ;
Arboix, Adrià (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron) ;
GRECOSstudy group ;
Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153
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