Results overview: Found 7 records in 0.01 seconds.
Articles, 7 records found
Articles 7 records found  
1.
12 p, 3.2 MB Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli / Rueda, Fabian (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Céspedes, Maria Virtudes (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Seras-Franzoso, Joaquín (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pesarrodona Roches, Mireia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Helmholtz Centre for Infection Research) ; Unzueta, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ; Mamat, Uwe (Airway Research Center North) ; Mangues, Ramon (Institut d'Investigació Biomèdica Sant Pau) ; García Fruitós, Elena (Institut de Recerca i Tecnologia Agroalimentàries) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: production of recombinant drugs in process-friendly endotoxin-free bacterial factories targets to a lessened complexity of the purification process combined with minimized biological hazards during product application. [...]
2016 - 10.1186/s12934-016-0457-z
Microbial cell factories, Vol. 15 (2016) , art. 59  
2.
9 p, 3.4 MB Targeting antitumoral proteins to breast cancer by local administration of functional inclusion bodies / Pesarrodona Roches, Mireia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jauset, Toni (Vall d'Hebron. Institut d'Oncologia) ; Díaz Riascos, Zamira V. (Centro de Investigación Biomédica en Red) ; Sánchez Chardi, Alejandro (Universitat de Barcelona. Departament de Biologia Evolutiva. Ecologia i Ciències Ambientals) ; Beaulieu, Marie Eve (Vall d'Hebron. Institut d'Oncologia) ; Seras-Franzoso, Joaquín (Vall d'Hebron Institut de Recerca) ; Sánchez García, Laura (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Baltà Foix, Ricardo. (Vall d'Hebron Institut de Recerca) ; Mancilla, Sandra (Centro de Investigación Biomédica en Red) ; Fernández, Yolanda (Centro de Investigación Biomédica en Red) ; Rinas, Ursula (Leibniz University of Hannover. Helmholtz Centre for Infection Research) ; Schwartz, Simó (Centro de Investigación Biomédica en Red) ; Soucek, Laura (Vall d'Hebron. Institut d'Oncologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Abasolo, Ibane (Centro de Investigación Biomédica en Red) ; Vázquez Gómez, Esther (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44-targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44 tumor cells in culture, and upon local administration, promote destruction of tumoral tissue in orthotropic mouse models of human breast cancer. [...]
2019 - 10.1002/advs.201900849
Advanced science, Vol. 6, issue 18 (Sep. 2019) , art. 1900849  
3.
5 p, 470.7 KB Packaging protein drugs as bacterial inclusion bodies for therapeutic applications / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; García Fruitós, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Helmholtz-Zentrum für Infektionsforschung) ; Seras-Franzoso, Joaquín (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kosoy, Ana (Janus Development SL) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
A growing number of insights on the biology of bacterial inclusion bodies (IBs) have revealed intriguing utilities of these protein particles. Since they combine mechanical stability and protein functionality, IBs have been already exploited in biocatalysis and explored for bottom-up topographical modification in tissue engineering. [...]
2012 - 10.1186/1475-2859-11-76
Microbial cell factories, Vol. 11 (June 2012) , art. 76  
4.
6 p, 410.5 KB Side effects of chaperone gene co-expression in recombinant protein production / Martínez Alonso, Mónica (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; García Fruitós, Elena (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Leibniz Universität Hannover) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Insufficient availability of molecular chaperones is observed as a major bottleneck for proper protein folding in recombinant protein production. Therefore, co-production of selected sets of cell chaperones along with foreign polypeptides is a common approach to increase the yield of properly folded, recombinant proteins in bacterial cell factories. [...]
2010 - 10.1186/1475-2859-9-64
Microbial cell factories, Vol. 9, Issue 64 (September 2010)  
5.
35 p, 1.1 MB Conformational and functional variants of CD44-targeted protein nanoparticles bio-produced in bacteria. / Pesarrodona Roches, Mireia (Universitat Autònoma de Barcelona. Department de Genètica i de Microbiologia) ; Fernández, Yolanda (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Foradada, Laia (Hospital Vall d'Hebron. CIBBIM-Nanomedicine) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Conchillo-Solé, Oscar (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Unzueta Elorza, Ugutz (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Xu, Zhikun (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Roldán, Mónica (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Villegas Hernández, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Schwartz, Simó (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Rinas, Ursula (Leibniz University of Hannover. Technical Chemistry & Life Science) ; Daura i Ribera, Xavier (Institució Catalana de Recerca i Estudis Avançats) ; Abasolo, Ibane (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Vázquez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Biofabrication is attracting interest as a means to produce nanostructured functional materials because of its operational versatility and full scalability. Materials based on proteins are especially appealing, as the structure and functionality of proteins can be adapted by genetic engineering. [...]
2016
Biofabrication, Vol. 8 Núm 2 (Abril 2016) , p. 25001  
6.
22 p, 421.5 KB Improving protein delivery of fibroblast growth factor-2 from bacterial inclusion bodies used as cell culture substrates / Seras-Franzoso, Joaquín (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Peebo, Karl (Competence Centre of Food And Fermentation Technologies) ; García Fruitós, Elena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Universität Hannover. Institut für Technische Chemie) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Bacterial inclusion bodies (IBs) have recently been used to generate biocompatible cell culture interfaces, with diverse effects on cultured cells such as cell adhesion enhancement, stimulation of cell growth or induction of mesenchymal stem cell differentiation. [...]
2014 - 10.1016/j.actbio.2013.12.021
Acta biomaterialia, Vol. 10 issue 3 (March 2014) , p. 1354-1359  
7.
18 p, 567.4 KB Protein folding and conformational stress in microbial cells producing recombinant proteins : a host comparative overview / Gasser, Brigitte (University of Natural Resources and Life Sciences. Department of Biotechnology (Viena, Àustria)) ; Saloheimo, Markku (VTT Technical Research Centre (Espoo, Finlàndia)) ; Rinas, Ursula (Helmholtz Center for Infection Research (Braunschweig, Alemanya)) ; Dragosits, Martin (University of Natural Resources and Life Sciences. Department of Biotechnology (Viena, Àustria)) ; Rodríguez-Carmona, Escarlata (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Baumann, Kristin (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Giuliani, Maria (University of Naples Federico II. School of Biotechnological Sciences (Nàpols, Itàlia)) ; Parrilli, Ermenegilda (University of Naples Federico II. School of Biotechnological Sciences (Nàpols, Itàlia)) ; Branduardi, Paola (University of Milano-Bicocca. Department of Biotechnology and Bioscience (Milà, Itàlia)) ; Lang, Christine (Technical University Berlin. Institute for Microbiology and Genetics) ; Porro, Danilo (University of Milano-Bicocca. Department of Biotechnology and Bioscience (Milà, Itàlia)) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Tutino, Maria Luisa (University of Naples Federico II. School of Biotechnological Sciences (Nàpols, Itàlia)) ; Mattanovich, Diethard (University of Natural Resources and Life Sciences. Department of Biotechnology (Viena, Àustria)) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Different species of microorganisms including yeasts, filamentous fungi and bacteria have been used in the past 25 years for the controlled production of foreign proteins of scientific, pharmacological or industrial interest. [...]
2008 - 10.1186/1475-2859-7-11
Microbial cell factories, Vol. 7, N. 11 (April 2008) , p. 1-18  

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9 Rinas, Úrsula
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