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11 p, 7.8 MB Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of Group B Streptococcus / Nuccitelli, Annalisa (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Rinaudo, C. Daniela (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Brogioni, Barbara (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Cozzi, Roberta (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Ferrer Navarro, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Yero Corona, Daniel (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Telford, John L. (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Grandi, Guido (Novartis Vaccines and Diagnostics (Siena, Itàlia)) ; Daura i Ribera, Xavier (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Zacharias, Martin (Technical University Munich. Physics Department) ; Maione, Domenico (Novartis Vaccines and Diagnostics (Siena, Itàlia))
The pilus 2a backbone protein (BP-2a) is one of the most structurally and functionally characterized components of a potential vaccine formulation against Group B Streptococcus. It is characterized by six main immunologically distinct allelic variants, each inducing variant-specific protection. [...]
2013 - 10.1371/journal.pcbi.1003115
PLOS Computational Biology, Vol. 9, Issue 6 (June 2013) , p. e1003115  

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1 Rinaudo, C. Daniela
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