Resultados globales: 5 registros encontrados en 0.02 segundos.
Artículos, Encontrados 5 registros
Artículos Encontrados 5 registros  
1.
12 p, 4.8 MB Down syndrome and leukemia : from basic mechanisms to clinical advances / Baruchel, André (Hôpital Universitaire Robert Debré, Paris, France) ; Bourquin, Jean Pierre (University Children's Hospital, Zurich, Switzerland) ; Crispino, John (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ; Cuartero, Sergi (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Hasle, Henrik (Aarhus University Hospital (Aarhus, Dinamarca)) ; Hitzler, Johann (The Hospital for Sick Children, Toronto, Canada) ; Klusmann, Jan Henning (Goethe University Frankfurt, Germany) ; Izraeli, Shai (Tel Aviv University, Tel Aviv, Israel) ; Lane, Andrew A. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Malinge, Sebastien (Cancer Centre, Perth, Western Australia) ; Rabin, Karen R. (University of Oxford, UK) ; Roberts, Irene (University of Oxford, UK) ; Ryeom, Sandra (Columbia University Irving Medical Center, New York, USA) ; Tasian, Sarah K. (University of Pennsylvania Perelman School of Medicine, Philadelphia, USA) ; Wagenblast, Elvin (Icahn School of Medicine at Mount Sinai, New York, USA)
Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been conducted over the last two decades. [...]
2023 - 10.3324/haematol.2023.283225
Haematologica, Vol. 108 Núm. 10 (october 2023) , p. 2570-2581  
2.
15 p, 1.6 MB Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis / Fehmi, Janev (University of Oxford) ; Davies, Alexander J. (University of Oxford) ; Antonelou, Marilina (University College London) ; Keddie, Stephen (National Hospital of Neurology and Neurosurgery (Regne Unit)) ; Pikkupeura, Sonja (University of Oxford) ; Querol, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Delmont, Emilien (Hospital La Timone (França)) ; Cortese, Andrea (University of Pavia) ; Franciotta, Diego (Mondino Foundation) ; Persson, Staffan (Lund University) ; Barratt, Jonathan (University of Leicester) ; Pepper, Ruth (University College London) ; Farinha, Filipa (University College London) ; Rahman, Anisur (University College London) ; Canetti, Diana (University College London) ; Gilbertson, Janet A. (University College London) ; Rendell, Nigel B. (University College London) ; Radunovic, Aleksandar (Royal London Hospital) ; Minton, Thomas (University of Bristol) ; Fuller, Geraint (Gloucestershire Royal Hospital) ; Murphy, Sinead M. (Tallaght University Hospital & Academic Unit of Neurology (Irlanda)) ; Carr, Aisling S. (UCL Institute of Neurology (Regne Unit)) ; Reilly, Mary R. (UCL Institute of Neurology (Regne Unit)) ; Eftimov, Filip (Amsterdam UMC) ; Wieske, Luuk (Amsterdam UMC) ; Teunissen, Charlotte E. (Amsterdam UMC) ; Roberts, Ian S. D. (John Radcliffe Hospital (Regne Unit)) ; Ashman, Neil (The Royal London Hospital (Regne Unit)) ; Salama, Alan D. (University College London Department of Renal Medicine (Regne Unit)) ; Rinaldi, Simon (University of Oxford) ; Universitat Autònoma de Barcelona
Membranous glomerulonephritis (MGN) is a common cause of nephrotic syndrome in adults, mediated by glomerular antibody deposition to an increasing number of newly recognised antigens. Previous case reports have suggested an association between patients with anti-contactin-1 (CNTN1)-mediated neuropathies and MGN. [...]
2023 - 10.1371/journal.pone.0281156
PloS one, Vol. 18 (march 2023)  
3.
14 p, 1.0 MB CD34 + CD19 − CD22 + B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies / Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Barrera, Susana (Universidad de Salamanca) ; Bataller, Alex (Hospital Clínic i Provincial de Barcelona) ; Ortiz-Maldonado, Valentín (Hospital Clínic i Provincial de Barcelona) ; Elliot, Natalina (John Radcliffe Hospital (Oxford, Regne Unit)) ; O'Byrne, Sorcha (John Radcliffe Hospital (Oxford, Regne Unit)) ; Wang, Guanlin (University of Oxford) ; Rovira, Montse (University of Oxford) ; Gutiérrez-Agüera, Francisco (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Trincado Alonso, Juan Luis, 1987- (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; González-González, María (Universidad de Salamanca) ; Morgades, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sorigue, Marc (Universitat Autònoma de Barcelona) ; Bárcena, Paloma (Universidad de Salamanca) ; Zanetti, S. R (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Torrebadell, Montse (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Vega-Garcia, Nerea (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Rives, Susana (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Mallo, Maria del Mar (Universitat Autònoma de Barcelona) ; Sole, F (Universitat Autònoma de Barcelona) ; Mead, Adam J. (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ; Roberts, Irene (Oxford Biomedical Research Centre) ; Thongjuea, Supat (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Psaila, Bethan (Oxford Biomedical Research Centre) ; Juan, Manel (Hospital Clínic i Provincial de Barcelona) ; Delgado, Julio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Urbano-Ispizúa, Alvaro (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ribera, Jose-Maria (Universitat Autònoma de Barcelona) ; Orfao, Alberto (Universidad de Salamanca) ; Roy, Anindita (Oxford Biomedical Research Centre) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Three article in this issue present preclinical data aimed at improving immunotherapeutic approaches for relapsed B- and T-cell acute lymphoblastic leukemia (T-ALL). Chimeric antigen receptor T (CAR-T) cell therapy directed against relapsed T-ALL is hampered by difficulty in identifying a target antigen that is not also expressed on healthy T cells, risking "fratricide" with T-cell aplasia and loss of the CAR-T cells. [...]
2022 - 10.1182/blood.2021014840
Blood, Vol. 140 (july 2022) , p. 38-44  
4.
13 p, 4.7 MB Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis / Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rogers, R. B. (Department of Medicine. University of Cambridge. Cambridge Biomedical Campus) ; Roy, A. (Department of Paediatrics. University of Oxford) ; Schneider, P. (Princess Maxima Center for Pediatric Oncology) ; Bardini, Michela (Università degli Studi di Milano-Bicocca) ; Ballerini, Paola (Pediatric Hematology. A. Trousseau Hospital) ; Cazzaniga, Giovanni (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ; Moreno, T. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Revilla, C. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Gut, Marta (Universitat Pompeu Fabra) ; Valsecchi, M. G. (Interfant Trial Data Center. University of Milano-Bicocca) ; Roberts, I. (MRC Molecular Haematology Unit. MRC Weatherall Institute of Molecular Medicine. University of Oxford) ; Pieters, R. (Princess Maxima Center for Pediatric Oncology) ; De Lorenzo, P. (Interfant Trial Data Center. University of Milano-Bicocca) ; Varela, Ignacio (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Stam, R. W. (Princess Maxima Center for Pediatric Oncology) ; Universitat Autònoma de Barcelona
Bcell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1 (MLL-AF4) infant B-cell acute lymphoblastic leukemia remains difficult to model, and the pathogenic contribution in cancer of the reciprocal fusions resulting from derivative translocated-chromosomes remains obscure. [...]
2019 - 10.3324/haematol.2018.206375
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1176-1188  
5.
17 p, 2.3 MB H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells / Godfrey, L. (University of Oxford. Department of Medicine) ; Crump, N. T. (University of Oxford. Department of Medicine) ; O'Byrne, Sorcha (Department of Paediatrics. University of Oxford) ; Lau, I. J. (University of Oxford. Department of Medicine) ; Rice, S. (University of Oxford. Department of Medicine) ; Harman, J. R. (University of Oxford. Department of Medicine) ; Jackson, T. (Department of Paediatrics. University of Oxford) ; Elliott, N. (Department of Paediatrics. University of Oxford) ; Buck, G. (Department of Paediatrics. University of Oxford) ; Connor, C. (Great Ormond Street Hospital for Children (Londres)) ; Thorne, R. (University of Oxford. Department of Medicine) ; Knapp, D. J. H. F. (MRC Weatherall Institute of Molecular Medicine. Radcliffe Department of Medicine. University of Oxford) ; Heidenreich, O. (Newcastle University. Wolfson Childhood Cancer Research Centre) ; Vyas, P. (Department of Haematology. Oxford University Hospitals NHS Foundation Trust) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Inglott, S. (Great Ormond Street Hospital for Children (Londres)) ; Ancliff, P. (Great Ormond Street Hospital for Children (Londres)) ; Geng, H. (Department of Laboratory Medicine. University of California. San Francisco) ; Roberts, I. (Department of Paediatrics. University of Oxford) ; Roy, A. (Department of Paediatrics. University of Oxford) ; Milne, T. A. (University of Oxford. Department of Medicine) ; Universitat Autònoma de Barcelona
MLL gene rearrangements (MLLr) are a common cause of aggressive, incurable acute lymphoblastic leukemias (ALL) in infants and children, most of which originate in utero. The most common MLLr produces an MLL-AF4 fusion protein. [...]
2021 - 10.1038/s41375-020-0808-y
Leukemia, Vol. 35 Núm. 1 (january 2021) , p. 90-106  

Vea también: autores con nombres similares
1 Roberts, Ian S. D.
2 Roberts, Irene
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