Results overview: Found 4 records in 0.01 seconds.
Articles, 3 records found
Research literature, 1 records found
Articles 3 records found  
1.
15 p, 676.0 KB Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers / Rosás Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz-Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernández, Marco A. (Institut Germans Trias i Pujol) ; Cobarsi, Patricia (Institut Germans Trias i Pujol) ; Crespo, Manel (Complexo Hospitalario Universitario de Vigo) ; Dorrell, Lucy (Nuffield Department of Medicine, University of Oxford,) ; del Romero, Jorge (Centro Sanitario Sandoval, Madrid) ; Alcami, José (Instituto de Salud Carlos III, Madrid) ; Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
A few individuals can control HIV infection without the need for antiretroviral treatment and are referred to as HIV controllers. We have studied HIV controllers who suddenly lose this ability and present with high in vivo viral replication and decays in their CD4 + T-cell counts to identify potential immune and virological factors that were responsible for initial virus control. [...]
2019 - 10.1128/JVI.01436-18
Journal of Virology, Vol. 93 (february 2019)  
2.
12 p, 2.8 MB Gut microbiota linked to sexual preference and HIV infection / Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. IrsiCaixa) ; Guillén, Yolanda (Institut Germans Trias i Pujol. IrsiCaixa) ; Rivera, Javier (Institut Germans Trias i Pujol. IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. IrsiCaixa) ; Nowak, Piotr (Karolinska Universitetssjukhuset) ; Hildebrand, Falk (European Molecular Biology Laboratory) ; Zeller, Georg (European Molecular Biology Laboratory) ; Parera, Mariona (Institut Germans Trias i Pujol. IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. IrsiCaixa) ; Coll, Josep (Institut Germans Trias i Pujol. IrsiCaixa) ; Bravo, Isabel (Hospital Universitari Germans Trias i Pujol) ; Estany, Carla (Hospital Universitari Germans Trias i Pujol) ; Herrero, Cristina (Hospital Universitari Germans Trias i Pujol) ; Saz, Jorge (BCN Checkpoint,) ; Sirera, Guillem (Hospital Universitari Germans Trias i Pujol) ; Torrela, Ariadna (Hospital Universitari Vall d'Hebrón) ; Navarro, Jordi (Hospital Universitari Vall d'Hebrón) ; Crespo, Manel (Hospital Universitari Vall d'Hebrón) ; Brander, Christian (Institut Germans Trias i Pujol. IrsiCaixa) ; Negredo, Eugènia (Universitat de Vic) ; Blanco, Julià (Institut Germans Trias i Pujol. IrsiCaixa) ; Guarner, Francisco (Hospital Universitari Vall d'Hebrón) ; Calle, Maria Luz (Universitat de Vic) ; Bork, Peer (European Molecular Biology Laboratory) ; Sönnerborg, Anders (Karolinska Universitetssjukhuset) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa)
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance following HIV-1 infection, which have not been found in animal models or in studies matched for HIV-1 transmission groups. [...]
2016 - 10.1016/j.ebiom.2016.01.032
EBioMedicine, Vol. 5 (March 2016) , p. 135-146  
3.
23 p, 3.3 MB A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques / Mothe Pujadas, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hu, Xintao (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosati, Margherita (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kulkarni, Viraj (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Valentin, Antonio (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Alicea, Cándido (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Pilkington, Guy R. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Sardesai, Niranjan Y. (Inovio Pharmaceuticals) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Crespo, Manel (Hospital Universitari Vall d'Hebron) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Marco, Andrés (Centre Penitenciari d'Homes (Barcelona, Catalunya)) ; Mullins, James I. (University of Washington (Estats Units d'Amèrica)) ; Dorrell, Lucy (John Radcliffe Hospital (Oxford, Regne Unit)) ; Hanke, Tomáš (University of Oxford (Regne Unit)) ; Clotet i Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pavlakis, George N. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Felber, Barbara K. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
BACKGROUND: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been suboptimal T cell immunogen designs. [...]
2015 - 10.1186/s12967-015-0392-5
Journal of translational medicine, Vol. 13 Núm. 60 (february 2015)  

Research literature 1 records found  
1.
135 p, 4.5 MB Gut microbiome in HIV-1 infection / Rocafort Juncà, Muntsa, autor. ; Paredes i Deiros, Roger, supervisor acadèmic. ; Noguera i Julian, Marc, supervisor acadèmic. ; Coll Figa, Pedro, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia.
Una vegada el Virus de la Immunodeficiència Humana tipus 1 (en anglès HIV-1) infecta l'organisme hoste es produeix una ràpida i severa destrucció del teixit limfoide associat a tracte gastrointestinal que inclou, entre d'altres, significants pèrdues cel·lulars del sistema immunitari i epitelial de l'hoste. [...]
Soon after Human Immunodeficiency Virus type 1 (HIV-1) infection, a severe and rapid depletion of the gut-associated lymphoid tissue occurs, including significant loss of both, immune and epithelial host cells. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  

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