Results overview: Found 2 records in 0.04 seconds.
Articles, 2 records found
Articles 2 records found  
1.
15 p, 2.1 MB Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif / Molinos-Albert, Luis Manuel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bilbao, Eneritz (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Agulló, Luis (Universitat de Vic. Departament de Biociències) ; Marfil, Silvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; García, Elisabet (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, Maria Luisa (Institut Germans Trias i Pujol) ; Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Nieto-Garai, Jon A. (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Contreras, F. Xabier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Floor, Martin (Universitat de Vic. Departament de Biociències) ; Cardona, Pere J. (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Villà-Freixa, Jordi (Universitat de Vic. Departament de Biociències) ; Lorizate, Maier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The HIV-1 gp41 Membrane Proximal External Region (MPER) is recognized by broadly neutralizing antibodies and represents a promising vaccine target. However, MPER immunogenicity and antibody activity are influenced by membrane lipids. [...]
2017 - 10.1038/srep40800
Scientific Reports, gener 2017, p. 1-15  
2.
18 p, 1.7 MB Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals / Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Molinos-Albert, Luis Manuel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, Maria Luisa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Marfil, Silvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; García, Elisabet (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Derking, Ronald (University of Amsterdam) ; Sanders, Rogier W. (University of Amsterdam) ; Clotet i Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco Arbués, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their elicitation may be an interesting goal for any vaccination strategy. [...]
2015 - 10.1371/journal.pone.0120648
PLoS One, Vol. 10, No. 3 (March 2015) , p. e0120648  

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