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5 p, 653.8 KB |
Bone marrow clonogenic myeloid progenitors from NPM1-mutated AML patients do not harbor the NPM1 mutation : Implication for the cell-of-origin of NPM1+ AML
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Díaz de la Guardia, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
González-silva, L. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ;
López-Millán, Belén (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Rodríguez-Sevilla, Juan José (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Baroni, Matteo L. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Anguita, E. (Hematology and hemotherapy Department. Hospital Clínico San Carlos. IMDL. IdISSC. Departamento de Medicina. Universidad Complutense de Madrid) ;
Vives Polo, Susana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Palomo Sanchís, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Lapillonne, H. (Sorbonne Université. INSERM. Centre de recherche Saint-Antoine CRSA. AP-HP. Hôspital Armand Trousseau. Haematology Laboratory) ;
Varela, I. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ;
Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona
The cell-of-origin of NPM1- and FLT3-mutated acute myeloid leukemia (AML) is still a matter of debate. Here, we combined in vitro clonogenic assays with targeted sequencing to gain further insights into the cell-of-origin of NPM1 and FLT3-ITD-mutated AML in diagnostic bone marrow (BM) from nine NPM1+/FLT3-ITD (+/−) AMLs. [...]
2020 -  10.3390/genes11010073
Genes, Vol. 11 Núm. 1 (2020) , p. 73
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28 p, 8.1 MB |
Los pastos de montaña de la Sierra del Aramo (Macizo Central Asturiano) : análisis geoecológico, evolución histórica y dinámica reciente
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Beato Bergua, Salvador (Universidad de Oviedo. Departamento de Geografía) ;
Marino Alfonso, José Luis (Universidad de Oviedo. Departamento de Geografía) ;
Poblete Piedrabuena, Miguel Ángel (Universidad de Oviedo. Departamento de Geografía) ;
Cunill Artigas, Raquel ;
Rodríguez Berdasco, José Manuel
Se analizan los pastizales montanos y subalpinos de la Sierra del Aramo, bastión calcáreo del Macizo Central Asturiano, centrándose no solo en el estado y la composición de las formaciones pratenses, sino también en su origen y devenir histórico, especialmente en la dinámica actual. [...]
S'analitzen les pastures montanes i subalpines de la Serra de l'Aramo, bastió calcari del Massís Central Asturià, centrant-se no només en l'estat i la composició dels prats, sinó també en el seu origen i esdevenir històric, especialment en la dinàmica actual. [...]
This article analyzes the montane and subalpine grasslands of the Sierra del Aramo, a limestone bastion of the Asturian Central Massif. The study focuses not only on the state and composition of the pasture formations, but also on their origin and historical evolution, especially in the current dynamics. [...]
Les prairies montagnardes et subalpines de la Sierra del Aramo, bastion calcaire du Massif Central Asturien, sont analysées en se focalisant non seulement sur l'état et la composition des formations prariales, mais aussi sur leur origine et leur évolution historique, en particulier dans la dynamique actuelle. [...]
2021 - 10.5565/rev/dag.654
Documents d'anàlisi geogràfica, Vol. 67 Núm. 1 (2021) , p. 5-32 (Articles)
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25 p, 7.7 MB |
La Itálica de Adriano. Resultados de las prospecciones arqueológicas de 1991 y 1993
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Rodríguez Hidalgo, José Manuel (Junta de Andalucía. Consejería de Cultura) ;
Keay, Simon J. (University of Southampton) ;
Jordan, David ;
Creighton, J. (University of Reading) ;
Rodà, Isabel, 1948- (Universitat Autònoma de Barcelona. Departament de Ciències de l'Antiguitat i de l'Edat Mitjana)
La prospección geofísica y la recolección sistemática de materiales de superficie dentro de áreas no excavadas de Itálica han puesto al descubierto las plantas de edificios, ahora enterrados, en la Nova Urbs, así como datos sobre su cronología y decoración. [...]
A geographical survey and the systematic collection of surface materials within unexcavated parts of Italica has revealed the discovery of plans of hitherto buried buildings in the Nova Urbs, as well as evidence about their chronology and decoration. [...]
1999 - 10.3989/aespa.1999.v72.297
Archivo español de arqueología, Vol. 72 (1999) , p. 73-97
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8 p, 2.1 MB |
Impact of cytomegalovirus infection on B cell differentiation and cytokine production in multiple sclerosis
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Zabalza, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vera, Andrea (Institut Hospital del Mar d'Investigacions Mèdiques(IMIM). Neurology Department) ;
Alari-Pahissa, Elisenda (Universitat Pompeu Fabra) ;
Munteis, Elvira (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Moreira, Antía (Althaia, Xarxa Assistencial i Universitària de Manresa. Neurology Department) ;
Yélamos, Jose (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Llop, Mireia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
López-Botet, Miguel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Martínez-Rodríguez, Jose E. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Human cytomegalovirus (HCMV) infection has been recently associated with a low risk of multiple sclerosis (MS), yet the basis behind this observation remains uncertain. In this study, we aimed to determine in MS patients whether HCMV induces modifications in the peripheral B cell compartment. [...]
2020 - 10.1186/s12974-020-01840-2
Journal of neuroinflammation, Vol. 17 (may 2020)
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Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease
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Siedlecki-Wullich, Dolores (Universitat Autònoma de Barcelona. Institut de Neurociències (INc)) ;
Català-Solsona, Judit (Universitat Autònoma de Barcelona. Institut de Neurociències (INc)) ;
Fábregas, Cristina (Universitat Autònoma de Barcelona. Institut de Neurociències (INc)) ;
Hernández, Isabel (Universitat Internacional de Catalunya. Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurociències Aplicades) ;
Clarimon, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Boada, Merce (Universitat Internacional de Catalunya. Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurociències Aplicades) ;
Saura, Carlos A. (Universitat Autònoma de Barcelona. Institut de Neurociències (INc)) ;
Rodríguez Álvarez, José (Universitat Autònoma de Barcelona. Institut de Neurociències (INc)) ;
Miñano-Molina, Alfredo J. (Universitat Autònoma de Barcelona. Institut de Neurociències (INc))
Several evidences suggest that failure of synaptic function occurs at preclinical stages of Alzheimer's disease (AD) preceding neuronal loss and the classical AD pathological hallmarks. Nowadays, there is an urgent need to identify reliable biomarkers that could be obtained with non-invasive methods to improve AD diagnosis at early stages. [...]
2019 - 10.1186/s13195-019-0501-4
Alzheimer's research & therapy, Vol. 11 (may 2019)
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Great ape genetic diversity and population history
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Prado-Martinez, J. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Sudmant, P.H. (Department of Genome Sciences. University of Washington) ;
Kidd, J.M. (Department of Genetics. Stanford University) ;
Li, H. (Department of Genetics. Harvard Medical School, Boston) ;
Kelley, J.L. (Department of Genetics. Stanford University) ;
Lorente-Galdos, B. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Veeramah, K.R. (Arizona Research Laboratories. Division of Biotechnology. University of Arizona) ;
Woerner, A.E. (Arizona Research Laboratories. Division of Biotechnology. University of Arizona) ;
O'Connor, T.D. (Department of Genome Sciences. University of Washington) ;
Santpere, G. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Cagan, A. (Department of Evolutionary Genetics. Max Planck Institute for Evolutionary Anthropology) ;
Theunert, C. (Department of Evolutionary Genetics. Max Planck Institute for Evolutionary Anthropology) ;
Casals, F. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Laayouni, H. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Munch, K. (Bioinformatics Research Centre. Aarhus University) ;
Hobolth, A. (Bioinformatics Research Centre. Aarhus University) ;
Halager, A.E. (Bioinformatics Research Centre. Aarhus University) ;
Malig, M. (Department of Genome Sciences. University of Washington) ;
Hernández Rodríguez, José (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Hernando-Herraez, I. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Prüfer, K. (Department of Evolutionary Genetics. Max Planck Institute for Evolutionary Anthropology) ;
Pybus, M. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Johnstone, L. (Arizona Research Laboratories. Division of Biotechnology. University of Arizona) ;
Lachmann, M. (Department of Evolutionary Genetics. Max Planck Institute for Evolutionary Anthropology) ;
Alkan, C. (Bilkent University. Faculty of Engineering) ;
Twigg, D. (Department of Human Genetics. University of Michigan) ;
Petit, N. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Baker, C. (Department of Genome Sciences. University of Washington) ;
Hormozdiari, F. (Department of Genome Sciences. University of Washington) ;
Fernandez-Callejo, M. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Dabad, M. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Wilson, M.L. (Department of Anthropology. University of Minnesota) ;
Stevison, L. (Institute for Human Genetics. University of California San Francisco) ;
Camprubí Sánchez, Cristina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Carvalho, T. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Ruiz-Herrera Moreno, Aurora (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Vives, L. (Department of Genome Sciences. University of Washington) ;
Mele, M. (Centre for Genomic Regulation (CRG)) ;
Abello, Teresa. (Parc Zoològic de Barcelona) ;
Kondova, Ivanela (Biomedical Primate Research Centre) ;
Bontrop, R.E. (Biomedical Primate Research Centre) ;
Pusey, A. (Department of Evolutionary Anthropology. Duke University) ;
Lankester, F. (Paul G. Allen School for Global Animal Health. Washington State University) ;
Kiyang, J.A. (Limbe Wildlife Centre) ;
Bergl, R.A. (North Carolina Zoological Park) ;
Lonsdorf, E. (Department of Psychology. Franklin and Marshall College) ;
Myers, S. (Department of Statistics. Oxford University) ;
Ventura, M. (Department of Genetics and Microbiology. University of Bari) ;
Gagneux, P. (Department of Cellular and Molecular Medicine. University of California San Diego) ;
Comas, D. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Siegismund, H. (Department of Biology, Bioinformatics. University of Copenhagen) ;
Blanc, J. (Centro Nacional de Análisis Genómico (CNAG). PCB) ;
Agueda-Calpena, L. (Centro Nacional de Análisis Genómico (CNAG). PCB) ;
Gut, M. (Centro Nacional de Análisis Genómico (CNAG). PCB) ;
Fulton, L. (Genome Sequencing Center. Washington University School of Medicine) ;
Tishkoff, S.A. (Department of Biology and Genetics. University of Pennsylvania) ;
Mullikin, J.C. (National Institutes of Health Intramural Sequencing Center (NISC)) ;
Wilson, R.K. (Genome Sequencing Center. Washington University School of Medicine) ;
Gut, I.G. (Centro Nacional de Análisis Genómico (CNAG). PCB) ;
Gonder, M.K. (University at Albany - State University of New York www.albany.edu Tradueix aquesta pàgina The University at Albany is the premier public research university in New York's Capital Region and offers more than 17000 students the expansive opportunities ... MyUAlbany Take advantage of the tools that can help you succeed at ... International Admissions Since Sensaburo Kudzo of Japan, the University at Albany's first ... Admissions STRONG PROGRAMS. STRONG STUDENTS. At UAlbany, you'll ... Tour the Campus Join us to learn more about the University at Albany campus ... Academics Academics. In today's evolving world, you need more than the ... Undergraduate Admissions Apply to the University at Albany. Application Instructions for First ... University at Albany) ;
Ryder, O.A. (Genetics Division. San Diego Zoo's Institute for Conservation Research) ;
Hahn, B.H. (Departments of Medicine and Microbiology. Perelman School of Medicine. University of Pennsylvania) ;
Navarro, A. (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ;
Akey, J.M. (Department of Genome Sciences. University of Washington) ;
Bertranpetit, J. (Institut de Biologia Evolutiva. CSIC-Universitat Pompeu Fabra. PRBB) ;
Reich, D. (Department of Genetics. Harvard Medical School, Boston) ;
Mailund, T. (Bioinformatics Research Centre. Aarhus University) ;
Schierup, M.H. (Department of Bioscience. Aarhus University) ;
Hvilsom, C. (Copenhagen Zoo) ;
Andrés, A.M. (Department of Evolutionary Genetics. Max Planck Institute for Evolutionary Anthropology) ;
Wall, J.D. (Institute for Human Genetics. University of California San Francisco) ;
Bustamante, C.D. (Department of Genetics. Stanford University) ;
Hammer, M.F. (Arizona Research Laboratories. Division of Biotechnology. University of Arizona) ;
Eichler, E.E. (Howard Hughes Medical Institute) ;
Marques-Bonet, Tomas. (Institució Catalana de Recerca i Estudis Avançats (ICREA))
Most great ape genetic variation remains uncharacterized; however, its study is critical for understanding population history, recombination, selection and susceptibility to disease. Here we sequence to high coverage a total of 79 wild- and captive-born individuals representing all six great ape species and seven subspecies and report 88. [...]
2013 - 10.1038/nature12228
Nature, Vol. 499, issue 7459 (July 2013) , p. 471-475
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The behavior of Fe in group and acid-treated vermiculite from Santa Olalla, Spain
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Maqueda, Celia (Institute de Recursos Naturales y Agrobiología (CSIC)) ;
Romero, Agua Santas (Institute de Recursos Naturales y Agrobiología (CSIC)) ;
Morillo, Esmeralda (Institute de Recursos Naturales y Agrobiología (CSIC)) ;
Pérez-Rodríguez, José L. (Instituto de Ciencias de Materiales de Sevilla (UNSE-CSIC)) ;
Lerf, Anton (Bayerische Akademie der Wissenschaften. Walther-Meissner-Institut) ;
Wagner, Friedrich Ernst (Technische Universität München. Physik-Department E15)
The preparation of porous materials from clay minerals by selective leaching is of interest because it yields residues with large specific surface areas that can be used as adsorbents of contaminants or as catalysts. [...]
2008 - 10.1346/CCMN.2008.0560307
Clays and Clay Minerals, Vol. 56, Núm. 3 (2008) , p. 380-388
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