Results overview: Found 3 records in 0.02 seconds.
Articles, 3 records found
Articles 3 records found  
1.
13 p, 912.5 KB Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans -Infection Through Recognition of Viral Membrane Gangliosides / Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lorizate, Maier (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodriguez-Plata, Maria T. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Zangger, Nadine (Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland) ; Erikson, Elina (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Pino, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Glass, Bärbel (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Keppler, Oliver T. (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Telenti, Amalio (Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland) ; Kräusslich, Hans-Georg (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Universitat Autònoma de Barcelona
The novel dendritic cell receptor Siglec-1 binds sialyllactose moieties on HIV-1 membrane gangliosides, thereby enhancing HIV-1 transinfection. Dendritic cells (DCs) are essential antigen-presenting cells for the induction of immunity against pathogens. [...]
2012 - 10.1371/journal.pbio.1001448
PLoS biology, Vol. 10 (december 2012)  
2.
16 p, 1.9 MB The infectious synapse formed between mature dendritic cells and CD4 + T cells is independent of the presence of the HIV-1 envelope glycoprotein / Rodriguez-Plata, Maria T (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puigdomènech, Isabel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Since cell-mediated infection of human immunodeficiency virus type 1 (HIV-1) is more efficient than cell-free infection, cell-to-cell propagation plays a crucial role in the pathogenesis of HIV-1 infection. [...]
2013 - 10.1186/1742-4690-10-42
Retrovirology, Vol. 10 (april 2013) , p. 42  
3.
15 p, 1.4 MB Sialyllactose in Viral Membrane Gangliosides Is a Novel Molecular Recognition Pattern for Mature Dendritic Cell Capture of HIV-1 / Izquierdo Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lorizate, Maier (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Contreras, F. Xabier (Heidelberg University Biochemistry Center (BZH), Heidelberg) ; Rodríguez Plata, María T. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Glass, Bärbel (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casas, Josefina (Department of Biomedicinal Chemistry, Institute of Advanced Chemistry of Catalonia (IQAC)/CSIC, Barcelona, Spain) ; Fabriàs, Gemma (Department of Biomedicinal Chemistry, Institute of Advanced Chemistry of Catalonia (IQAC)/CSIC, Barcelona, Spain) ; Kräusslich, Hans Georg (Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany) ; Martínez Picado, Francisco Javier (Institució Catalana de Recerca i Estudis Avançats (ICREA))
An accessible sialyllactose moiety on viral membrane gangliosides is shown to be essential for HIV-1 uptake into mature dendritic cells, thereby promoting viral transfer and infection of bystander CD4+ T lymphocytes. [...]
2012 - 10.1371/journal.pbio.1001315
PLoS biology, Vol. 10 (april 2012)  

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1 Rodriguez-Plata, Maria T
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