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Articles, 1 records found
Research literature, 1 records found
Articles 1 records found  
1.
18 p, 288.5 KB Translational research opportunities regarding homologous recombination in ovarian cancer / Romeo Marín, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pardo, J.C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Quiroga, Vanesa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Román, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Solé, Francesc (Institut Germants Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Homologous recombination (HR) is a DNA repair pathway that is deficient in 50% of high-grade serous ovarian carcinomas (HGSOC). Deficient HR (DHR) constitutes a therapeutic opportunity for these patients, thanks to poly (ADP-ribose) polymerases (PARP) inhibitors (PARPi; olaparib, niraparib, and rucaparib are already commercialized). [...]
2018 - 10.3390/ijms19103249
International Journal of Molecular Sciences, Vol. 19 Núm. 10 (19 2018) , p. 3249  

Research literature 1 records found  
1.
83 p, 952.5 KB Factors pronòstics inicials i tardans en els tumors epitelials no benignes de l'ovari : des del diagnòstic fins a les complicacions / Romeo Marín, Margarita, autor. ; Rosell Costa, R., supervisor acadèmic. ; Balañá, Carmen, supervisor acadèmic. ; Ribera Santasusana, J. M. (José María) supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Medicina.
Els tumors epitelials no benignes de l'ovari comprenen càncers i tumors borderline (BT) originats a l'ovari, trompes de Fal·lopi o peritoneu. Malgrat diferències histopatològiques i moleculars, comparteixen la via de disseminació transcelòmica, procediments diagnòstics i quirúrgics, i alguns d'ells la carcinogènesi. [...]
Non-benign epithelial ovarian tumors comprise cancers and borderline tumors (BT) that arise from the ovary, the Fallopian tubes, or the peritoneum. Despite histopathologic and molecular differences, they share a common transcelomic spreading way, diagnostic and surgical procedures and some of them are related in their carcinogenesis. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017.  

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