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9 p, 287.7 KB The Prognostic Value of BRCA1 mRNA Expression Levels Following Neoadjuvant Chemotherapy in Breast Cancer / Margeli, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cirauqui, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castella, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tapia, Gustavo (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ; Costa, Carlota (Institut Universitari Dexeus) ; Gimenez-Capitan, Ana (Institut Universitari Dexeus) ; Barnadas, Agusti (Institut d'Investigació Biomèdica Sant Pau) ; Ronco, Maria Sanchez (Universidad de Alcalá de Henares) ; Benlloch, Susana (Institut Universitari Dexeus) ; Taron, Miquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rosell, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
A fraction of sporadic breast cancers has low BRCA1 expression. BRCA1 mutation carriers are more likely to achieve a pathological complete response with DNA-damage-based chemotherapy compared to non-mutation carriers. [...]
2010 - 10.1371/journal.pone.0009499
PLoS ONE, Vol. 5 (3 2010)  

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