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16 p, 3.8 MB |
Disulfide driven folding for a conditionally disordered protein
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Fraga, Hugo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Pujols, Jordi (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Gil-Garcia, Marcos (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Bernardo-Seisdedos, Ganeko (CIC BioGUNE) ;
Santambrogio, Carlo (University of Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ;
Bech-Serra, Joan-Josep (Vall d'Hebron Institute d'Oncologia) ;
Canals, Francesc (Vall d'Hebron Institute d'Oncologia) ;
Bernadó, Pau (Centre de biochimie Structurale (Montpellier)) ;
Grandori, Rita (University of Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ;
Millet, Oscar (CIC BioGUNE) ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Conditionally disordered proteins are either ordered or disordered depending on the environmental context. The substrates of the mitochondrial intermembrane space (IMS) oxidoreductase Mia40 are synthesized on cytosolic ribosomes and diffuse as intrinsically disordered proteins to the IMS, where they fold into their functional conformations; behaving thus as conditionally disordered proteins. [...]
2017 -  10.1038/s41598-017-17259-4
Scientific reports (Nature Publishing Group), Vol. 7 (2017) , art. 16994
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14 p, 1.1 MB |
Complex evolutionary history of the mammalian histone H1.1-H1.5 gene family
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Ponte Marull, Immaculada (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Romero, Devani (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Yero Corona, Daniel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Suau León, Pere (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
H1 is involved in chromatin higher-order structure and gene regulation. H1 has a tripartite structure. The central domain is stably folded in solution, while the N- and C-terminal domains are intrinsically disordered. [...]
2017 - 10.1093/molbev/msw241
Molecular biology and evolution, Vol. 34, issue 3 (March 2017) , p. 545-558
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3.
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5 p, 1.2 MB |
Sequence conservation of linker histones between chicken and mammalian species
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Sarg, Bettina (Innsbruck Medical University. Biocenter. Division of Clinical Biochemistry) ;
López, Rita (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Lindner, Herbert (Innsbruck Medical University. Biocenter. Division of Clinical Biochemistry) ;
Ponte Marull, Immaculada (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Suau, Pedro (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The percent identity matrices of two sequence multiple alignments between linker histones from chicken and mammalian species are described. Linker histone protein sequences for chicken, mouse, rat and humans, available on public databases were used. [...]
2014 - 10.1016/j.dib.2014.10.002
Data in brief, Vol. 1 (December 2014) , p. 60-64
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4.
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14 p, 3.6 MB |
Linker histone partial phosphorylation : effects on secondary structure and chromatin condensation
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Lopez Ramos, Rita (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Sarg, Bettina (Innsbruck Medical University. Biocenter. Division of Clinical Biochemistry) ;
Lindner, Herbert (Innsbruck Medical University. Biocenter. Division of Clinical Biochemistry) ;
Bartolomé, Salvador (Universitat Autònoma de Barcelona. Laboratori de Luminescència i Espectroscòpia de Biomolècules) ;
Ponte Marull, Immaculada (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Suau León, Pere (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Linker histones are involved in chromatin higher-order structure and gene regulation. We have successfully achieved partial phosphorylation of linker histones in chicken erythrocyte soluble chromatin with CDK2, as indicated by HPCE, MALDI-TOF and Tandem MS. [...]
2015 - 10.1093/nar/gkv304
Nucleic acids research, Vol. 43, Núm. 9 (May 2015) , p. 4463-4476
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5.
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6.
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11 p, 749.2 KB |
Differential affinity of mammalian histone H1 somatic subtypes for DNA and chromatin
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Orrego, Mary (Universidad Autónoma de Barcelona. Departamento de Bioquímica y Biología Molecular) ;
Ponte Marull, Immaculada (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Buschati, Natascha (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Mora Giné, Xavier (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ;
Suau León, Pere (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Histone H1 is involved in the formation and maintenance of chromatin higher order structure. H1 has multiple isoforms; the subtypes differ in timing of expression, extent of phosphorylation and turnover rate. [...]
2007 - 10.1186/1741-7007-5-22
BMC biology, Vol. 5 (May 2007) , art. 22
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8.
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9.
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20 p, 1.8 MB |
Regulation of the Na+/K+-ATPase Ena1 expression by calcineurin/Crz1 under high pH stress : a quantitative study
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Petrezsélyová, Silvia (Institute of Molecular Genetics (Vestec, República Txeca)) ;
López-Malo, María (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Canadell i Sala, David (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Roque Córdova, Alicia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Serra Cardona, Albert (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Marqués, M. Carmen (Instituto de Biologia Molecular y Celular de Plantas (València, Espanya)) ;
Vilaprinyó, Ester (Universitat de Lleida) ;
Alves, Rui (Universitat de Lleida) ;
Yenush, Lynne (Instituto de Biologia Molecular y Celular de Plantas (València, Espanya)) ;
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Regulated expression of the Ena1 Na+-ATPase is a crucial event for adaptation to high salt and/or alkaline pH stress in the budding yeast Saccharomyces cerevisiae. ENA1 expression is under the control of diverse signaling pathways, including that mediated by the calcium-regulatable protein phosphatase calcineurin and its downstream transcription factor Crz1. [...]
2016 - 10.1371/journal.pone.0158424
PloS one, Vol. 11 Num. 6 (June 2016) , p. 1-20
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