Results overview: Found 12 records in 0.01 seconds.
Articles, 7 records found
Research literature, 5 records found
Articles 7 records found  
1.
8 p, 1.6 MB DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues / Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Cullell, Natalia (Institut d'Investigació Biomèdica Sant Pau) ; Soriano-Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ; Torres-Aguila, Nuria P. (Institut d'Investigació Biomèdica Sant Pau) ; Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; de Moura, Manuel Castro (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Spain) ; Fernández-Sanlés, Alba (Cardiovascular Epidemiology and Genetics Research Group, Hospital del Mar Medical Research Institute, Universitat Pompeu Fabra, Barcelona, Spain) ; Esteller, Manel (Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Spain) ; Elosua, Roberto (Cardiovascular Epidemiology and Genetics Research Group, Hospital del Mar Medical Research Institute, Universitat Pompeu Fabra, Barcelona, Spain) ; Jiménez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Krupinski, Jerzy (* These authors contributed equally to this work) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Background and Purpose: Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to atheromatous plaques and ischemic stroke, while no studies of DNA methylation (DNAm) patterns of MMP or TIMP have been performed to that end. [...]
2020 - 10.18632/oncotarget.27469
Oncotarget, Vol. 11 (march 2020) , p. 905-912  
2.
Association of Apolipoprotein e with Intracerebral Hemorrhage Risk by Race/Ethnicity : A Meta-analysis / Marini, S. (Massachusetts General Hospital) ; Crawford, K. (Massachusetts General Hospital) ; Morotti, A. (Fondazione Mondino IRCCS, Pavia) ; Lee, M.J. (Massachusetts General Hospital) ; Pezzini, A. (Università degli Studi di Brescia) ; Moomaw, C.J. (University of Cincinnati) ; Flaherty, M.L. (University of Cincinnati) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer Gonzalez, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Jimenez Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tarraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Slowik, A. (Jagiellonian University Medical College, Kraków) ; Jagiella, J.M. (Jagiellonian University Medical College, Kraków) ; Pera, J. (Jagiellonian University Medical College, Kraków) ; Urbanik, A. (Jagiellonian University Medical College, Kraków) ; Pichler, A. (Jagiellonian University Medical College, Kraków) ; Hansen, B.M. (Lund University) ; McCauley, J.L. (John P. Hussman Institute for Human Genomics, Miami) ; Tirschwell, D.L. (University of Washington) ; Selim, M. (Beth Israel Deaconess Medical Center, Boston) ; Brown, D.L. (University of Michigan) ; Silliman, S.L. (University of Florida College of Medicine) ; Worrall, B.B. (University of Virginia Health System) ; Meschia, J.F. (Mayo Clinic, Jacksonville, Florida) ; Kidwell, C.S. (University of Arizona) ; Testai, F.D. (University of Illinois) ; Kittner, S.J. (University of Maryland School of Medicine) ; Schmidt, H. (Medical University of Graz) ; Enzinger, C. (Medical University of Graz) ; Deary, I.J. (University of Edinburgh) ; Rannikmae, K. (University of Edinburgh) ; Samarasekera, N. (University of Edinburgh) ; Salman, R.A.S. (University of Edinburgh) ; Sudlow, C.L. (University of Edinburgh) ; Klijn, C.J.M. (UMC Utrecht Brain Center Rudolf Magnus) ; Van Nieuwenhuizen, K.M. (UMC Utrecht Brain Center Rudolf Magnus) ; Fernandez Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Norrving, B. (Lund University) ; Lindgren, A. (Lund University) ; Goldstein, J.N. (Massachusetts General Hospital) ; Viswanathan, A. (Massachusetts General Hospital) ; Greenberg, S.M. (Massachusetts General Hospital) ; Falcone, G.J. (Yale University) ; Biffi, A. (Massachusetts General Hospital) ; Langefeld, C.D. (Wake Forest University, Winston-Salem, North Carolina) ; Woo, D. (University of Cincinnati College of Medicine) ; Rosand, J. (Massachusetts General Hospital) ; Anderson, C.D. (Massachusetts General Hospital) ; Universitat Autònoma de Barcelona
Importance: Genetic studies of intracerebral hemorrhage (ICH) have focused mainly on white participants, but genetic risk may vary or could be concealed by differing nongenetic coexposures in nonwhite populations. [...]
2019 - 10.1001/jamaneurol.2018.4519
JAMA Neurology, Vol. 76 Núm. 4 (april 2019) , p. 480-491  
3.
15 p, 517.3 KB GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke / Fernández Cadenas, Israel (Hospital Vall d'Hebron. Departament de Neurologia) ; Mendióroz, Maite (Hospital Vall d'Hebron. Departament de Neurologia) ; Giralt, Dolors (Hospital Vall d'Hebron. Departament de Neurologia) ; Nafría, Cristina (Hospital Vall d'Hebron. Departament de Neurologia) ; Garcia, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Carrera, Caty (Hospital Vall d'Hebron Departament de Neurologia) ; Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mutua Terrassa) ; Domingues-Montanari, Sophie (Hospital Vall d'Hebron. Departament de Neurologia) ; Delgado, Pilar (Hospital Vall d'Hebron. Departament de Neurologia) ; Ribó, Marc (Hospital Vall d'Hebron. Departament de Neurologia) ; Castellanos, Mar (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ; Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ; Freijo, Mari Mar (Hospital de Basurto. Departamento de Neurologia) ; Jiménez-Conde, Jordi (Hospital del Mar. Departament de Neurologia) ; Rubiera, Marta (Hospital Vall d'Hebron. Departament de Neurologia) ; Alvarez Sabín, José (Hospital Vall d'Hebron. Departament de Neurologia) ; Molina, Carlos A. (Hospital Vall d'Hebron. Departament de Neurologia) ; Font, Maria Angels (Hospital de Bellvitge. Departament de Neurologia) ; Grau Olivares, Marta (Hospital Universitari Sagrat Cor. Departament de Neurologia) ; Palomeras, Ernest (Hospital de Mataró. Departament de Neurologia) ; Perez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martinez Zabaleta, Maite (Hospital Donostia. Departamento de Neurologia) ; Masjuan, Jaime (Hospital Ramon y Cajal. Departamento de Neurologia) ; Moniche, Francisco (Hospital Universitario Virgen del Rocío. Departamento de Neurologia) ; Canovas, David (Institut d'Investigació i Innovació Parc Taulí. Departament de Neurologia) ; Piñana, Carlos (Hospital Universitario Virgen de las Nieves. Departamento de Neurologia) ; Purroy, Francisco (Hospital Universitari Arnau de Vilanova. Departament de Neurologia) ; Cocho, Dolores (Hospital de Granollers. Departament de Neurologia) ; Navas, Inma (Hospital Mútua de Terrassa. Departament de Neurologia) ; Tejero, Carlos (Hospital Clínico Universitario Lozano Blesa. Departamento de Neurologia) ; Aymerich, Nuria (Hospital de Navarra. Departamento de Neurologia) ; Cullell, Natalia (Fundació Docència i Recerca Mutua Terrassa) ; Muiño, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Serena, Joaquín (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ; Rubio, Francisco (Hospital de Bellvitge. Departament de Neurologia) ; Davalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roquer González, Jaume (Hospital del Mar. Departament de Neurologia) ; Arenillas Lara, Juan Francisco (Hospital Clínico Universitario de Valladolid. Departamento de Neurologia) ; Martí Fábregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Keene, Keith (Center for Health Disparities. East Carolina University) ; Chen, Wei-Min (Department of Public Health Sciences; Center for Public Health Genomics, University of Virginia) ; Worrall, Bradford (Department of Neurology; Department of Public Health Sciences, University of Virginia) ; Sale, Michele (Center for Public Health Genomics, University of Virginia) ; Arboix, Adrià (Hospital Universitari Sagrat Cor. Departament de Neurologia) ; Krupinski, Jerzy (Hospital Mútua de Terrassa. Departament de Neurologia) ; Montaner, Joan (Hospital Vall d'Hebron. Departament de Neurologia) ; GRECOSstudy group ; Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153  
4.
9 p, 860.2 KB Interaction of Sex and Diabetes on Outcome After Ischemic Stroke / Soriano-Reixach, Maria Montserrat (Universitat Autònoma de Barcelona) ; Vivanco-Hidalgo, Rosa María (Servei de Neurologia, IMIM-Hospital del Mar) ; Ois, Angel (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez-Campello, Ana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Roquer, Jaume (Universitat Autònoma de Barcelona. Departament de Medicina)
The relationship between ischemic stroke (IS), diabetes mellitus (DM), and sex is intriguing. The aim of this study was to assess the effect modification of sex in the association between DM and short- and long-term disability and mortality in first-ever IS patients. [...]
2018 - 10.3389/fneur.2018.00250
Frontiers in Neurology, Vol. 9 (april 2018)  
5.
6 p, 403.0 KB Prevalence of cardiovascular risk factors in people with epilepsy / Vivanco-Hidalgo, Rosa Maria (Universitat Autònoma de Barcelona) ; Gómez González, Alejandra (Parc de Salut Mar. Departament de Neurologia) ; Moreira, Antia (Parc de Salut Mar. Departament de Neurologia) ; Díez, Laura (Parc de Salut Mar. Departament de Neurologia) ; Elosua, Roberto (Fundació Institut Mar d'Investigacions Mèdiques) ; Roquer González, Jaume (Universitat Autònoma de Barcelona)
Epilepsy has been associated with cardiovascular comorbidity. This study aimed to assess the potential association between cardiovascular risk factors (s), antiepileptic drugs (s), and etiology. A single-center retrospective epilepsy cohort from the decade of 2004-2013 was assessed. [...]
2017 - 10.1002/brb3.618
Brain and behavior, Vol. 7, issue 2 (Feb. 2017)  
6.
11 p, 1.1 MB Ischemic stroke patients are biologically older than their chronological age / Soriano-Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mola-Caminal, Marina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Vivanco-Hidalgo, Rosa M. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ois, Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Campello, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sayols-Baixeras, Sergi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Jiménez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Ischemic stroke is associated with aging. It is possible to predict chronological age by measuring age-related changes in DNA methylation from multiple CpG sites across the genome, known as biological age. [...]
2016 - 10.18632/aging.101028
Aging (Albany NY), Vol. 8 (august 2016) , p. 2655-2665  
7.
11 p, 168.8 KB Genetic variants in CETP increase risk of intracerebral hemorrhage / Anderson, Christopher D. (Program in Medical and Population Genetics, Broad Institute) ; Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Phuah, Chia-Ling (Program in Medical and Population Genetics, Broad Institute) ; Radmanesh, Farid (Program in Medical and Population Genetics, Broad Institute) ; Brouwers, H. Bart (Program in Medical and Population Genetics, Broad Institute) ; Battey, Thomas W. K. (Program in Medical and Population Genetics, Broad Institute) ; Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ; Peloso, Gina M. (Program in Medical and Population Genetics, Broad Institute) ; Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ; Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ; Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Selim, Magdy (Beth Israel Deaconess Medical Center) ; Meschia, James F. (Mayo Clinic) ; Brown, Devin L. (University of Michigan Health System) ; Worrall, Bradford B. (University of Virginia Health System) ; Silliman, Scott L. (University of Florida College of Medicine) ; Tirschwell, David L. (University of Washington) ; Flaherty, Matthew L. (University of Cincinnati College of Medicine) ; Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ; Schmidt, Helena (Medical University Graz) ; Hansen, Björn M. (Skåne University Hospital) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua Llanos, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ; Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ; Rannikmae, Kristiina (University of Edinburgh) ; Samarasekera, Neshika (University of Edinburgh) ; Salman, Rustam Al-Shahi (University of Edinburgh) ; Sudlow, Catherine L. (University of Edinburgh) ; Deary, Ian J. (University of Edinburgh) ; Morotti, Andrea (Neurology Clinic, University of Brescia) ; Pezzini, Alessandro (Neurology Clinic, University of Brescia) ; Pera, Joanna (Jagiellonian University Medical College) ; Urbanik, Andrzej (Jagiellonian University Medical College) ; Pichler, Alexander (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Norrving, Bo (Skåne University Hospital) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado Martínez, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lindgren, Arne (Skåne University Hospital) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Schmidt, Reinhold (Medical University of Graz) ; Kidwell, Chelsea S. (University of Arizona) ; Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ; Waddy, Salina P. (National Institutes of Health) ; Langefeld, Carl D. (Wake Forest University) ; Abecasis, Goncalo (University of Michigan School of Public Health) ; Willer, Cristen J. (University of Michigan Medical School) ; Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Rosand, Jonathan (Program in Medical and Population Genetics, Broad Institute) ; Universitat Autònoma de Barcelona. Departament de Neurologia
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of Neurology, Vol. 80 (october 2016) , p. 730-740  

Research literature 5 records found  
1.
67 p, 576.6 KB Factors de risc i risc cardiovascular en els pacients amb epilèpsia / Vivanco Hidalgo, Rosa Maria, autor. ; Roquer González, Jaume, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Medicina
L'epilèpsia s'ha associat a la malaltia cardiovascular (CV). El diagnòstic i control dels factors de risc cardiovascular (FRCV) junt amb les equacions per predir el risc es consideren l'abordatge principal en la prevenció primària CV. [...]
Epilepsy has been associated with cardiovascular (CV) comorbidity. The diagnosis and control of cardiovascular risk factors (CVRF) as well as the use of risk prediction equations are considered the standard approach in primary prevention of cardiovascular disease. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017.  
2.
118 p, 6.0 MB Influencia de los hábitos dietéticos y de la obesidad abdominal en el ictus isquémico / Rodríguez Campello, Ana, autor ; Roquer González, Jaume, supervisor acadèmic ; Goday Arnó, Albert, supervisor acadèmic ; Universitat Autònoma de Barcelona. Departament de Medicina
Objetivos: Analizar si existen diferencias dietéticas y antropométricas entre pacientes con ictus isquémico y controles de una misma población y evaluar si existen diferencias por género y subtipos de ictus. [...]
Objectives: To analyze if there are dietary and anthropometric differences between patients with ischemic stroke and controls of the same population and to evaluate if there are differences by gender and stroke subtypes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2017  
3.
136 p, 2.2 MB Evolució inicial dels ictus per arteriosclerosi carotídia. Severitat, deteriorament neurològic i recurrència / Cuadrado Godia, Elisa ; Roquer González, Jaume, dir. ; Cladellas Capdevila, Mercè ; Universitat Autònoma de Barcelona. Departament de Medicina
L'arteriosclerosi és la principal causa de mortalitat avui en dia a nivell mundial. Dintre de les seves manifestacions clíniques, aquesta tesi s'ha centrat en l'estudi dels ictus per arteriosclerosi carotídia (AC) , una causa molt freqüent d'ictus a la nostra població. [...]
Atherosclerosis is the leading cause of death worldwide. This thesis focuses on one of its clinical manifestations, the strokes due to carotid atherosclerosis (CA). This is one of the most frequent sources of stroke in our population and carries a high risk of recurrence. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
4.
109 p, 1.3 MB L'Ús d'escales clíniques en els ictus isquèmics secundaris a fibril·lació auricular / Giralt Steinhauer, Eva ; Roquer González, Jaume, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
La FA és l'arítmia cardíaca més freqüent. És conegut el seu elevat potencial de produir esdeveniments tromboembòlics, com els ictus isquèmics. Aquests ictus cardioembòlics no solament són freqüents sinó també s'associen a una elevada morbi-mortalitat. [...]
AF is the most common cardiac arrhythmia in clinical practice, and is a well-known risk factor for cardiogenic embolism. These cardioembolic strokes are frequent and associated with a substantial increased risk of morbidity and mortality. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2015  
5.
239 p, 1.0 MB Comparativa de niveles plasmáticos, implicaciones clínicas y costes entre pacientes tratados con valproico endovenoso genérico frente a pacientes tratados con valproico endovenoso innovador / Marín Casino, Mónica ; Mur Sierra, Antonio, dir. ; Roquer González, Jaume, dir. ; Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva
Con el objetivo de contener el gasto farmacéutico, una de las recomendaciones de las Administraciones Sanitarias es la utilización de fármacos genéricos. Su principal ventaja es un menor coste, debido al ahorro en investigación. [...]
In order to maximize cost savings, health care systems recommend the use of generic drugs. Its main advantage is lower cost, due to savings in research. However, small variations in bioavailability among generic drugs and brand-name drugs in epilepsy may be associated with negative effects with significant clinical changes (loss of seizure control, loss of jobs / driving license). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

See also: similar author names
5 Roquer, J.
6 Roquer, Jaume
1 Roquer, Jordi
1 Roquer, Josep
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