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1.
8 p, 788.7 KB A randomized phase III study of carfilzomib vs low-dose corticosteroids with optional cyclophosphamide in relapsed and refractory multiple myeloma (FOCUS) / Hájek, R. (University Hospital Ostrava) ; Masszi, T (St István and St László Hospital of Budapest) ; Petrucci,M.T. (Sapienza Università di Roma) ; Palumbo, A. (Università di Torino) ; Rosiñol, L. (Hospital Clínic de Barcelona) ; Nagler, A. (Chaim Sheba Medical Center (Israel)) ; Yong, K.L. (University College London Cancer Institute) ; Oriol, A. (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; Minarik, J. (University Hospital Olomouc and Medical Faculty of Palacky) ; Pour, L (University Hospital Ostrava) ; Dimopoulos, M.A. (National and Kapodistrian University of Athens) ; Maisnar, V. (Charles University Teaching Hospital, Hradec Králové) ; Rossi, D. (Amedeo Avogadro University of Eastern Piedmont) ; Kasparu, H. (Hospital Elisabethinen Linz) ; Van Droogenbroeck, J. (AZ Sint-Jan, Brugge, Belgium) ; Yehuda, D.B. (Hadassah Medical Center, Jerusalem, Israel) ; Hardan, I. (Meir Medical Center, Kfar-Saba, Israel) ; Jenner, M. (Southampton General Hospital, Hampshire, UK) ; Calbecka, M. (Nicolaus Copernicus Hospital, Toruń Poland) ; Dávid, M. (University of Pécs, Hungary) ; de la Rubia, J. (Hospital Universitario La Fe, València) ; Drach, J. (Medical University of Vienna) ; Gasztonyi, Z. (Petz Aladár Megyei Oktató Kórház, Vasvári Pál, Hungary) ; Górnik, S. (Zamojski Szpital Niepubliczny, Zamosc, Poland) ; Leleu, X. (Hopital Huriez, CHRU, Lille, France) ; Munder, M. (University Medicine Mainz, Germany) ; Offidani, M (Clinica di Ematologia Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Ancona, Italy) ; Zojer, N. (Center for Oncology, Hematology with Outpatient Department and Palliative Care, Wilhelminenspital, Vienna, Austria) ; Rajangam, K. (Onyx Pharmaceuticals, Inc.) ; Chang, Y.L. (Onyx Pharmaceuticals, Inc.) ; San-Miguel, J.F. (Clínica Universidad de Navarra-CIMA-IDISNA) ; Ludwig, H. (Wilhelminen Cancer Research Institute, Vienna, Austria)
This randomized, phase III, open-label, multicenter study compared carfilzomib monotherapy against low-dose corticosteroids and optional cyclophosphamide in relapsed and refractory multiple myeloma (RRMM). [...]
2017 - 10.1038/leu.2016.176
Leukemia, Vol. 31 (2017) , p. 107-114  
2.
6 p, 408.9 KB Prognostic impact of circulating plasma cells in patients with multiple myeloma : implications for plasma cell leukemia definition / Granell, Miquel (Institut d'Investigació Biomèdica Sant Pau) ; Calvo, Xavier (Laboratory of Cytology. Department of Pathology, GRETNHE, IMIM Hospital del Mar Research Institute) ; Garcia-Guiñón, Antoni (Department of Haematology, Hospital Universitari Arnau de Vilanova, Universitat de Lleida) ; Escoda, Lourdes (Department of Haematology, Hospital Joan XXIII, Universitat Rovira i Virgili) ; Abella, Eugènia (Department of Haematology. Hospital del Mar-IMIM, Universitat Autònoma de Barcelona) ; Martínez, Clara Mª (Institut d'Investigació Biomèdica Sant Pau) ; Teixidó, Montserrat (Department of Haematology, Hospital Universitari Arnau de Vilanova, Universitat de Lleida) ; Gimenez, Mª Teresa (Department of Haematology, Hospital Joan XXIII, Universitat Rovira i Virgili) ; Senín, Alicia (Department of Haematology. Hospital del Mar-IMIM, Universitat Autònoma de Barcelona) ; Sanz, Patricia (Institut d'Investigació Biomèdica Sant Pau) ; Campoy, Desirée (Department of Haematology, Hospital Universitari Arnau de Vilanova, Universitat de Lleida) ; Vicent, Ana (Department of Haematology, Hospital Joan XXIII, Universitat Rovira i Virgili) ; Arenillas, Leonor (Laboratory of Cytology. Department of Pathology, GRETNHE, IMIM Hospital del Mar Research Institute) ; Rosiñol, Laura (Amyloidosis and Myeloma Unit, Department of Haematology, Hospital Clínic and IDIBAPS, Universitat de Barcelona) ; Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Bladé, Joan (Amyloidosis and Myeloma Unit, Department of Haematology, Hospital Clínic and IDIBAPS, Universitat de Barcelona) ; de Larrea, Carlos Fernández (Amyloidosis and Myeloma Unit, Department of Haematology, Hospital Clínic and IDIBAPS, Universitat de Barcelona)
The presence of circulating plasma cells in patients with multiple myeloma is considered a marker for highly proliferative disease. In the study herein, the impact of circulating plasma cells assessed by cytology on survival of patients with multiple myeloma was analyzed. [...]
2017 - 10.3324/haematol.2016.158303
Haematologica, Vol. 102 (june 2017) , p. 1099-1104  

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