Resultats globals: 9 registres trobats en 0.01 segons.
Articles, 9 registres trobats
Articles 9 registres trobats  
1.
13 p, 6.0 MB Mesenchymal stem cells induce expression of cD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo / Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs,Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti- inflammatory regulation by Ado. [...]
2017 - 10.3389/fimmu.2017.01577
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-13  
2.
12 p, 3.6 MB Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction / Lluciá Valldeperas, Aida (Institut Germans Trias i Pujol) ; Soler Botija, Carolina (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol) ; Perea Gil, Isaac (Institut Germans Trias i Pujol) ; Sanchez, Benjamin (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Bragos, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Vunjak-Novakovic, Gordana (Columbia University. Biomedical Engineering and Medicine) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. [...]
2017 - 10.5966/sctm.2016-0079
Stem cells translational medicine, Vol. 6 (2017) , p. 970-981  
3.
9 p, 3.9 MB Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing / Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; Bragós, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Díaz Güemes, Idoia (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Crisóstomo, Verónica (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Sánchez Margallo, Francisco M. (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Llucià Vallperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Bogónez Franco, Francisco Carlos (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. [...]
2017 - 10.5966/sctm.2016-0063
Stem cells translational medicine, Vol. 6 (2017) , p. 647-655  
4.
15 p, 2.3 MB Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine / Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Pujal, Josep Maria (Universitat de Girona. Laboratori de processament cel·lular) ; Aran Canals, Gemma (Institut Germans Trias i Pujol) ; Sanjurjo, Lucía (Institut Germans Trias i Pujol) ; Franquesa, Marcel·la (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs, Francesc E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted extracellular vesicles (EVs) are envisaged as a promising natural source of nanoparticles to increase outcomes in organ transplantation and control inflammatory diseases. [...]
2017 - 10.7150/thno.16154
, Vol. 7 Núm. 2 (2017) , p. 270-284  
5.
13 p, 3.7 MB A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function / Perea-Gil, Isaac (Institut Germans Trias i Pujol) ; Prat-Vidal, Cristina (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Center of Regenerative Medicine in Barcelona, Barcelona, Spain) ; Llucià-Valldeperas, Aida (Institut Germans Trias i Pujol) ; Soler-Botija, Carolina (Institut Germans Trias i Pujol) ; Iborra Egea, Oriol (Institut Germans Trias i Pujol) ; Díaz-Güemes, Idoia (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Crisóstomo, Verónica (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Sánchez-Margallo, Francisco M. (Jesús Usón Minimally Invasive Surgery Centre, JUMISC, Cáceres, Spain) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Myocardial infarction (MI) remains a dreadful disease around the world, causing irreversible sequelae that shorten life expectancy and reduce quality of life despite current treatment. Here, the authors engineered a cell-enriched myocardial graft, composed of a decellularized myocardial matrix refilled with adipose tissue-derived progenitor cells (EMG-ATDPC). [...]
2016 - 10.1016/j.jacbts.2016.06.005
JACC: Basic to Translational Science, Vol. 1 (august 2016) , p. 360-372  
6.
8 p, 964.1 KB Telomere attrition in heart failure : a flow-FISH longitudinal analysis of circulating monocytes / Teubel, Iris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Elchinova, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Madrid, Spain) ; Fernández, Marco A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cross-sectional investigations report shorter telomeres in patients with heart failure (HF); however, no studies describe telomere length (TL) trajectory and its relationship with HF progression. Here we aimed to investigate telomere shortening over time and its relationship to outcomes. [...]
2018 - 10.1186/s12967-018-1412-z
Journal of Translational Medicine, Vol. 16 (february 2018)  
7.
9 p, 1.3 MB Mechanisms of action of sacubitril/valsartan on cardiac remodeling : a systems biology approach / Iborra-Egea, Oriol (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Perea-Gil, Isaac (Institut Germans Trias i Pujol) ; Prat-Vidal, Cristina (Institut Germans Trias i Pujol) ; Soler-Botija, Carolina (Institut Germans Trias i Pujol) ; Bayes-Genis, Antoni (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Sacubitril/Valsartan, proved superiority over other conventional heart failure management treatments, but its mechanisms of action remains obscure. In this study, we sought to explore the mechanistic details for Sacubitril/Valsartan in heart failure and post-myocardial infarction remodeling, using an in silico, systems biology approach. [...]
2017 - 10.1038/s41540-017-0013-4
NPJ Systems Biology and Applications, Vol. 3 (april 2017)  
8.
10 p, 723.5 KB Extracellular vesicles do not contribute to higher circulating levels of soluble 1 in idiopathic dilated cardiomyopathy / Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; de Gonzalo Calvo, David (Institut d'Investigació Biomèdica Sant Pau) ; Valero, Ana Gámez (Institut Germans Trias i Pujol) ; Gastelurrutia, Paloma (Institut Germans Trias i Pujol. ICREC) ; Revuelta López, Elena (Institut Germans Trias i Pujol. ICREC) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Llucià Valldeperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Iborra Egea, Oriol (Institut Germans Trias i Pujol. ICREC) ; Borràs, Francesc E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Llorente Cortés, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Idiopathic dilated cardiomyopathy () is a frequent cause of heart transplantation. Potentially valuable blood markers are being sought, and low-density lipoprotein receptor-related protein 1 (1) has been linked to the underlying molecular basis of the disease. [...]
2017 - 10.1111/jcmm.13211
Journal of Cellular and Molecular Medicine, Vol. 21 (may 2017) , p. 3000-3009  
9.
17 p, 2.3 MB Intracoronary Administration of Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells Improves Myocardial Perfusion But Not Left Ventricle Function, in a Translational Model of Acute Myocardial Infarction / Bobi, Joaquim (Universitat de Barcelona) ; Solanes, Núria (Universitat de Barcelona) ; Fernández-Jiménez, Rodrigo (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Galán-Arriola, Carlos (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Dantas, Ana Paula (Universitat de Barcelona) ; Fernández-Friera, Leticia (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Rigol-Monzó, Elisabet (Hospital Clínic de Barcelona) ; Agüero, Jaume (Hospital Universitari i Politècnic La Fe) ; Ramírez, José (Hospital Clínic de Barcelona) ; Roqué, Mercè (Universitat de Barcelona) ; Bayés Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Sánchez-González, Javier (Philips Healthcare, Madrid) ; García-Álvarez, Ana (Centro Nacional de Investigaciones Cardiovasculares Carlos III, CNIC) ; Sabaté, Manel (Universitat de Barcelona) ; Roura, Santiago (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Ibáñez, Borja (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Rigol, Montserrat (Universitat de Barcelona)
Autologous adipose tissue-derived mesenchymal stem cells (s) therapy is a promising strategy to improve post-myocardial infarction outcomes. In a porcine model of acute myocardial infarction, we studied the long-term effects and the mechanisms involved in allogeneic s administration on myocardial performance. [...]
2017 - 10.1161/JAHA.117.005771
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6 (may 2017)  

Vegeu també: autors amb noms similars
2 Roura, S.
15 Roura, Santiago
1 Roura, Sergi
Us interessa rebre alertes sobre nous resultats d'aquesta cerca?
Definiu una alerta personal via correu electrònic o subscribiu-vos al canal RSS.