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Articles, 2 records found
Articles 2 records found  
1.
7 p, 1.8 MB PrionW : a server to identify proteins containing glutamine/asparagine rich prion-like domains and their amyloid cores / Zambrano, Rafael (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Conchillo-Solé, Óscar (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Iglesias, Valentin (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Illa, Ricard (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Rousseau, Frederic (KU Leuven. Department for Cellular and Molecular Medicine) ; Schymkowitz, Joost (KU Leuven. Department for Cellular and Molecular Medicine) ; Sabate, Raimon (Universitat de Barcelona. Departament de Fisicoquímica) ; Daura i Ribera, Xavier (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Prions are a particular type of amyloids with the ability to self-perpetuate and propagate in vivo. Prion-like conversion underlies important biological processes but is also connected to human disease. [...]
2015 - 10.1093/nar/gkv490
Nucleic acids research, Vol. 43 (2015) , Web Server issue W331–W337  
2.
9 p, 627.3 KB What makes a protein sequence a prion ? / Sabaté, Raimon (Universitat de Barcelona. Departament de Fisicoquímica) ; Rousseau, Frederic (KU Leuven. Department for Cellular and Molecular Medicine) ; Schymkowitz, Joost (KU Leuven. Departement for Cellular and Molecular Medicine) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Typical amyloid diseases such as Alzheimer's and Parkinson's were thought to exclusively result from de novo aggregation, but recently it was shown that amyloids formed in one cell can cross-seed aggregation in other cells, following a prion-like mechanism. [...]
2015 - 10.1371/journal.pcbi.1004013
PLoS computational biology, Vol. 11, Issue 1 (Jan. 2015) , art. e1004013  

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1 Rousseau, F.
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