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10 p, 787.2 KB |
Granulocytes-Rich Thrombi in Cerebral Large Vessel Occlusion Are Associated with Increased Stiffness and Poorer Revascularization Outcomes
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Juega, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Li, Jiahui (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Palacio-Garcia, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez, Maite (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tiberi, Riccardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Piñana, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Requena, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Tornel, Álvaro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Villatoro, Noelia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rubiera del Fueyo, Marta A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muchada, Marian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Olivé-Gadea, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rizzo, Federica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernandez, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dios-Lascuevas, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernandez-Perez, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quesada, Helena (Hospital Universitari de Bellvitge) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
De La Torre, Carolina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gallur, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Camacho, Jessica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramon y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tomasello, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pagola Pérez Blanca, Jorge (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
We aim to identify a profile of intracranial thrombus resistant to recanalization by mechanical thrombectomy (MT) in acute stroke treatment. The first extracted clot of each MT was analyzed by flow cytometry obtaining the composition of the main leukocyte populations: granulocytes, monocytes, and lymphocytes. [...]
2023 -  10.1007/s13311-023-01385-1
Neurotherapeutics, Vol. 20 (may 2023) , p. 1167-1176
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8 p, 476.6 KB |
Blood Biomarker Panels for the Early Prediction of Stroke-Associated Complications
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Faura, Júlia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Reverté, Silvia (Hospital de Tortosa Verge de la Cinta) ;
García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Millán, Mónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castellanos, Mar (Instituto de Investigación Biomédica de A Coruña) ;
Lara-Rodríguez, Blanca (Hospital Universitari de Bellvitge) ;
Zaragoza, Josep (Hospital de Tortosa Verge de la Cinta) ;
Ventura, Oriol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Pérez, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
van Eendenburg, Cecile (Hospital Universitari de Girona Doctor Josep Trueta) ;
Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ;
López-Cancio, Elena (Hospital Universitario Central de Asturias) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubiera del Fueyo, Marta A. (Hospital Universitari Vall d'Hebron) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Acute decompensated heart failure (ADHF) and respiratory tract infections (RTIs) are potentially life-threatening complications in patients experiencing stroke during hospitalization. We aimed to test whether blood biomarker panels might predict these complications early after admission. [...]
2021 - 10.1161/JAHA.120.018946
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 10 (february 2021)
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20 p, 1.7 MB |
Timing of Recanalization and Functional Recovery in Acute Ischemic Stroke
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Tsivgoulis, Georgios (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Saqqur, Maher (Department of Neuroscience, Hamad General Hospital, Doha) ;
Sharma, Vijay K. (Division of Neurology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore) ;
Brunser, Alejandro (Department of Emergency Medicine, Clinica Alemana of Santiago, University of Desarrollo, Santiago) ;
Eggers, Jürgen (Department of Neurology, Sana Hospital Lubeck, Lübeck) ;
Mikulik, Robert (Medical Faculty, Masaryk University, Brno) ;
Katsanos, Aristeidis H. (Department of Neurology, University of Ioannina School of Medicine, Ioannina) ;
Sergentanis, Theodore N. (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Vadikolias, Konstantinos (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Perren, Fabienne (Geneva University Hospitals (Suïssa)) ;
Rubiera del Fueyo, Marta A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bavarsad Shahripour, Reza (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Nguyen, Huy Thang (Department of Cerebrovascular Disease, 115 The People Hospital, Ho Chi Minh) ;
Martínez-Sánchez, Patricia (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Safouris, Apostolos (Stroke Unit, Department of Neurology, Brugmann University Hospital, Brussels) ;
Heliopoulos, Ioannis (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Shuaib, Ashfaq (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Derksen, Carol (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Voumvourakis, Konstantinos (University General Hospital Attikon (Haidari, Grècia)) ;
Psaltopoulou, Theodora (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Alexandrov, Andrei V (Department of Neurology, University of Tennessee Health Science Center, Memphis, TN) ;
Alexandrov, Andrei V. (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Universitat Autònoma de Barcelona
Although onset-to-treatment time is associated with early clinical recovery in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (tPA), the effect of the timing of tPA-induced recanalization on functional outcomes remains debatable. [...]
2020 - 10.5853/jos.2019.01648
Journal of Stroke, Vol. 22 (january 2020) , p. 130-140
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15 p, 517.3 KB |
GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke
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Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Nafría, Cristina (Hospital Universitari Vall d'Hebron) ;
Garcia, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Carrera, Caty (Hospital Universitari Vall d'Hebron) ;
Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mútua Terrassa) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Castellanos, Mar (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martínez, Sergi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Freijo, Mari Mar (Hospital de Basurto (Bilbao, Biscaia)) ;
Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Rubiera, Marta (Hospital Universitari Vall d'Hebron) ;
Álvarez-Sabin, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Font, Maria Angels (Hospital Universitari de Bellvitge) ;
Grau Olivares, Marta (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Palomeras, Ernest (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez Zabaleta, Maite (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Masjuan, Jaime (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moniche, Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Piñana, Carlos (Hospital Universitario Virgen de las Nieves (Granada)) ;
Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Cocho, Dolores (Hospital General de Granollers) ;
Navas, Inma (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Tejero, Carlos (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Aymerich, Nuria (Complejo Hospitalario de Navarra) ;
Cullell, Natalia (Fundació Docència i Recerca Mútua Terrassa) ;
Muiño, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubio, Francisco (Hospital Universitari de Bellvitge) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Martí-Fàbregas, Joan (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Keene, Keith (Center for Health Disparities. East Carolina University) ;
Chen, Wei-Min (University of Virginia) ;
Worrall, Bradford (University of Virginia) ;
Sale, Michele (Center for Public Health Genomics, University of Virginia) ;
Arboix, Adrià (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron) ;
GRECOSstudy group ;
Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153
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9 p, 730.3 KB |
Safety and Efficacy of Solitaire Stent Thrombectomy
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Campbell, Bruce C.V ;
Hill, M. D ;
Rubiera del Fueyo, Marta A. ;
Menon, Bijoy K. ;
Demchuk, Andrew ;
Donnan, Geoffrey A. ;
Roy, Daniel ;
Thornton, John ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bonafe, Alain ;
Levy, Elad I. ;
Diener, Hans-Christoph ;
Hernández-Pérez, María ;
Pereira, Vitor Mendes ;
Blasco, Jordi ;
Quesada, Helena ;
Rempel, Jeremy ;
Jahan, Reza ;
Davis, Stephen M. ;
Stouch, Bruce C. ;
Mitchell, Peter J. ;
Jovin, Tudor G. ;
Saver, Jeffrey L.. ;
Goyal, Mayank ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Patient-level data were pooled from trials in which the Solitaire was the only or the predominant device used in a prespecified meta-analysis (SEER Collaboration): Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME), Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times (ESCAPE), Extending the Time for Thrombolysis in Emergency Neurological Deficits-Intra-Arterial (EXTEND-IA), and Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset (REVASCAT). [...]
2016 - 10.1161/STROKEAHA.115.012360
Stroke, Vol. 47 (february 2016) , p. 798-806
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