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1.
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14 p, 1.0 MB |
Effect of Combination Antibiotic Empirical Therapy on Mortality in Neutropenic Cancer Patients with Pseudomonas aeruginosa Pneumonia
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Albasanz-Puig, Adaia (Hospital Universitari de Bellvitge) ;
Durà-Miralles, Xavier (Hospital Universitari de Bellvitge) ;
Laporte-Amargós, Júlia (Hospital Universitari de Bellvitge) ;
Mussetti, Alberto (Hospital Universitari de Bellvitge) ;
Ruiz-Camps, Isabel (Hospital Universitari Vall d'Hebron) ;
Puerta-Alcalde, Pedro (Hospital Clínic i Provincial de Barcelona) ;
Abdala, Edson (Instituto do Câncer do Estado de São Paulo) ;
Oltolini, Chiara (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Akova, Murat (Hacettepe University School of Medicine) ;
Montejo, José Miguel (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mikulska, Malgorzata (University of Genoa (DISSAL) and Ospedale Policlinico San Martino) ;
Martín-Dávila, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Herrera, Fabián (Centro de Educación Médica e Investigaciones Clínicas (CEMIC)) ;
Gasch Blasi, Oriol (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Drgona, Lubos (Comenius University and National Cancer Institute) ;
Morales, Hugo Manuel Paz (Hospital Erasto Gaertner) ;
Brunel, Anne-Sophie (Lausanne University Hospital) ;
García, Estefanía (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Isler, Burcu (Istanbul Education and Research Hospital) ;
Kern, Winfried V. (University of Freiburg Medical Center) ;
Retamar-Gentil, Pilar (Universidad de Sevilla) ;
Aguado, José María (Instituto de Investigación Hospital "12 de Octubre" (i + 12)) ;
Montero, Milagros (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kanj, Souha S. (American University of Beirut Medical Center) ;
Sipahi, Oguz R. (Ege University) ;
Calik, Sebnem (University of Health Science Izmir Bozyaka Training and Research Hospital) ;
Márquez-Gómez, Ignacio (Hospital Regional Universitario de Málaga) ;
Marin, Jorge I. (Clínica Maraya (Pereira, Colòmbia)) ;
Gomes, Marisa Z. R. (Hospital Federal dos Servidores do Estado) ;
Hemmati, Philipp (Klinikum Ernst von Bergmann) ;
Araos, Rafael (Alemana Universidad del Desarrollo) ;
Peghin, Maddalena (University of Udine and Azienda Sanitaria Universitaria Integrata) ;
Del Pozo, Jose Luis (Clínica Universidad de Navarra) ;
Yáñez, Lucrecia (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Tilley, Robert (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Manzur, Adriana (Hospital Rawson) ;
Novo, Andres (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Pallarès, Natàlia (Hospital Universitari de Bellvitge) ;
Bergas, Alba (Hospital Universitari de Bellvitge) ;
Carratalà, Jordi (Hospital Universitari de Bellvitge) ;
Gudiol, Carlota (Hospital Universitari de Bellvitge) ;
Universitat Autònoma de Barcelona
To assess the effect of combination antibiotic empirical therapy on 30-day case-fatality rate in neutropenic cancer patients with Pseudomonas aeruginosa (PA) bacteremic pneumonia. This was a multinational, retrospective cohort study of neutropenic onco-hematological patients with PA bloodstream infection (BSI) (2006-2018). [...]
2022 -  10.3390/microorganisms10040733
Microorganisms, Vol. 10 (march 2022)
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2.
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12 p, 295.7 KB |
Pseudomonas aeruginosa Bloodstream Infections in Patients with Cancer : Differences between Patients with Hematological Malignancies and Solid Tumors
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Royo-Cebrecos, Cristina (Hospital Nostra Senyora de Meritxell (Principat d'Andorra)) ;
Laporte-Amargós, Júlia (Hospital Universitari de Bellvitge) ;
Peña, Marta (Hospital Universitari de Bellvitge) ;
Ruiz-Camps, Isabel (Hospital Universitari Vall d'Hebron) ;
Puerta-Alcalde, Pedro (Hospital Clínic i Provincial de Barcelona) ;
Abdala, Edson (Univesity of São Paulo) ;
Oltolini, Chiara (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Akova, Murat (Hacettepe University School of Medicine) ;
Montejo, Miguel (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mikulska, Malgorzata (University of Genoa (DISSAL) and Ospedale Policlinico San Martino) ;
Martín-Dávila, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Herrera, Fabian (Centro de Educación Médica e Investigaciones Clínicas) ;
Gasch Blasi, Oriol (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Drgona, Lubos (Comenius University and National Cancer Institute) ;
Morales, Hugo Manuel Paz (Hospital Erasto Gaertner) ;
Brunel, Anne-Sophie (Lausanne University Hospital) ;
García, Estefanía (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Isler, Burcu (Istanbul Education and Research Hospital) ;
Kern, Winfried V. (University of Freiburg Medical Center and Faculty of Medicine) ;
Palacios-Baena, Zaira R. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
de la Calle, Guillermo Maestro (Instituto de Investigación Hospital "12 de Octubre" (i+12)) ;
Montero, María Milagro (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kanj, Souha S. (American University of Beirut Medical Center) ;
Sipahi, Oguz R. (Ege University) ;
Calik, Sebnem (University of Health Science Izmir Bozyaka Training and Research Hospital) ;
Márquez-Gómez, Ignacio (Hospital Regional Universitario de Málaga) ;
Marin, Jorge I. (Clínica Maraya) ;
Gomes, Marisa Z. R. (Hospital Federal dos Servidores do Estado) ;
Hemmatti, Philipp (Charité University Medical School) ;
Araos, Rafael (Instituto de Ciencias e Innovación en Medicina) ;
Peghin, Maddalena (University of Udine and Azienda Sanitaria Universitaria Integrata in Udine) ;
Del Pozo, Jose Luis (Clínica Universitaria Navarra) ;
Yáñez, Lucrecia (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Tilley, Robert (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Manzur, Adriana (Hospital Rawson) ;
Novo, Andrés (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Carratalà, Jordi (Hospital Universitari de Bellvitge) ;
Gudiol, Carlota (Hospital Universitari de Bellvitge) ;
Universitat Autònoma de Barcelona
To assess the clinical features and outcomes of Pseudomonas aeruginosa bloodstream infection (PA BSI) in neutropenic patients with hematological malignancies (HM) and with solid tumors (ST), and identify the risk factors for 30-day mortality. [...]
2022 - 10.3390/pathogens11101132
Pathogens, Vol. 11 (september 2022)
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3.
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6 p, 603.3 KB |
Clinical efficacy of β-lactam/β-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum β-lactamase-producing Enterobacteriaceae in haematological patients with neutropaenia : a study protocol for a retrospective observational study (BICAR)
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Gudiol, Carlota (Instituto de Salud Carlos III) ;
Royo-Cebrecos, Cristina (Instituto de Salud Carlos III) ;
Tebé, Cristian (Institut d'Investigació Biomèdica de Bellvitge) ;
Abdala, Edson (University of São Paulo) ;
Akova, Murat (Hacettepe University School of Medicine) ;
Álvarez Marín, Rocío (Universidad de Sevilla) ;
Maestro-de la Calle, Guillermo (Hospital Universitario 12 de Octubre (Madrid)) ;
Cano, Angela (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Cervera, Carlos (University Hospital of Alberta) ;
Clemente, Wanessa T. (Universidade Federal. Hospital das Clínicas) ;
Martín-Dávila, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Freifeld, Alison (University of Nebraska Medical Center) ;
Gómez, Lucia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Gottlieb, Thomas (Concord Hospital) ;
Gurguí, Mercè (Institut d'Investigació Biomèdica Sant Pau) ;
Herrera, Fabián (Centro de Educación Médica e Investigaciones Clínicas (CEMIC)) ;
Manzur, Adriana (Hospital Rawson) ;
Maschmeyer, Georg (Academic Teaching Hospital of Charité University Medical School) ;
Meije, Yolanda (Hospital de Barcelona, SCIAS) ;
Montejo, Miguel (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Peghin, Maddalena (Santa Maria Misericordia University Hospital) ;
Rodríguez-Baño, Jesús (Instituto de Biomedicina de Sevilla) ;
Ruiz-Camps, Isabel (Hospital Universitari Vall d'Hebron) ;
Sukiennik, Teresa Cristina (Hospital Santa Casa de Misericórdia de Porto Alegre) ;
Carratalà, Jordi (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
Bloodstream infection (BSI) due to extended-spectrum β-lactamase-producing Gram-negative bacilli (ESBL-GNB) is increasing at an alarming pace worldwide. Although β-lactam/β-lactamase inhibitor (BLBLI) combinations have been suggested as an alternative to carbapenems for the treatment of BSI due to these resistant organisms in the general population, their usefulness for the treatment of BSI due to ESBL-GNB in haematological patients with neutropaenia is yet to be elucidated. [...]
2017 - 10.1136/bmjopen-2016-013268
BMJ open, Vol. 7 (january 2017)
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4.
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14 p, 502.9 KB |
Presenting features and early mortality from SARS-CoV-2 infection in cancer patients during the initial stage of the COVID-19 pandemic in Europe
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Pinato, David J. (Imperial College London. Department of Surgery & Cancer) ;
Lee, Alvin J. X. (University College London Hospitals) ;
Biello, Federica (University of Piemonte Orientale) ;
Seguí, Elia (Hospital Clínic i Provincial de Barcelona) ;
Aguilar-Company, Juan (Hospital Universitari Vall d'Hebron) ;
Carbó, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Bruna, Riccardo (University of Piemonte Orientale) ;
Bower, Mark (Chelsea & Westminster Hospital) ;
Rizzo, Gianpiero (Fondazione IRCCS Policlinico San Matteo) ;
Benafif, Sarah (University College London Hospitals) ;
Carmona, Carme (Hospital Universitari de Girona Doctor Josep Trueta) ;
Chopra, Neha (University College London Hospitals) ;
Cruz, Claudia Andrea (Hospital Clínic i Provincial de Barcelona) ;
D'avanzo, Francesca (University of Piemonte Orientale) ;
Evans, Joanne S. (Imperial College London) ;
Galazi, Myria (University College London Hospitals) ;
Garcia-Fructuoso, Isabel (Hospital Universitari de Girona Doctor Josep Trueta) ;
Pria, Alessia D. (Chelsea & Westminster Hospital) ;
Newsom-Davis, Thomas (Chelsea & Westminster Hospital) ;
Ottaviani, Diego (University College London Hospitals) ;
Patriarca, Andrea (University of Piemonte Orientale) ;
Reyes, Roxana (Hospital Clínic i Provincial de Barcelona) ;
Sharkey, Rachel (University of Piemonte Orientale) ;
Sng, Christopher C. T. (University College London Hospitals) ;
Wong, Yien Ning Sophia (University College London Hospitals) ;
Ferrante, Daniela (University of Piemonte Orientale) ;
Scotti, Lorenza (University of Piemonte Orientale) ;
Avanzi, Gian Carlo (University of Piemonte Orientale) ;
Bellan, Mattia (University of Piemonte Orientale) ;
Castello, Luigi Mario (University of Piemonte Orientale) ;
Marco-Hernández, Javier (Hospital Clínic i Provincial de Barcelona) ;
Mollà, Meritxell (Hospital Clínic i Provincial de Barcelona) ;
Pirisi, Mario (University of Piemonte Orientale) ;
Ruiz-Camps, Isabel (Hospital Universitari Vall d'Hebron) ;
Sainaghi, Pier Paolo (University of Piemonte Orientale) ;
Gaidano, Gianluca (University of Piemonte Orientale) ;
Brunet, Joan (Hospital Universitari de Girona Doctor Josep Trueta) ;
Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ;
Prat, Aleix (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gennari, Alessandra (University of Piemonte Orientale) ;
Universitat Autònoma de Barcelona
We describe the outcomes in cancer patients during the initial outbreak of the COVID-19 in Europe from the retrospective, multi-center observational OnCovid study. We identified 204 cancer patients from eight centers in the United Kingdom, Italy, and Spain aged > 18 (mean = 69) and diagnosed with COVID-19 between February 26th and April 1st, 2020. [...]
2020 - 10.3390/cancers12071841
Cancers, Vol. 12 Núm. 7 (july 2020) , p. 1-13
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5.
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17 p, 1.1 MB |
Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy : a position paper
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Los-Arcos, Ibai (Hospital Universitari Vall d'Hebron) ;
Iacoboni, Gloria (Vall d'Hebron Institut d'Oncologia) ;
Aguilar-Guisado, Manuela (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Alsina Manrique, Laia (Hospital Sant Joan de Déu (Manresa)) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fortuny Guasch, Claudia (Hospital Sant Joan de Déu (Manresa)) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Garcia-Vidal, Carolina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González Vicent, Marta (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Hernani, Rafael (Hospital Clínic Universitari (València)) ;
Kwon, Mi (Hospital General Universitario Gregorio Marañón) ;
Machado, Marina (Hospital General Universitario Gregorio Marañón) ;
Martínez Gómez, Xavier (Hospital Universitari Vall d'Hebron) ;
Ortiz-Maldonado, Valentín (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pinto Pla, Carolina (Hospital Clínic Universitari (València)) ;
Piñana, José Luis (Hospital Universitari i Politècnic La Fe (València)) ;
Pomar, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
Reguera-Ortega, Juan Luis (Hospital Universitari i Politècnic La Fe (València)) ;
Salavert, Miguel (Hospital Universitari i Politècnic La Fe (València)) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vázquez López, Lourdes (Hospital Universitario de Salamanca) ;
Barba, Pere (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ruiz Camps, Isabel (Universitat Autònoma de Barcelona. Departament de Medicina)
Chimeric antigen receptor (CAR) T-cell therapy is one of the most promising emerging treatments for B-cell malignancies. Recently, two CAR T-cell products (axicabtagene ciloleucel and tisagenlecleucel) have been approved for patients with aggressive B-cell lymphoma and acute lymphoblastic leukemia; many other CAR-T constructs are in research for both hematological and non-hematological diseases. [...]
2020 - 10.1007/s15010-020-01521-5
Infection, september 2020, p. 1-17
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6 p, 338.8 KB |
Impact of antibiotic resistance on outcomes of neutropenic cancer patients with Pseudomonas aeruginosa bacteraemia (IRONIC study) : Study protocol of a retrospective multicentre international study
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Albasanz-Puig, Adaia (Spanish Network for Research in Infectious Diseases) ;
Gudiol, Carlota (Spanish Network for Research in Infectious Diseases) ;
Parody Porras, Rocío (Institut Català d'Oncologia) ;
Tebe, Cristian (Institut d'Investigació Biomèdica de Bellvitge) ;
Akova, Murat (Infectious Diseases Department. Hacettepe University School of Medicine) ;
Araos, Rafael (Clínica Alemana Universidad del Desarrollo. Facultad de Medicina) ;
Bote, Alex (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Brunel, Anne-Sophie (Lausanne University Hospital) ;
Calik, Sebnem (Department of Infectious Diseases and Clinical Microbiology. University of Health Science Izmir Bozyaka Training and Research Hospital) ;
Drgona, Lubos (Oncohematology Department. Comenius University and National Cancer Institute) ;
García, Estefanía (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Hemmati, Philipp (Department of Haematology. Oncology and Palliative Care. Klinikum Ernst von Bergmann. Academic Teaching Hospital of Charite. University Medical School) ;
Herrera, Fabián (Infectious Diseases Section. Department of Medicine. Centro de Educación Médica e Investigaciones Clínicas) ;
Ibrahim, Karim Yaqub (Instituto Do Câncer Do Estado de São Paulo. Faculdade de Medicina da Universidade de São) ;
Isler, Burcu (Department of Infectious Diseases and Clinical Microbiology. Istanbul Education and Research Hospital) ;
Kanj, Souha (Infectious Diseases Division. American University of Beirut Medical Center) ;
Kern, Winfried (Division of Infectious Diseases. Department of Medicine II. University of Freiburg. Medical Center and Faculty of Medicine) ;
Maestro-de la Calle, Guillermo (Hospital Universitario 12 de Octubre (Madrid)) ;
Manzur, Adriana (Infectious Diseases. Hospital Rawson) ;
Marin, Jorge Iván (Critical Care and Clinical Microbiology Department. Universidad de Manizales) ;
Márquez-Gómez, Ignacio (Hospital Regional Universitario de Málaga) ;
Martín-Dávila, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Mikulska, Malgorzata (Division of Infectious Diseases. University of Genoa (DISSAL) and Ospedale Policlinico San Martino) ;
Montejo, José Miguel (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Montero, María Milagro (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Morales, Hugo Manuel Paz (Infectious Diseases Department. Hospital Erasto Gaertner) ;
Morales Fariña, Inmaculada (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Novo, Andrés (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Oltolini, Chiara (IRCCS San Raffaele Scientific Institute (Milà, Itàlia). Unit of Infectious and Tropical Diseases) ;
Peghin, Maddalena (Infectious Diseases Clinic. Department of Medicine. University of Udine and Azienda Sanitaria Universitaria Integrata) ;
Del Pozo, Jose Luis (Clínica Universidad de Navarra) ;
Puerta-Alcalde, Pedro (Hospital Clínic i Provincial de Barcelona) ;
Ruiz-Camps, Isabel (Hospital Universitari Vall d'Hebron) ;
Sipahi, Oguz Resat (Faculty of Medicine. Ege University) ;
Tilley, Robert (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Yáñez, Lucrecia (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Gomes, Marisa Z. R (Hospital Federal Servidores Do Estado. Ministerio da Saúde) ;
Carratalà, Jordi (Spanish Network for Research in Infectious Diseases) ;
Universitat Autònoma de Barcelona
Introduction Pseudomonas aeruginosa (PA) has historically been one of the major causes of severe sepsis and death among neutropenic cancer patients. There has been a recent increase of multidrug-resistant PA (MDRPA) isolates that may determine a worse prognosis, particularly in immunosuppressed patients. [...]
2019 - 10.1136/bmjopen-2018-025744
BMJ open, Vol. 9 Núm. 5 (january 2019) , p. e025744
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