Results overview: Found 3 records in 0.02 seconds.
Articles, 3 records found
Articles 3 records found  
1.
29 p, 1.4 MB Lipid Metabolism and Epigenetics Crosstalk in Prostate Cancer / Pardo, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gil, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Font, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ; Jordà, Mireia (Institut Germans Trias i Pujol)
Prostate cancer (PCa) is the most commonly diagnosed malignant neoplasm in men in the Western world. Localized low-risk PCa has an excellent prognosis thanks to effective local treatments; however, despite the incorporation of new therapeutic strategies, metastatic PCa remains incurable mainly due to disease heterogeneity and the development of resistance to therapy. [...]
2022 - 10.3390/nu14040851
Nutrients, Vol. 14 Núm. 4 (february 2022) , p. 851  
2.
17 p, 2.9 MB Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway / Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Howells, Lynne (University of Leicester. Departament of Cancer Studies) ; James, Mark I. (University of Leicester. Departament of Cancer Studies) ; Iwuji, Chinenye (University of Leicester. Departament of Cancer Studies) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Abad, Albert (Hospital Cima Sanitas (Barcelona)) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. [...]
2016 - 10.1038/srep24675
Scientific reports (Nature Publishing Group), Vol. 6 (April 2016)  
3.
20 p, 10.3 MB PKM2 subcellular localization is involved in oxaliplatin resistance acquisition in HT29 human colorectal cancer cell lines / Ginés Molina, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guardia, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Musulén, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Manzano, José Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Abad, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and also in patients. [...]
2015 - 10.1371/journal.pone.0123830
PloS one, Vol. 10, No. 5 (May 2015) , p. e0123830  

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