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9 p, 242.5 KB |
Relationship between jumping to conclusions and clinical outcomes in people at clinical high-risk for psychosis
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Catalan, Ana (Hospital de Basurto (Bilbao, Biscaia)) ;
Tognin, Stefania (South London and Maudsley NHS Foundation Trust) ;
Kempton, Matthew J. (National Institute for Health Research (NIHR)) ;
Stahl, Daniel (King's College London) ;
Salazar de Pablo, Gonzalo (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Nelson, Barnaby (University of Melbourne) ;
Pantelis, Christos (The University of Melbourne & Melbourne Health) ;
Riecher-Rössler, Anita (University of Basel) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo - UNIFESP) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile (Pôle Hospitalo Universitaire PEPIT C'JAAD) ;
Nordentoft, Merete (University of Copenhagen) ;
Ruhrmann, Stephan (University of Cologne) ;
Sachs, Gabriele (Medical University of Vienna) ;
Rutten, Bart P. F. (Maastricht University) ;
van Os, Jim (Universiteit Utrecht) ;
de Haan, Lieuwe (Amsterdam UMC) ;
van der Gaag, Mark (Parnassia Psychiatric Institute) ;
Valmaggia, Lucia R. (King's College London) ;
McGuire, Philip (Biomedical Research Centre (BRC))
Psychosis is associated with a reasoning bias, which manifests as a tendency to 'jump to conclusions'. We examined this bias in people at clinical high-risk for psychosis (CHR) and investigated its relationship with their clinical outcomes. [...]
2022 -  10.1017/S0033291720003396
Psychological Medicine, Vol. 52 (june 2022) , p. 1569-1577
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2.
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11 p, 691.7 KB |
The Relationship Between Grey Matter Volume and Clinical and Functional Outcomes in People at Clinical High Risk for Psychosis
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Tognin, Stefania ;
Richter, Anja ;
Kempton, Matthew J ;
Modinos, Gemma ;
Antoniades, Mathilde ;
Azis, Matilda ;
Allen, Paul ;
Bossong, Matthijs G ;
Perez, Jesus ;
Pantelis, Christos ;
Nelson, Barnaby ;
Amminger, Paul ;
Riecher-Rössler, Anita ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile ;
Glenthøj, Birte ;
Ruhrmann, Stephan ;
Sachs, Gabriele ;
Rutten, Bart P. F. ;
de Haan, Lieuwe ;
van der Gaag, Mark ;
Valmaggia, Lucia ;
McGuire, Philip
To examine the association between baseline alterations in grey matter volume (GMV) and clinical and functional outcomes in people at clinical high risk (CHR) for psychosis. 265 CHR individuals and 92 healthy controls were recruited as part of a prospective multi-center study. [...]
2022 - 10.1093/schizbullopen/sgac040
Schizophrenia Bulletin Open, Vol. 3 (june 2022)
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3.
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13 p, 726.7 KB |
Differential trajectories of tobacco smoking in people at ultra-high risk for psychosis : Associations with clinical outcomes
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Schirmbeck, Frederike (University of Amsterdam) ;
van der Ven, Els (Vrije Universiteit Amsterdam) ;
Boyette, Lindy-Lou (University of Amsterdam) ;
McGuire, Philip (King's College London) ;
Valmaggia, Lucia R. (King's College London) ;
Kempton, Matthew J. (King's College London) ;
van der Gaag, Mark (Vrije Universiteit Amsterdam) ;
Riecher-Rössler, Anita (University of Basel) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Nelson, Barnaby (The University of Melbourne) ;
Krebs, Marie-Odile (University of Paris) ;
Ruhrmann, Stephan (University of Cologne) ;
Sachs, Gabriele (Medical University of Vienna) ;
Rutten, Bart P. F. (Maastricht University Medical Centre) ;
Nordentoft, Merete (Copenhagen University Hospital) ;
de Haan, Lieuwe (University of Amsterdam) ;
Vermeulen, Jentien M. (University of Amsterdam)
People at ultra-high risk (UHR) for psychosis have a high prevalence of tobacco smoking, and rates are even higher among the subgroup that later develop a psychotic disorder. However, the longitudinal relationship between the course of tobacco smoking and clinical outcomes in UHR subjects is unknown. [...]
2022 - 10.3389/fpsyt.2022.869023
Frontiers in psychiatry, Vol. 13 (july 2022)
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4.
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8 p, 352.0 KB |
Impact of adverse childhood experiences on educational achievements in young people at clinical high risk of developing psychosis
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Tognin, Stefania (South London and Maudsley NHS Foundation Trust) ;
Catalan, Ana (Hospital de Basurto (Bilbao, Biscaia)) ;
Kempton, Matthew J. (National Institute for Health Research) ;
Nelson, Barnaby (The University of Melbourne) ;
McGorry, Patrick (University of Copenhagen) ;
Riecher-Rössler, Anita (University of Basel) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo - UNIFESP) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile (Service Hospitalo-Universitaire) ;
Nordentoft, Merete (University of Copenhagen) ;
Ruhrmann, Stephan (University of Cologne) ;
Sachs, Gabriele (Medical University of Vienna) ;
Rutten, Bart P. F. (Maastricht University) ;
van Os, Jim (Universiteit Utrecht) ;
de Haan, Lieuwe (Amsterdam UMC) ;
van der Gaag, Mark (Parnassia Psychiatric Institute) ;
McGuire, Philip (National Institute for Health Research) ;
Valmaggia, Lucia R. (King's College London)
Adverse childhood experiences (ACE) can affect educational attainments, but little is known about their impact on educational achievements in people at clinical high risk of psychosis (CHR). In total, 344 CHR individuals and 67 healthy controls (HC) were recruited as part of the European Community's Seventh Framework Programme-funded multicenter study the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI). [...]
2023 - 10.1192/j.eurpsy.2022.2351
European psychiatry, Vol. 66 (january 2023)
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5.
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8 p, 518.5 KB |
Verbal memory performance predicts remission and functional outcome in people at clinical high-risk for psychosis
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Hedges, Emily P. (King's College London. Department of Psychosis Studies) ;
Dickson, Hannah (King's College London. Department of Forensic and Neurodevelopmental Sciences) ;
Tognin, Stefania (King's College London. Department of Psychosis Studies) ;
Modinos, Gemma (King's College London. Department of Psychosis Studies) ;
Antoniades, Mathilde (Icahn School of Medicine. Department of Psychiatry) ;
van der Gaag, Mark (Parnassia Psychiatric Institute (Nova Zelanda). Department of Psychosis Research) ;
de Haan, Lieuwe (Arkin Amsterdam) ;
McGorry, Patrick (University of Melbourne. Centre for Youth Mental Health) ;
Pantelis, Christos (Melbourne Neuropsychiatry Centre) ;
Riecher-Rössler, Anita (University of Basel (Suïssa). Faculty of Medicine) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo (Brasil). Depto Psiquiatria) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile (University of Paris. GHU Psychiatrie et Neurosciences of Paris) ;
Nordentoft, Merete (Mental Health Center Copenhagen and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (Dinamarca)) ;
Ruhrmann, Stephan (University of Cologne (Alemanya). Department of Psychiatry and Psychotherapy) ;
Sachs, Gabriele (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ;
Rutten, Bart P. (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
van Os, Jim (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
Valmaggia, Lucia (King's College London) ;
McGuire, Philip (King's College London. Department of Psychosis Studies) ;
Kempton, Matthew J. (King's College London. Department of Psychosis Studies)
Robust deficits in cognitive functioning are present in people with psychosis and are evident in the early stages of the disorder. Impairments in verbal memory and verbal fluency are reliably seen in individuals at clinical high-risk for psychosis (CHR) compared to healthy populations. [...]
2021 - 10.1016/j.scog.2021.100222
Schizophrenia Research: Cognition, Vol. 28 (october 2021)
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6.
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9 p, 227.2 KB |
Sex differences in cognitive functioning of patients at-risk for psychosis and healthy controls : Results from the European Gene-Environment Interactions study
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Menghini-Müller, Stephanie (University of Basel, Department of Psychiatry) ;
Studerus, Erich (University of Basel. Department of Psychology) ;
Ittig, Sarah (University of Basel. Department of Psychiatry) ;
Valmaggia, Lucia (King's College London) ;
Kempton, Matthew J. (King's College London) ;
van der Gaag, Mark (Parnassia Psychiatric Institute. Department of Psychosis Research) ;
de Haan, Lieuwe (Mental Health Institute (Amsterdam)) ;
Nelson, Barnaby (University of Melbourne. Centre for Youth Mental Health) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo (UNIFESP). Departamento de Psiquiatria) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Jantac, Célia (University Paris Descartes) ;
Nordentoft, Merete (University of Copenhagen. Institute for Clinical Medicine) ;
Ruhrmann, Stephan (University of Cologne. Department of Psychiatry and Psychotherapy) ;
Sachs, Garbiele (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ;
Rutten, Bart P. (School for Mental Health and Neuroscience. Department of Psychiatry and Neuropsychology) ;
van Os, Jim (King's College London. Department of Psychosis Studies) ;
Riecher-Rössler, Anita (University of Basel, Department of Psychiatry) ;
LiNC-Lab Interdisciplinar Neurociências Clínicas
Sex differences in cognitive functioning have long been recognized in schizophrenia patients and healthy controls (HC). However, few studies have focused on patients with an at-risk mental state (ARMS) for psychosis. [...]
2020 - 10.1192/j.eurpsy.2019.10
European psychiatry, Vol. 63 (march 2020)
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7.
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11 p, 6.6 MB |
Obsessive-Compulsive Symptoms and Other Symptoms of the At-risk Mental State for Psychosis : A Network Perspective
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Ong, Hui Lin (Universiteit van Amsterdam) ;
Isvoranu, Adela-Maria (Universiteit van Amsterdam) ;
Schirmbeck, Frederike (Arkin Institute for Mental Health (Amsterdam)) ;
McGuire, Philip (King's College London. Department of Psychosis Studies) ;
Valmaggia, Lucia (King's College London) ;
Kempton, Matthew J. (King's College London) ;
van der Gaag, Mark (Vrije Universiteit Amsterdam) ;
Riecher-Rössler, Anita (Universität Basel) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Nelson, Barnaby (The University of Melbourne) ;
Amminger, G. Paul (Orygen) ;
McGorry, Patrick (The University of Melbourne) ;
Pantelis, Christos (University of Melbourne & Melbourne Health) ;
Krebs, Marie-Odile (University of Paris) ;
Nordentoft, Merete (University of Copenhagen) ;
Glenthøj, Birte (University of Copenhagen) ;
Ruhrmann, Stephan (University of Cologne) ;
Sachs, Gabriele (Department of Psychiatry and Psychotherapy, Medical University of Vienna) ;
Rutten, Bart P. F. (Maastricht University Medical Centre) ;
van Os, Jim (Universiteit Utrecht) ;
de Haan, Lieuwe (Arkin Institute for Mental Health (Amsterdam)) ;
Borsboom, Denny (Department of Psychology, Psychological Methods, University of Amsterdam)
The high prevalence of obsessive-compulsive symptoms (OCS) among subjects at Ultra-High Risk (UHR) for psychosis is well documented. However, the network structure spanning the relations between OCS and symptoms of the at risk mental state for psychosis as assessed with the Comprehensive Assessment of At Risk Mental States (CAARMS) has not yet been investigated. [...]
2021 - 10.1093/schbul/sbaa187
Schizophrenia bulletin, Vol. 47 (february 2021) , p. 1018-1028
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8.
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15 p, 1.4 MB |
Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis
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Pollak, Thomas A. (King's College London. Department of Psychosis Studies) ;
Kempton, Matthew J. (King's College London. Department of Psychosis Studies) ;
Iyegbe, Conrad (King's College London. Department of Psychosis Studies) ;
Vincent, Angela (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Irani, Sarosh R. (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Coutinho, Ester (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Menassa, David A. (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Jacobson, Leslie (John Radcliffe Hospital (Oxford, Regne Unit)) ;
de Haan, Lieuwe (University of Amsterdam. Department Early Psychosis) ;
Ruhrmann, Stephan (University of Cologne. Department of Psychiatry and Psychotherapy) ;
Sachs, Gabriele (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ;
Riecher-Rössler, Anita (University of Basel. Medical Faculty) ;
Krebs, Marie-Odile (University of Paris. Institut de Psychiatrie) ;
Amminger, Paul (University of Melbourne. Centre for Youth Mental Health) ;
Glenthøj, Birte (University of Copenhagen. Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
van Os, Jim (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
Rutten, Bart P. F. (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo. Institute for Prevention of Mental Disorders) ;
van der Gaag, Mark (VU University. Department of Clinical Psychology) ;
Yolken, Robert (Johns Hopkins School of Medicine. Department of Pediatrics) ;
Hotopf, Matthew (King's College London. Department of Psychological Medicine) ;
Valmaggia, Lucia (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Stone, James (King's College London. Department of Psychosis Studies) ;
David, Anthony S. (King's College London. Department of Psychosis Studies) ;
McGuire, Philip (King's College London. Department of Psychosis Studies)
Serum neuronal autoantibodies, such as those to the NMDA receptor (NMDAR), are detectable in a subgroup of patients with psychotic disorders. It is not known if they are present before the onset of psychosis or whether they are associated with particular clinical features or outcomes. [...]
2020 - 10.1038/s41380-020-00899-w
Molecular psychiatry, Vol. 26 (october 2020) , p. 2590-2604
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9.
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11 p, 481.9 KB |
Impact of comorbid affective disorders on longitudinal clinical outcomes in individuals at ultra-high risk for psychosis
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Schirmbeck, Frederike ;
Van der Burg, Nadine C. ;
Blankers, Matthijs ;
Vermeulen, Jentien M. ;
McGuire, Philip ;
Valmaggia, Lucia ;
Kempton, Matthew J. ;
Van der Gaag, Mark ;
Riecher-Rössler, Anita ;
Bressan, Rodrigo Affonseca ;
Barrantes-Vidal, Neus ;
Nelson, Barnaby ;
Amminger, G. Paul ;
McGorry, Patrick ;
Pantelis, Christos ;
Krebs, Marie-Odile ;
Ruhrmann, Stephan ;
Sachs, Gabriele ;
Rutten, Bart P. F. ;
Van Os, Jim ;
Nordentoft, Merete ;
Glenthøj, Birte ;
Fusar-Poli, Paolo ;
Haan, Lieuwe de ;
EU-GEI High Risk Study Group
Diagnoses of anxiety and/or depression are common in subjects at Ultra-High Risk for Psychosis (UHR) and associated with extensive functional impairment. Less is known about the impact of affective comorbidities on the prospective course of attenuated psychotic symptoms (APS). [...]
2021 - 10.1093/schbul/sbab088
Schizophrenia Bulletin, Núm. sbab088 (2021)
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