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22 p, 3.0 MB |
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
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Vidal Barba, Enric (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Sánchez-Martín, Manuel A. (Universidad de Salamanca. Departamento de Medicina) ;
Eraña, Hasier (Instituto de Salud Carlos III. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC)) ;
Lázaro, Sonia Pérez (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Pérez-Castro, Miguel A. (Basque Research and Technology Alliance. Centro de Investigación Cooperativa en Biociencias) ;
Otero García, Alicia (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Charco, Jorge M. (Instituto de Salud Carlos III. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Marín, Belén (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
López-Moreno, Rafael (Basque Research and Technology Alliance (BRTA). Centro de Investigación Cooperativa en Biociencias) ;
Díaz-Domínguez, Carlos M. (Basque Research and Technology Alliance. Centro de Investigación Cooperativa en Biociencias) ;
Geijo, Mariví (NEIKER-Basque Institute for Agricultural Research and Development) ;
Ordóñez, Montserrat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
di Bari, Michele (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Lorenzo, Nuria L. (Universidade de Santiago de Compostela) ;
Pirisinu, Laura (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
d'Agostino, Claudia (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Torres, Juan María (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Béringue, Vincent (Université Paris-Saclay. Institut National de La Recherche Agronomique) ;
Telling, Glenn (Colorado State University. Prion Research Center and the Department of Microbiology, Immunology, and Pathology) ;
Badiola Díez, Juan José (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Pumarola i Batlle, Martí (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Bolea, Rosa (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Nonno, Romolo (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Requena, Jesús R. (Universidade de Santiago de Compostela) ;
Castilla, Joaquín (IKERBASQUE. Basque Foundation for Science)
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is done for classical scrapie outbreaks. [...]
2022 -  10.1186/s40478-022-01477-7
Acta neuropathologica communications, Vol. 10 (december 2022)
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7 p, 716.5 KB |
Current professional standing of young medical oncologists in Spain : a nationwide survey by the Spanish Society of Medical Oncology + MIR section
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Martinez, Domingo Antonio Sanchez (IMIB, Virgen de La Arrixaca University Hospital. Department of Medical Oncology) ;
Quilez-Cutillas, Aliica (Department of Medical Oncology, Can Misses Hospital, Área de Salud de Ibiza y Formentera (ASEF), Ibiza, Illes Balears Spain) ;
Jimenez-Labaig, Pablo (Cruces University Hospital. Department of Medical Oncology) ;
Sesma, Andrea (Lozano Blesa University Clinical Hospital. Department of Medical Oncology) ;
Tarazona, Noelia (Instituto de Salud Carlos III, CIBERONC) ;
Pacheco-Barcia, Vilma (Torrejón University Hospital. Department of Medical Oncology) ;
Obispo, Berta (Hospital Universitario Infanta Leonor) ;
Paez, David (Institut d'Investigació Biomèdica Sant Pau) ;
Quintanar, Teresa (Hospital General Universitario de Elche) ;
Sanchez-Canovas, Manuel (Morales Meseguer University General Hospital. Department of Hematology and Medical Oncology) ;
Montes, Ana Fernandez (University Hospital Complex of Ourense (CHUO). Department of Medical Oncology) ;
Felip, Enriqueta (Vall d'Hebron Institut d'Oncologia) ;
Rodriguez-Lescure, Alvaro (Elche University General Hospital. Department of Medical Oncology) ;
Elez, Elena (Vall d'Hebron Institut d'Oncologia) ;
Universitat Autònoma de Barcelona
There is a lack of knowledge about the career paths and employment situation of young medical oncologists. The aim of our study was to evaluate the current professional standing of these professionals in Spain. [...]
2022 - 10.1007/s12094-022-02989-3
Clinical & Translational Oncology, november 2022, p. 1-7
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1 p, 663.0 KB |
Author Correction : Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
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Puig-Oliveras, Anna (Centre de Recerca en Agrigenòmica) ;
Revilla Sánchez, Manuel (Centre de Recerca en Agrigenòmica) ;
Castelló Farré, Anna (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Fernández, Ana I. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Genética Animal) ;
Folch, Josep M. (Centre de Recerca en Agrigenòmica) ;
Ballester Devis, Maria (Centre de Recerca en Agrigenòmica)
2022 - 10.1038/s41598-022-08878-7
Scientific reports (Nature Publishing Group), Vol. 12 (March 2022) , art. 4902
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12 p, 1.1 MB |
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
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Puig-Oliveras, Anna (Centre de Recerca en Agrigenòmica) ;
Revilla Sánchez, Manuel (Centre de Recerca en Agrigenòmica) ;
Castelló Farré, Anna (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Fernández, Ana I. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Genética Animal) ;
Folch, Josep M. (Centre de Recerca en Agrigenòmica) ;
Ballester Devis, Maria (Centre de Recerca en Agrigenòmica)
The aim of this work is to better understand the genetic mechanisms determining two complex traits affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. [...]
2016 - 10.1038/srep31803
Scientific reports (Nature Publishing Group), Vol. 6 (August 2016) , art. 31803
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5.
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27 p, 13.9 MB |
Unraveling the key to the resistance of canids to prion diseases
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Fernández-Borges, Natalia (CIC bioGUNE. Parque tecnológico de Bizkaia) ;
Parra, Beatriz (Laboratorio Central de Veterinaria) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Eraña, Hasier (CIC bioGUNE. Parque tecnológico de Bizkaia) ;
Sánchez-Martín, Manuel A. (Instituto de Investigación Biomédica de Salamanca) ;
de Castro, Jorge (Department of Infectology) ;
Elezgarai, Saioa R. (CIC bioGUNE. Parque tecnológico de Bizkaia) ;
Pumarola i Batlle, Martí (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Mayoral, Tomás (Laboratorio Central de Veterinaria) ;
Castilla, Joaquín (Basque Foundation for Science)
One of the characteristics of prions is their ability to infect some species but not others and prion resistant species have been of special interest because of their potential in deciphering the determinants for susceptibility. [...]
2017 - 10.1371/journal.ppat.1006716
PLoS pathogens, Vol. 13 (november 2017)
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17 p, 5.2 MB |
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
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Revilla Sánchez, Manuel (Centre de Recerca en Agrigenòmica) ;
Puig-Oliveras, Anna (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Castelló Farré, Anna (Centre de Recerca en Agrigenòmica) ;
Crespo-Piazuelo, Daniel (Centre de Recerca en Agrigenòmica) ;
Paludo, Ediane (Santa Catarina State University. Department of Animal Science) ;
Fernández, Ana I. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Genética Animal) ;
Ballester Devis, Maria (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Genètica i Millora Animal) ;
Folch, Josep M. (Centre de Recerca en Agrigenòmica)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, a genomic analysis of porcine CNVs based on next-generation sequencing data was carried out to identify CNVs segregating in an Iberian x Landrace backcross population and study their association with fatty acid composition and growth-related traits. [...]
2017 - 10.1371/journal.pone.017701
PloS one, Vol. 12, Num. 5 (May 2017) , art. e0177014
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12 p, 3.8 MB |
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
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Crespo-Piazuelo, Daniel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Estellé, Jordi (Université Paris-Saclay. Institut National de la Recherche Agronomique) ;
Revilla Sánchez, Manuel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Criado Mesas, Lourdes (Centre de Recerca en Agrigenòmica) ;
Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Ovilo, Cristina (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Mejora Genética Animal) ;
Fernández, Ana I. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento de Mejora Genética Animal) ;
Ballester Devis, Maria (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Genètica i Millora Animal) ;
Folch, Josep M. (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its physiological similarities. The aim of this study was to describe the microbiome composition, distribution and interaction along the Iberian pig intestinal tract and its role in whole-body energy homeostasis. [...]
2018 - 10.1038/s41598-018-30932-6
Scientific reports (Nature Publishing Group), Vol. 8 (august 2018)
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11 p, 1.4 MB |
Integrative approach using liver and duodenum RNA - Seq data identifies candidate genes and pathways associated with feed efficiency in pigs
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Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Ballester Devis, Maria (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Sánchez, Juan Pablo (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
González-Rodríguez, Olga (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Revilla Sánchez, Manuel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Reyer, Henry (Leibniz Institute for Farm Animal Biology. Institute of Genome Biology) ;
Wimmers, Klaus (University Rostock. Faculty of Agricultural and Environmental Sciences) ;
Torrallardona, David (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Quintanilla, Raquel (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
This study aims identifying candidate genes and pathways associated with feed efficiency (FE) in pigs. Liver and duodenum transcriptomes of 37 gilts showing high and low residual feed intake (RFI) were analysed by RNA-Seq. [...]
2018 - 10.1038/s41598-017-19072-5
Scientific reports (Nature Publishing Group), Vol. 8 (january 2018)
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12 p, 1.4 MB |
Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma
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Cubillos-Zapata, Carolina (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Martínez-García, Miguel Ángel (Hospital Universitari i Politècnic La Fe de València) ;
Díaz-García, Elena (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Jaureguizar, Ana (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Campos-Rodríguez, Francisco (Instituto de Biomedicina de Sevilla) ;
Sánchez-de-la-Torre, Manuel (Institut de Recerca Biomèdica de Lleida) ;
Nagore, Eduardo (Instituto Valenciano Oncologia) ;
Martorell-Calatayud, Antonio (Hospital de Manises (València)) ;
Blasco, Luis Hernández (Universidad Miguel Hernández de Elche) ;
Pastor, Esther (Hospital Universitario San Juan de Alicante) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montserrat, Josep María (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cabriada-Nuño, Valentín (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Cano-Pumarega, Irene (Hospital Universitario Ramón y Cajal (Madrid)) ;
Corral-Peñafiel, Jaime (Hospital San Pedro de Alcántara) ;
Arias, Eva (Hospital Universitario 12 de Octubre (Madrid)) ;
Mediano, Olga (Hospital Universitario de Guadalajara) ;
Somoza-González, María (Consorci Sanitari de Terrassa) ;
Dalmau-Arias, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Almendros, Isaac (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Farré, Ramon (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
López-Collazo, Eduardo (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Gozal, David (University of Missouri School of Medicine) ;
García-Rio, Francisco (Universidad Autónoma de Madrid) ;
Universitat Autònoma de Barcelona
Active transforming growth factor-β1 (TGF-β1), a cytokine partially regulated by hypoxia and obesity, has been related with poor prognosis in several tumors. We determine whether obstructive sleep apnea (OSA) increases serum levels of active TGF-β1 in patients with cutaneous melanoma (CM), assess their relationship with melanoma aggressiveness and analyze the factors related to TGF-β1 levels in obese and non-obese OSA patients. [...]
2020 - 10.1038/s41598-020-72481-x
Scientific reports (Nature Publishing Group), Vol. 10 (september 2020)
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5 p, 252.0 KB |
Impact of the adherence to medical treatment on the main urinary metabolic disorders in patients with kidney stones
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Manzo, Braulio Omar (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic)) ;
Cabrera, Jose David (UHospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic)) ;
Emiliani, Esteban (Fundació Puigvert) ;
Sánchez, Hector Manuel (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic)) ;
Eisner, Brian Howard (Massachusetts General Hospital (Boston)) ;
Torres, Jose Ernesto (Hospital Regional de Alta Especialidad del Bajío (Guanajuato, Mèxic)) ;
Universitat Autònoma de Barcelona
To assess the effect of the adherence to medical treatment on urinary parameters in the 24-h metabolic study of patients with kidney stones. A retrospective, longitudinal, descriptive, and observational study was carried out by reviewing the hospital electronic medical record from 2014 to 2018. [...]
2020 - 10.1016/j.ajur.2020.07.002
Asian Journal of Urology, Vol. 8 (august 2020) , p. 275-279
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