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15 p, 2.7 MB |
Biomarker Profiles Associated with COVID-19 Severity and Mortality
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Sánchez-Díez, Silvia (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Gómez-Ollés, Carlos (Hospital Universitari Vall d'Hebron) ;
Cruz, María Jesús (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
de Homdedeu, Miquel (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Espejo, David (Hospital Universitari Vall d'Hebron) ;
Ferrer Sancho, Jaume 1958- (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Roca, Oriol (Hospital Universitari Vall d'Hebron) ;
Pacheco, Andrés (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Introduction: The aim of this study was to analyze biomarkers that might predict the severity and progression of the SARS-CoV-2 infection, both in the acute phase and after recovery. Methods: Unvaccinated patients infected with the original strain of COVID-19 requiring ward (Group 1, n = 48) or ICU (Group 2, n = 41) admission were included. [...]
2023 -  10.3390/cimb45030128
Current Issues in Molecular Biology, Vol. 45, Issue 3 (March 2023) , p. 1998-2012
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14 p, 3.0 MB |
Immunopathological Mechanisms of Bird-Related Hypersensitivity Pneumonitis
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Sánchez-Díez, Silvia (Hospital Universitari Vall d'Hebron) ;
Cruz, María Jesús (Hospital Universitari Vall d'Hebron) ;
de Homdedeu, Miquel (Hospital Universitari Vall d'Hebron) ;
Ojanguren, Iñigo (Hospital Universitari Vall d'Hebron) ;
Romero-Mesones, Christian (Hospital Universitari Vall d'Hebron) ;
Sansano, Irene (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Bird-related hypersensitivity pneumonitis (BRHP) is an interstitial lung disease induced by avian proteins. The immunopathological pathways involved in the disease are still unknown. This study assesses the cellular immune response and the cytokine pattern in a mouse model of BRHP. [...]
2023 - 10.3390/ijms24032884
International journal of molecular sciences, Vol. 24 (february 2023)
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4.
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24 p, 2.1 MB |
Uso de realidad virtual en Geometría para el desarrollo de habilidades espaciales
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Moral-Sánchez, Silvia Natividad (Universidad de Málaga) ;
Sánchez-Compaña, María Teresa (Universidad de Málaga) ;
Romero Albaladejo, Isabel María (Universidad de Almería)
En el siglo xxi, surge la necesidad de un cambio en el paradigma educativo, siendo las TIC un medio vehicular que puede hacer posible esta consecución. En este artículo se exponen un conjunto de actividades sobre poliedros en 3. [...]
In the 21st century, there is a need for a change in the educational paradigm, and ICT can serve as a means to make it possible. This article presents a set of activities on polyhedra in 3rd of ESO (students aged between 14 and 16) to promote the acquisition and improvement of spatial skills. [...]
2023 - 10.5565/rev/ensciencias.5442
Enseñanza de las ciencias, Vol. 41 Núm. 1 (2023) , p. 125-147 (Innovaciones Didácticas)
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19 p, 807.7 KB |
Producción de materiales educativos para la enseñanza del mapuzugun : aproximación desde la experiencia y perspectivas de las y los educadores
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Castillo Sánchez, Silvia (University of Los Lagos) ;
Mayo González, Simona (Universidad Católica Silva Henríquez) ;
Soto Cárcamo, Jorge (Diego Portales University)
Se analiza la producción de materiales didácticos para la enseñanza del mapuzugun en contextos formales y no formales, desde la experiencia y perspectivas de enseñantes/educadores. Se realizaron entrevistas semiestructuradas, siguiendo la práctica del nütram (expresión del arte verbal mapuche), a diez educadores/as mayoritariamente mapuche. [...]
S'analitza la producció de materials didàctics per a l'ensenyament del mapuzugun en contextos formals i no formals, des de l'experiència i perspectives d'ensenyants/educadors. Es van realitzar entrevistes semiestructurades, seguint la pràctica del nütram (expressió de l'art verbal maputxe), a deu educadors majoritàriament maputxe. [...]
Our study focuses on Mapuzugun educational materials' production-analyzed from teachers/educators' experience in formal and non-formal contexts. We applied semi-structured interviews to ten educators, most of Mapuche heritage, following the practice of nütram (Mapuche verbal art). [...]
La production de matériel pour l'enseignement du mapuzugun dans des contextes formels et non formels est analysée à partir de l'expérience et des perspectives des enseignants/éducateurs. Des entretiens semi-directifs ont été menés selon la pratique du nütram (expression de l'art verbal mapuche) auprès d'une dizaine d'éducateurs, majoritairement mapuche. [...]
2022 - 10.5565/rev/jtl3.916
Bellaterra journal of teaching and learning language and literature, Vol. 15 Núm. 1 (2022) , p. e916 (Articles)
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14 p, 3.8 MB |
dIvergEnt : How IgE Axis Contributes to the Continuum of Allergic Asthma and Anti-IgE Therapies
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Palomares, Óscar (Universidad Complutense de Madrid) ;
Sánchez-Ramón, Silvia (Universidad Complutense de Madrid. Departamento de Microbiología y Parasitología) ;
Dávila, Ignacio (Instituto de Investigación Biomédica de Salamanca) ;
Prieto, Luis (Hospital Universitari Doctor Peset (València)) ;
Pérez de Llano, Luis (Hospital Universitario Lucus Augusti (Lugo)) ;
Lleonart, Marta (Novartis Farmacéutica (Espanya)) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Nieto, Antonio (Hospital Universitari i Politècnic La Fe (València)) ;
Universitat Autònoma de Barcelona
Asthma is an airway disease characterised by chronic inflammation with intermittent or permanent symptoms including wheezing, shortness of breath, chest tightness, and cough, which vary in terms of their occurrence, frequency, and intensity. [...]
2017 - 10.3390/ijms18061328
International journal of molecular sciences, Vol. 18 (june 2017)
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15 p, 4.5 MB |
Minimum Information about T Regulatory Cells : A Step toward Reproducibility and Standardization
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Fuchs, Anke (Technische Universität Dresden, Germany) ;
Gliwiński, Mateusz (Medical University of Gdańsk, Poland) ;
Grageda, Nathali (MRC Centre for Transplantation, King's College London, Guy's Hospital) ;
Spiering, Rachel (Newcastle University) ;
Abbas, Abul K. (University of California, San Francisco) ;
Appel, Silke (University of Bergen, Norway) ;
Bacchetta, Rosa (Stanford School of Medicine, United States) ;
Battaglia, Manuela (San Raffaele Hospital, Milan) ;
Berglund, David (Uppsala University, Sweden) ;
Blazar, Bruce (University of Minnesota, United States) ;
Bluestone, Jeffrey A. (University of California, San Francisco, United States) ;
Bornhäuser, Martin (Technische Universität Dresden, Germany) ;
ten Brinke, Anja (University of Amsterdam) ;
Brusko, Todd M. (University of Florida Diabetes Institute) ;
Cools, Nathalie (University Hospital Antwerp (Bèlgica)) ;
Cuturi, Maria Cristina (Université de Nantes) ;
Geissler, Edward (University Hospital Regensburg, Germany) ;
Giannoukakis, Nick (Carnegie Mellon University, Pittsburgh, United States) ;
Gołab, Karolina (The University of Chicago, United States) ;
Hafler, David A. (Yale School of Medicine, New Haven, United States) ;
van Ham, S. Marieke (University of Amsterdam) ;
Hester, Joanna (University of Oxford) ;
Hippen, Keli (University of Minnesota, United States) ;
Di Ianni, Mauro (University of Chieti-Pescara) ;
Ilic, Natasa (University of Belgrade) ;
Isaacs, John (National Institute for Health Research Newcastle Biomedical Research Centre at Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University) ;
Issa, Fadi (University of Oxford) ;
Iwaszkiewicz-Grzes, Dorota (Medical University of Gdańsk, Poland) ;
Jaeckel, Elmar (Department of Gastroenterology, Hepatology, Endocrinology, Diabetology, Transplantationsforschungszentrum, Medical School of Hannover (MHH)) ;
Joosten, Irma (Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboudumc, Netherlands) ;
Klatzmann, David (Hôpital Pitié-Salpêtrière, Paris) ;
Koenen, Hans (Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboudumc, Netherlands) ;
van Kooten, Cees (Leiden University Medical Center, Netherlands) ;
Korsgren, Olle (Gothenburg University, Sweden) ;
Kretschmer, Karsten (University Hospital and Medical Faculty Carl Gustav Carus of TU Dresden, Germany) ;
Levings, Megan (The University of British Columbia, Vancouver, Canada) ;
Marek-Trzonkowska, Natalia Maria (Medical University of Gdańsk, Poland) ;
Martinez-Llordella, Marc (King's College London) ;
Miljkovic, Djordje (University of Belgrade) ;
Mills, Kingston H. G. (Trinity College Dublin, Ireland) ;
Miranda, Joana P. (Universidade de Lisboa) ;
Piccirillo, Ciriaco A. (Research Institute of McGill University Health Centre, Montréal, Canada) ;
Putnam, Amy L. (University of California, San Francisco) ;
Ritter, Thomas (National University of Ireland) ;
Roncarolo, Maria Grazia (Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, ISCBRM, Stanford School of Medicine) ;
Sakaguchi, Shimon (Osaka University, Japan) ;
Sánchez-Ramón, Silvia (Hospital Clínico San Carlos (Madrid)) ;
Sawitzki, Birgit (Humboldt-Universität zu Berlin) ;
Sofronic-Milosavljevic, Ljiljana (University of Belgrade) ;
Sykes, Megan (University of California, San Francisco) ;
Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Waldmann, Herman (University of Oxford) ;
Witkowski, Piotr (The University of Chicago) ;
Wood, Kathryn J. (University of Oxford) ;
Gregori, Silvia (San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), San Raffaele Scientific Institute IRCCS) ;
Hilkens, Catharien M. U. (Newcastle University) ;
Lombardi, Giovanna (MRC Centre for Transplantation, King's College London, Guy's Hospital) ;
Lord, Phillip (School of Computing, Newcastle University) ;
Martinez-Caceres, Eva Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Trzonkowski, Piotr (Medical University of Gdańsk, Poland)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medicinal product varies between different laboratories, which in turn hampers precise comparisons of the results between the studies performed. [...]
2018 - 10.3389/fimmu.2017.01844
Frontiers in immunology, Vol. 8 (january 2018)
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8 p, 1.2 MB |
A rapid test for the environmental detection of pigeon antigen
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Sánchez-Díez, Silvia (Hospital Universitari Vall d'Hebron) ;
Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Álvarez-Simón, Daniel (Hospital Universitari Vall d'Hebron) ;
Montalvo Porro, Tomas (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Hoet, Peter M. (Department of Public Health and Primary Care, Centre for Environment and Health, Leuven) ;
Vanoirbeek, Jeroen A. (Department of Public Health and Primary Care, Centre for Environment and Health, Leuven) ;
Gómez-Ollés, Susana (Hospital Universitari Vall d'Hebron)
Avoidance of inhaled bird antigens is essential to prevent hypersensitivity pneumonitis disease progression. The aim of the present study was to develop a sandwich enzyme link immunoassay (ELISA) and an immunochromatographic test (ICT) and compare their ability to detect pigeon antigens in environmental samples. [...]
2021 - 10.1016/j.scitotenv.2021.147789
Science of the total environment, Vol. 788 (september 2021)
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13 p, 2.2 MB |
Monitoring EGFR -T790M mutation in serum/plasma for prediction of response to third-generation EGFR inhibitors in patients with lung cancer
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Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bosch-Barrera, J (Hospital Universitari de Girona Doctor Josep Trueta) ;
de Aguirre, Itziar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ramirez, Jose Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mesia, Carles (Institut Català d'Oncologia) ;
Carcereny, Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roa, Diana (Hospital Universitari de Girona Doctor Josep Trueta) ;
Sais, Elia (Hospital Universitari de Girona Doctor Josep Trueta) ;
García García, Yolanda (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Blanco, Remei (Consorci Sanitari de Terrassa. Departament d'Oncologia) ;
Sanchez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villacorta, Claudia Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Queralt, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Velarde, Jose María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rosell, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Osimertinib is efficacious in lung cancer patients with epidermal growth factor receptor (EGFR) mutations and acquired resistance (AR) to EGFR tyrosine kinase inhibitors due to EGFR -T790M mutation (T790M). [...]
2018 - 10.18632/oncotarget.25478
Oncotarget, Vol. 9 (june 2018) , p. 27074-27086
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1 p, 789.3 KB |
Correction : Monitoring EGFR -T790M mutation in serum/plasma for prediction of response to third-generation EGFR inhibitors in patients with lung cancer
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Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bosch-Barrera, J (Hospital Universitari de Girona Doctor Josep Trueta) ;
de Aguirre, Itziar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ramirez, Jose Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mesia, Carles (Institut Català d'Oncologia) ;
Carcereny, Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roa, Diana (Hospital Universitari de Girona Doctor Josep Trueta) ;
Sais, Elia (Hospital Universitari de Girona Doctor Josep Trueta) ;
García García, Yolanda (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Blanco, Remei (Consorci Sanitari de Terrassa. Departament d'Oncologia) ;
Sanchez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villacorta, Claudia Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Queralt, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Velarde, Jose María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rosell, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
2019 - 10.18632/oncotarget.26855
Oncotarget, Vol. 10 (april 2019) , p. 2576
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