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Articles, 2 records found
Articles 2 records found  
1.
19 p, 3.1 MB Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer's disease patients / Lennol, Matthew Paul (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Sánchez-Domínguez, Irene (Universitat de Barcelona. Institut de Neurociències) ; Cuchillo-Ibañez, Inmaculada (Instituto de Investigación Sanitaria y Biomédica de Alicante) ; Camporesi, Elena (Institute of Neuroscience and Physiology. Department of Psychiatry and Neurochemistry. the Sahlgrenska Academy at the University of Gothenburg) ; Brinkmalm, Gunnar (Institute of Neuroscience and Physiology. Department of Psychiatry and Neurochemistry. the Sahlgrenska Academy at the University of Gothenburg) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Soria, Guadalupe (Universitat de Barcelona. Laboratori de Neuroanatomia Quirúrgica. Facultat de Medicina i Ciències de la Salut) ; Aguado, Fernando (Universitat de Barcelona. Institut de Neurociències) ; Zetterberg, Henrik (Hong Kong Center for Neurodegenerative Diseases) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Sáez-Valero, Javier (Instituto de Investigación Sanitaria y Biomédica de Alicante) ; Universitat Autònoma de Barcelona
Objective: The purpose of this study was to examine the levels of cerebrospinal fluid (CSF) apolipoprotein E (apoE) species in Alzheimer's disease (AD) patients. Methods: We analyzed two CSF cohorts of AD and control individuals expressing different APOE genotypes. [...]
2022 - 10.1186/s13195-022-01108-2
Alzheimer's research & therapy, Vol. 14 Núm. 1 (december 2022) , p. 161  
2.
15 p, 3.8 MB Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease / Barranco, Neus (Universitat de Barcelona. Institut de Neurociències) ; Plá, Virginia (University of Rochester Medical Center) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Domínguez, Irene (Universitat de Barcelona) ; Fischer-Colbrie, Reiner (Innsbruck Medical University) ; Ferrer, Isidro (Institut d'Investigació Biomèdica de Bellvitge) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Aguado, Fernando (Universitat de Barcelona) ; Universitat Autònoma de Barcelona
New fluid biomarkers for Alzheimer's disease (AD) that reveal synaptic and neural network dysfunctions are needed for clinical practice and therapeutic trial design. Dense core vesicle (DCV) cargos are promising cerebrospinal fluid (CSF) indicators of synaptic failure in AD patients. [...]
2021 - 10.1186/s40035-021-00263-0
Translational Neurodegeneration, Vol. 10 (september 2021)  

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