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Articles, 3 records found
Articles 3 records found  
1.
12 p, 524.6 KB Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells / Huyveneers, Laura E. P. (University Medical Center Utrecht) ; Bruns, Anke (University Medical Center Utrecht) ; Stam, Arjen (University Medical Center Utrecht) ; Ellerbroek, Pauline (University Medical Center Utrecht) ; de Jong, Dorien (University Medical Center Utrecht) ; Nagy, Noémi A. (University Medical Center Utrecht) ; Gumbs, Stephanie B. H. (University Medical Center Utrecht) ; Tesselaar, Kiki (University Medical Center Utrecht) ; Bosman, Kobus (University Medical Center Utrecht) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hütter, Gero (DKMS CC) ; Brosens, Lodewijk A. A. (University Medical Center Utrecht) ; Kwon, Mi (Hospital General Universitario Gregorio Marañón) ; Diez Martin, Jose (Hospital General Universitario Gregorio Marañón) ; van der Meer, Jan T. M. (Amsterdam UMC) ; de Kort, Theun M. (Leiden University Medical Center) ; Sáez-Cirión, Asier (Université Paris Cité) ; Schulze zur Wiesch, Julian (UMC Hamburg-Eppendorf) ; Boelens, Jaap Jan (Memorial Sloan Kettering Cancer Center) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kuball, Jurgen (University Medical Center Utrecht) ; Wensing, Annemarie M. J. (University Medical Center Utrecht) ; Nijhuis, Monique (University Medical Center Utrecht)
Allo-HSCT with CCR5Δ32/Δ32 donor cells is the only curative HIV-1 intervention. We investigated the impact of allo-HSCT on the viral reservoir in PBMCs and post-mortem tissue in two patients. IciS-05 and IciS-11 both received a CCR5Δ32/Δ32 allo-HSCT. [...]
2022 - 10.3390/v14092069
Viruses, Vol. 14 (september 2022)  
Detailed record - Creative Commons
2.
9 p, 3.7 MB The Genome-wide Methylation Profile of CD4+ T Cells From Individuals With Human Immunodeficiency Virus (HIV) Identifies Distinct Patterns Associated With Disease Progression / Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lopez, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gómez Moruno, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Passaes, Caroline (Institut Pasteur) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Saez-Cirion, Asier (Institut Pasteur) ; Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
BACKGROUND: Human genetic variation-mostly in the human leukocyte antigen (HLA) and C-C chemokine receptor type 5 (CCR5) regions-explains 25% of the variability in progression of human immunodeficiency virus (HIV) infection. [...]
2021 - 10.1093/cid/ciaa1047
Clinical Infectious Diseases, Vol. 72 Núm. 9 (april 2021) , p. e256-e264  
Detailed record - Creative Commons
3.
12 p, 1.1 MB Extremely low viral reservoir in treated chronically HIV-1-infected individuals / Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Jiménez Valero, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Monceaux, Valérie (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Huot, Nicolas (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Leal, Lorna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; González Soler, Victoria (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; González-Cao, María (Hospital Universitari Dexeus (Barcelona, Catalunya)) ; Müller-Trutwin, Michaela (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Sáez-Cirión, Asier (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; García, Felipe (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Small viral reservoirs are found predominantly in HIV-1 controllers and individuals treated during acute/early HIV-1 infection. However, other HIV + individuals could naturally also harbour low viral reservoirs. [...]
2020 - 10.1016/j.ebiom.2020.102830
EBioMedicine, Vol. 57 (june 2020)  
Detailed record - Creative Commons

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