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16 p, 898.0 KB |
Diagnosis and treatment of Chiari malformation type 1 in children : the International Consensus Document
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Massimi, Luca (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Peretta, Paola (AOU Citta' della Salute e della Scienza di Torino) ;
Erbetta, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Solari, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Farinotti, Mariangela (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Ciaramitaro, Palma (AOU Citta' della Salute e della Scienza di Torino) ;
Saletti, Veronica (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Caldarelli, Massimo (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Canheu, Alexandre Casagrande (Universidade Estadual de Londrina) ;
Celada, Carlo ("Associazione Italiana Siringomielia e Arnold Chiari", Garino) ;
Chiapparini, Luisa (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Chieffo, Daniela (Fondazione Policlinico Universitario A Gemelli IRCCS and UCSC) ;
Cinalli, Giuseppe (Santobono-Pausilipon Children's Hospital) ;
Di Rocco, Federico (Université de Lyon) ;
Furlanetto, Marika (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giordano, Flavio (Meyer Pediatric Hospital, Florence) ;
Jallo, George (Johns Hopkins All Children's Hospital) ;
James, Syril (Necker Enfants Malades Hospital) ;
Lanteri, Paola (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Lemarchand, Christian (Conseil Scientifique APAISER S&C, Treillières, France) ;
Messing-Jünger, Martina (Asklepios Kinderklinik) ;
Parazzini, Cecilia (Children Hospital V. Buzzi) ;
Paternoster, Giovanna (Necker Enfants Malades Hospital) ;
Piatelli, Gianluca (Gaslini Children's Hospital) ;
Poca, Maria. A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prabahkar, Prab (Great Ormond Street Hospital for Children, Londres) ;
Ricci, Federica (AOU Citta' della Salute e della Scienza di Torino) ;
Righini, Andrea (Children Hospital V. Buzzi) ;
Sala, Francesco (Great Ormond Street Hospital for Children (Londres)) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Stoodley, Marcus (Macquarie University Clinical Associates) ;
Talamonti, Giuseppe (ASST Niguarda) ;
Thompson, Dominic (Great Ormond Street Hospital for Children (Londres)) ;
Triulzi, Fabio (University of Milan) ;
Zucchelli, Mino (IRCCS Istituto delle Scienze Neurologiche di Bologna) ;
Valentini, Laura (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Universitat Autònoma de Barcelona
Chiari malformation type 1 (CM1) is a rare condition where agreed classification and treatment are still missing. The goal of this study is to achieve a consensus on the diagnosis and treatment of CM1 in children. [...]
2021 -  10.1007/s10072-021-05317-9
Neurological Sciences, Vol. 43 (june 2021) , p. 1311-1326
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11 p, 753.1 KB |
Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism : A Microdialysis Study in Patients with Traumatic Brain Injuries
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Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Merino, Maria-Angels (Hospital Universitari Vall d'Hebron) ;
Sánchez-Guerrero, Angela (Hospital Universitari Vall d'Hebron) ;
Arikan, Fuat (Hospital Universitari Vall d'Hebron) ;
Vidal-Jorge, Marian (Hospital Universitari Vall d'Hebron) ;
Martínez-Valverde, Tamara (Hospital Universitari Vall d'Hebron) ;
Rey Pérez, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Riveiro, Marilyn (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca, Maria-Antonia (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traumatic brain injury (TBI) subjected to brain microdialysis monitoring to analyze the agreement between these two biomarkers and to indicate brain energy metabolism dysfunction. [...]
2014 - 10.1371/journal.pone.0102540
PloS one, Vol. 9 (july 2014)
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6 p, 916.0 KB |
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
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De Mattos-Arruda, Leticia (Universitat Autònoma de Barcelona) ;
Mayor, Regina (Vall d'Hebron Institut d'Oncologia) ;
Ng, Charlotte K. Y. (Memorial Sloan Kettering Cancer Center) ;
Weigelt, Britta (Memorial Sloan Kettering Cancer Center) ;
Martinez-Ricarte, Fran (Universitat Autònoma de Barcelona) ;
Torrejon, Davis (Vall d'Hebron Institut d'Oncologia) ;
Oliveira, Mafalda (Vall d'Hebron Institut d'Oncologia) ;
Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ;
Raventós, Carolina (Vall d'Hebron Institut d'Oncologia) ;
Tang, Jiabin (Memorial Sloan Kettering Cancer Center) ;
Guerini-Rocco, Elena (Memorial Sloan Kettering Cancer Center) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lois, Sergio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marín, Oscar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de la Cruz, Xavier (Institució Catalana de Recerca i Estudis Avançats) ;
Piscuoglio, Salvatore (Memorial Sloan Kettering Cancer Center) ;
Towers, Russel (Department of Surgery, Memorial Sloan Kettering Cancer Center) ;
Vivancos, Ana (Vall d'Hebron Institut d'Oncologia) ;
Peg, Vicente (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramón y Cajal, Santiago (Universitat Autònoma de Barcelona) ;
Carles, Joan (Vall d'Hebron Institut d'Oncologia) ;
Rodon, Jordi (Vall d'Hebron Institut d'Oncologia) ;
González-Cao, María (Quirón Dexeus University Hospital) ;
Tabernero, Josep (Universitat Autònoma de Barcelona) ;
Felip, Enriqueta (Universitat Autònoma de Barcelona) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Berger, Michael F. (Memorial Sloan Kettering Cancer Center) ;
Cortés, Javier (Universitat Autònoma de Barcelona) ;
Reis-Filho, Jorge S. (Memorial Sloan Kettering Cancer Center) ;
Seoane Suárez, Joan (Universitat Autònoma de Barcelona)
Cell-free circulating tumour DNA (ctDNA) in plasma has been shown to be informative of the genomic alterations present in tumours and has been used to monitor tumour progression and response to treatments. [...]
2015 - 10.1038/ncomms9839
Nature communications, Vol. 6 (november 2015)
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21 p, 3.3 MB |
Malignant infarction of the middle cerebral artery in a porcine model. A pilot study
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Arikan, Fuat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martínez-Valverde, Tamara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Guerrero, Ángela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Campos, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteves, Marielle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gándara, Dario F (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torné, Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castro, Lidia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dalmau Bueno, Antoni (Animal Breeding and Genetics Program (Girona)) ;
Tibau, Joan (Animal Breeding and Genetics Program, Monells (Girona)) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Interspecies variability and poor clinical translation from rodent studies indicate that large gyrencephalic animal stroke models are urgently needed. We present a proof-of-principle study describing an alternative animal model of malignant infarction of the middle cerebral artery (MCA) in the common pig and illustrate some of its potential applications. [...]
2017 - 10.1371/journal.pone.0172637
PloS one, Vol. 12 (february 2017)
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22 p, 1.6 MB |
Neurodevelopmental profile in children with benign external hydrocephalus syndrome. A pilot cohort study
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Maruccia, Federica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gomariz, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosas, Katiuska (Hospital Universitari Vall d'Hebron) ;
Durduran, Turgut (Institut de Ciències Fotòniques) ;
Paredes Carmona, Fernando (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona)
Purpose The management of children with benign external hydrocephalus (BEH) remains controversial. Most BEH children do well in the long-term, but a substantial number have temporary or permanent psychomotor delays. [...]
2021 - 10.1007/s00381-021-05201-z
Child's Nervous System, 10 May 2021
2 documents
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20 p, 3.7 MB |
Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion
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Gerzanich, Volodymyr (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Stokum, Jesse A. (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Ivanova, Svetlana (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Woo, Seung Kyoon (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Tsymbalyuk, Orest (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Sharma, Amit (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Akkentli, Fatih (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Imran, Ziyan (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Aarabi, Bizhan (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Simard, J. Marc (Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland) ;
Universitat Autònoma de Barcelona
In severe traumatic brain injury (TBI), contusions often are worsened by contusion expansion or hemorrhagic progression of contusion (HPC), which may double the original contusion volume and worsen outcome. [...]
2019 - 10.1089/neu.2018.5986
Journal of Neurotrauma, Vol. 36 (march 2019) , p. 1060-1079
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9 p, 803.7 KB |
WSES consensus conference guidelines : monitoring and management of severe adult traumatic brain injury patients with polytrauma in the first 24 hours
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Picetti, Edoardo (University Hospital of Parma) ;
Rossi, Sandra (University Hospital of Parma) ;
Abu-Zidan, Fikri M. (UAE University) ;
Ansaloni, Luca (Bufalini Hospital) ;
Armonda, Rocco (Georgetown University School of Medicine) ;
Baiocchi, Gian Luca (University of Brescia) ;
Bala, Miklosh (Hadassah Hebrew University Medical Center) ;
Balogh, Zsolt J. (University of Newcastle) ;
Berardino, Maurizio (CTO Hospital) ;
Biffl, Walter L. (Scripps Memorial Hospital) ;
Bouzat, Pierre (University Hospital of Grenoble-Alpes) ;
Buki, Andras (University of Pécs) ;
Ceresoli, Marco (University of Milan-Bicocca) ;
Chesnut, Randall M. (University of Washington) ;
Chiara, Osvaldo (University of Milano) ;
Citerio, Giuseppe (San Gerardo Hospital) ;
Coccolini, Federico (Bufalini Hospital) ;
Coimbra, Raul (Riverside University Health System Medical Center) ;
Di Saverio, Salomone (Cambridge University Hospitals NHS Foundation Trust (Regne Unit)) ;
Fraga, Gustavo P. (University of Campinas) ;
Gupta, Deepak (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Helbok, Raimund (University of Innsbruck) ;
Hutchinson, Peter J. (University of Cambridge) ;
Kirkpatrick, Andrew W. (Foothills Medical Centre) ;
Kinoshita, Takahiro (Osaka General Medical Center) ;
Kluger, Yoram (Rambam Health Campus) ;
Leppaniemi, Ari (Helsinki University Hospital (Finlàndia)) ;
Maas, Andrew I. R. (University of Antwerp) ;
Maier, Ronald V. (University of Washington School of Medicine) ;
Minardi, Francesco (University Hospital of Parma) ;
Moore, Ernest (Denver Health) ;
Myburgh, John A. (University of New South Wales) ;
Okonkwo, David O. (University of Pittsburgh Medical Center) ;
Otomo, Yasuhiro (Tokyo Medical and Dental University) ;
Rizoli, Sandro (Hamad General Hospital) ;
Rubiano, Andres M. (MEDITECH Foundation) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Sartelli, Massimo (Macerata Hospital) ;
Scalea, Thomas M. (University of Maryland School of Medicine) ;
Servadei, Franco (Humanitas University and Research Hospital) ;
Stahel, Philip F. (Rocky Vista University) ;
Stocchetti, Nino (Milan University) ;
Taccone, Fabio S. (Université Libre de Bruxelles) ;
Tonetti, Tommaso (University Hospital of Parma) ;
Velmahos, George (Massachusetts General Hospital (Boston)) ;
Weber, Dieter (Cincinnati Children's Hospital Medical Center (CCHMC). Center for Fetal and Placental Research) ;
Catena, Fausto (University Hospital of Parma) ;
Universitat Autònoma de Barcelona
The acute phase management of patients with severe traumatic brain injury (TBI) and polytrauma represents a major challenge. Guidelines for the care of these complex patients are lacking, and worldwide variability in clinical practice has been documented in recent studies. [...]
2019 - 10.1186/s13017-019-0270-1
World Journal of Emergency Surgery : WJES, Vol. 14 (november 2019)
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16 p, 748.4 KB |
The Sport Concussion Assessment Tool (SCAT2) for evaluating civilian mild traumatic brain injury. A pilot normative study
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Rădoi, Andreea (Universitat Autònoma de Barcelona) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona) ;
Gándara, Dario F. (Hospital Universitari Vall d'Hebron) ;
Castro, Lidia (Universitat Autònoma de Barcelona) ;
Cevallos, M. (Hospital Universitari Vall d'Hebron) ;
Pacios, M.E. (Hospital Universitari Vall d'Hebron) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Universitat Autònoma de Barcelona
Self-report measures, particularly symptom inventories, are critical tools for identifying patients with persistent post-concussion symptoms and their follow-up. Unlike in military or sports-related assessment, in general civilian settings pre-injury levels of concussion-like symptoms are lacking. [...]
2019 - 10.1371/journal.pone.0212541
PloS one, Vol. 14 Núm. 2 (february 2019) , p. e0212541
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