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12 p, 1.1 MB |
Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities : a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES)
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Picetti, Edoardo (University Hospital of Parma) ;
Catena, Fausto (Bufalini Hospital. Department of General and Emergency Surgery) ;
Abu-Zidan, Fikri (United Arab Emirates University. The Research Office, College of Medicine and Health Sciences) ;
Ansaloni, Luca (University of Pavia. Unit of General Surgery, San Matteo Hospital Pavia) ;
Armonda, Rocco A. (8405MedStar Washington Hospital Center. Department of Neurosurgery) ;
Bala, Miklosh (Hebrew University of Jerusalem Kiriat Hadassah. Acute Care Surgery and Trauma Unit, Department of General Surgery, Hadassah Medical Center and Faculty of Medicine) ;
Balogh, Zsolt J. (Hunter Medical Research Institute and University of Newcastle. Department of Traumatology, John Hunter Hospital) ;
Bertuccio, Alessandro (Department of Neurosurgery, SS Antonio E Biagio E Cesare Arrigo Alessandria Hospital, Alessandria, Italy) ;
Biffl, Walt L. (Scripps Clinic Medical Group) ;
Bouzat, Pierre (Université Grenoble Alpes. Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences) ;
Buki, Andras (Örebro University. Department of Neurosurgery, Faculty of Medicine and Health) ;
Cerasti, Davide (Azienda Ospedaliero-Universitaria of Parma. Neuroradiology Unit) ;
Chesnut, Randall M. (University of Washington. Department of Global Health) ;
Citerio, Giuseppe (ASST Monza. Neuroscience Department, NeuroIntensive Care Unit, Hospital San Gerardo) ;
Coccolini, Federico (Pisa University Hospital. Department of Emergency and Trauma Surgery) ;
Coimbra, Raul (Loma Linda University School of Medicine. Riverside University Health System Medical Center) ;
Coniglio, Carlo (Ospedale Maggiore Carlo Alberto Pizzardi. Department of Anesthesia, Intensive Care and Prehospital Emergency) ;
Fainardi, Enrico (University of Florence. Neuroradiology Unit, Department of Experimental and Clinical Biomedical Sciences) ;
Gupta, Deepak (All India Institute of Medical Sciences. Department of Neurosurgery, Neurosciences Centre and JPN Apex Trauma Centre) ;
Gurney, Jennifer M. (JBSA Fort Sam Houston. The Department of Defense Center of Excellence for Trauma, Joint Trauma System (JTS)) ;
Hawrylux, Gregory W. J. (Cleveland Clinic) ;
Helbok, Raimund (Medical University of Innsbruck. Neurological Intensive Care Unit, Department of Neurology) ;
Hutchinson, Peter J. A. (University of Cambridge. Department of Neurosurgery, Department of Clinical Neurosciences) ;
Iaccarino, Corrado (Azienda Ospedaliero-Universitaria di Modena. Neurosurgery Unit, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia) ;
Kolias, Angelos (University of Cambridge. Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital) ;
Maier, Ronald W. (University of Washington. Harborview Medical Center) ;
Martin, Matthew J. (Los Angeles County + USC Medical Center. Division of Trauma and Acute Care Surgery) ;
Meyfroidt, Geert (Katholieke Universiteit Leuven. Laboratory of Intensive Care Medicine) ;
Okonkwo, David O. (University of Pittsburgh Medical Center. Department of Neurological Surgery) ;
Rasulo, Frank (Spedali Civili University Hospital. Department of Anesthesia, Critical Care and Emergency) ;
Rizoli, Sandro (Hamad General Hospital (HGH). Surgery Department, Section of Trauma Surgery) ;
Rubiano, Andres (Universidad El Bosque. INUB-MEDITECH Research Group, Institute of Neurosciences) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Sams, Valerie G. (University of Cincinnati Medical Center. Trauma Critical Care and Acute Care Surgery, Air Force Center for Sustainment of Trauma and Readiness Skills) ;
Servadei, Franco (IRCCS Humanitas Research Hospital. Department of Neurosurgery) ;
Sharma, Deepak (University of Washington. Department of Anesthesiology and Pain Medicine and Neurological Surgery) ;
Shutter, Lori (UPMC/University of Pittsburgh School of Medicine. Department of Critical Care Medicine) ;
Stahel, Philip F. (Rocky Vista University. College of Osteopathic Medicine) ;
Taccone, Fabio S. (Hôpital Universitaire de Bruxelles. Department of Intensive Care) ;
Udy, Andrew (The Alfred. Department of Intensive Care and Hyperbaric Medicine) ;
Zoerle, Tommaso (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. Department of Anesthesia, Critical Care and Emergency) ;
Agnoletti, Vanni (M. Bufalini Hospital. Anesthesia and Intensive Care Unit, AUSL Romagna) ;
Bravi, Francesca (Santa Maria Delle Croci Hospital. Healthcare Administration) ;
De Simone, Belinda (Centre Hospitalier Intercommunal De Poissy/St Germain en Laye. Department of General, Digestive and Metabolic Minimally Invasive Surgery) ;
Kluger, Yoram (Rambam Health Care Campus. Department of General Surgery) ;
Martino, Costanza (Department of Anesthesiology and Acute Care, Umberto I Hospital of Lugo, Ausl Della Romagna, Lugo, Italy) ;
Moore, Ernest E. (University of Colorado. Ernest E Moore Shock Trauma Center at Denver Health) ;
Sartelli, Massimo (Department of Surgery, Macerata Hospital, Macerata, Italy) ;
Weber, Dieter (The University of Western Australia. Department of General Surgery, Royal Perth Hospital) ;
Robba, Chiara (University of Genoa. Department of Surgical Sciences and Integrated Sciences) ;
Universitat Autònoma de Barcelona
Severe traumatic brain-injured (TBI) patients should be primarily admitted to a hub trauma center (hospital with neurosurgical capabilities) to allow immediate delivery of appropriate care in a specialized environment. [...]
2023 -  10.1186/s13017-022-00468-2
World Journal of Emergency Surgery : WJES, Vol. 18 (january 2023)
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2 p, 557.4 KB |
Correction : Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES)
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Picetti, Edoardo (University Hospital of Parma) ;
Catena, Fausto (Bufalini Hospital) ;
Abu-Zidan, Fikri (United Arab Emirates University) ;
Ansaloni, Luca (University of Pavia) ;
Armonda, Rocco A. (8405MedStar Washington Hospital Center) ;
Bala, Miklosh (Hebrew University of Jerusalem Kiriat Hadassahe) ;
Balogh, Zsolt J. (Hunter Medical Research Institute and University of Newcastle) ;
Bertuccio, Alessandro (SS Antonio E Biagio E Cesare Arrigo Alessandria Hospital) ;
Biffl, Walt L. (Scripps Clinic Medical Group) ;
Bouzat, Pierre (Université Grenoble Alpes) ;
Buki, Andras (Örebro University) ;
Cerasti, Davide (Azienda Ospedaliero-Universitaria of Parma) ;
Chesnut, Randall M. (University of Washington) ;
Citerio, Giuseppe (ASST Monza) ;
Coccolini, Federico (Pisa University Hospital) ;
Coimbra, Raul (Loma Linda University School of Medicine) ;
Coniglio, Carlo (Ospedale Maggiore Carlo Alberto Pizzardi) ;
Fainardi, Enrico (University of Florence) ;
Gupta, Deepak (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Gurney, Jennifer M. (JBSA Fort Sam Houston) ;
Hawryluk, Gregory W. J. (Cleveland Clinic) ;
Helbok, Raimund (Medical University of Innsbruck) ;
Hutchinson, Peter J. A. (University of Cambridge) ;
Iaccarino, Corrado (Azienda Ospedaliero-Universitaria di Modena) ;
Kolias, Angelos (University of Cambridge) ;
Maier, Ronald W. (University of Washington) ;
Martin, Matthew J. (Los Angeles County + USC Medical Center) ;
Meyfroidt, Geert (Katholieke Universiteit Leuven) ;
Okonkwo, David O. (University of Pittsburgh Medical Center) ;
Rasulo, Frank (Spedali Civili University Hospital) ;
Rizoli, Sandro (Hamad General Hospital) ;
Rubiano, Andres (Universidad El Bosque) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Sams, Valerie G. (University of Cincinnati Medical Center) ;
Servadei, Franco (Humanitas Research Hospital (Itàlia)) ;
Sharma, Deepak (University of Washington) ;
Shutter, Lori (UPMC/University of Pittsburgh School of Medicine) ;
Stahel, Philip F. (Rocky Vista University) ;
Taccone, Fabio S. (Hôpital Universitaire de Bruxelles) ;
Udy, Andrew (The Alfred) ;
Zoerle, Tommaso (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Agnoletti, Vanni (M. Bufalini Hospital) ;
Bravi, Francesca (Santa Maria Delle Croci Hospital) ;
De Simone, Belinda (Centre Hospitalier Intercommunal De Poissy/St Germain en Laye) ;
Kluger, Yoram (Rambam Health Care Campus) ;
Martino, Costanza (Umberto I Hospital of Lugo) ;
Moore, Ernest E. (University of Colorado) ;
Sartelli, Massimo (Macerata Hospital) ;
Weber, Dieter (The University of Western Australia) ;
Robba, Chiara (University of Genoa) ;
Universitat Autònoma de Barcelona
Severe traumatic brain-injured (TBI) patients should be primarily admitted to a hub trauma center (hospital with neurosurgical capabilities) to allow immediate delivery of appropriate care in a specialized environment. [...]
2023 - 10.1186/s13017-023-00489-5
World Journal of Emergency Surgery : WJES, Vol. 18 (april 2023)
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21 p, 1.1 MB |
Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus : a proof-of-concept study
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Maruccia, Federica (ICFO-Insitut de Ciències Fotòniques) ;
Tagliabue, Susanna (ICFO-Insitut de Ciències Fotòniques) ;
Fischer, Jonas B. (HemoPhotonics) ;
Kacprzak, Michał (Nalecz Institute of Biocybernetics and Biomedical Engineering) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosas, Katiuska (Hospital Universitari Vall d'Hebron) ;
Álvarez, Ignacio Delgado (Hospital Universitari Vall d'Hebron) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Durduran, Turgut (Institució Catalana de Recerca i Estudis Avançats) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona)
Benign external hydrocephalus (BEH) is considered a self-limiting pathology with a good prognosis. However, some children present a pathological intracranial pressure (ICP) characterized by quantitative and qualitative alterations (the so-called B-waves) that can lead to neurological sequelae. [...]
2022 - 10.1117/1.NPh.9.4.045005
Neurophotonics, Vol. 9 (november 2022)
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16 p, 898.0 KB |
Diagnosis and treatment of Chiari malformation type 1 in children : the International Consensus Document
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Massimi, Luca (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Peretta, Paola (AOU Citta' della Salute e della Scienza di Torino) ;
Erbetta, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Solari, Alessandra (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Farinotti, Mariangela (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Ciaramitaro, Palma (AOU Citta' della Salute e della Scienza di Torino) ;
Saletti, Veronica (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Caldarelli, Massimo (Fondazione Policlinico Universitario A. Gemelli IRCCS) ;
Canheu, Alexandre Casagrande (Universidade Estadual de Londrina) ;
Celada, Carlo ("Associazione Italiana Siringomielia e Arnold Chiari", Garino) ;
Chiapparini, Luisa (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Chieffo, Daniela (Fondazione Policlinico Universitario A Gemelli IRCCS and UCSC) ;
Cinalli, Giuseppe (Santobono-Pausilipon Children's Hospital) ;
Di Rocco, Federico (Université de Lyon) ;
Furlanetto, Marika (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giordano, Flavio (Meyer Pediatric Hospital, Florence) ;
Jallo, George (Johns Hopkins All Children's Hospital) ;
James, Syril (Necker Enfants Malades Hospital) ;
Lanteri, Paola (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Lemarchand, Christian (Conseil Scientifique APAISER S&C, Treillières, France) ;
Messing-Jünger, Martina (Asklepios Kinderklinik) ;
Parazzini, Cecilia (Children Hospital V. Buzzi) ;
Paternoster, Giovanna (Necker Enfants Malades Hospital) ;
Piatelli, Gianluca (Gaslini Children's Hospital) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prabahkar, Prab (Great Ormond Street Hospital for Children (Londres)) ;
Ricci, Federica (AOU Citta' della Salute e della Scienza di Torino) ;
Righini, Andrea (Children Hospital V. Buzzi) ;
Sala, Francesco (Great Ormond Street Hospital for Children (Londres)) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Stoodley, Marcus (Macquarie University Clinical Associates) ;
Talamonti, Giuseppe (ASST Niguarda) ;
Thompson, Dominic (Great Ormond Street Hospital for Children (Londres)) ;
Triulzi, Fabio (University of Milan) ;
Zucchelli, Mino (IRCCS Istituto delle Scienze Neurologiche di Bologna) ;
Valentini, Laura (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Universitat Autònoma de Barcelona
Chiari malformation type 1 (CM1) is a rare condition where agreed classification and treatment are still missing. The goal of this study is to achieve a consensus on the diagnosis and treatment of CM1 in children. [...]
2021 - 10.1007/s10072-021-05317-9
Neurological Sciences, Vol. 43 (june 2021) , p. 1311-1326
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10 p, 4.1 MB |
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
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Rubio-Perez, Carlota (Vall d'Hebron Institut d'Oncologia) ;
Planas-Rigol, Ester (Vall d'Hebron Institut d'Oncologia) ;
Trincado, Juan L. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bonfill-Teixidor, Ester (Vall d'Hebron Institut d'Oncologia) ;
Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ;
Marchese, Domenica (Centre de Regulació Genòmica) ;
Moutinho, Catia (Centre de Regulació Genòmica) ;
Serna, Garazi (Vall d'Hebron Institut d'Oncologia) ;
Pedrosa, Leire (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Iurlaro, Raffaella (Vall d'Hebron Institut d'Oncologia) ;
Martinez-Ricarte, Fran (Universitat Autònoma de Barcelona) ;
Escudero, Laura (Vall d'Hebron Institut d'Oncologia) ;
Cordero Asanza, Esteban (Universitat Autònoma de Barcelona) ;
Cicuendez, Marta (Universitat Autònoma de Barcelona) ;
Ruiz, Sara (Centre de Regulació Genòmica) ;
Parra, Genís (Centre de Regulació Genòmica) ;
Nuciforo, Paolo (Vall d'Hebron Institut d'Oncologia) ;
Gonzalez, Josep (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pineda, Estela (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Tabernero, Josep (Centro de Investigación Biomédica en Red de Cáncer) ;
Heyn, Holger (Universitat Pompeu Fabra) ;
Seoane Suárez, Joan (Institució Catalana de Recerca i Estudis Avançats)
Brain metastases are the most common tumor of the brain with a dismal prognosis. A fraction of patients with brain metastasis benefit from treatment with immune checkpoint inhibitors (ICI) and the degree and phenotype of the immune cell infiltration has been used to predict response to ICI. [...]
2021 - 10.1038/s41467-021-21789-x
Nature communications, Vol. 12 (march 2021)
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11 p, 753.1 KB |
Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism : A Microdialysis Study in Patients with Traumatic Brain Injuries
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Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ;
Merino, Maria-Angels (Hospital Universitari Vall d'Hebron) ;
Sánchez-Guerrero, Angela (Hospital Universitari Vall d'Hebron) ;
Arikan Abelló, Fuat (Hospital Universitari Vall d'Hebron) ;
Vidal-Jorge, Marian (Hospital Universitari Vall d'Hebron) ;
Martínez-Valverde, Tamara (Hospital Universitari Vall d'Hebron) ;
Rey Pérez, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Riveiro, Marilyn (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traumatic brain injury (TBI) subjected to brain microdialysis monitoring to analyze the agreement between these two biomarkers and to indicate brain energy metabolism dysfunction. [...]
2014 - 10.1371/journal.pone.0102540
PloS one, Vol. 9 (july 2014)
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6 p, 916.0 KB |
Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma
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De Mattos-Arruda, Leticia (Universitat Autònoma de Barcelona) ;
Mayor, Regina (Vall d'Hebron Institut d'Oncologia) ;
Ng, Charlotte K. Y. (Memorial Sloan Kettering Cancer Center) ;
Weigelt, Britta (Memorial Sloan Kettering Cancer Center) ;
Martinez-Ricarte, Fran (Universitat Autònoma de Barcelona) ;
Torrejon, Davis (Vall d'Hebron Institut d'Oncologia) ;
Oliveira, Mafalda (Vall d'Hebron Institut d'Oncologia) ;
Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ;
Raventós, Carolina (Vall d'Hebron Institut d'Oncologia) ;
Tang, Jiabin (Memorial Sloan Kettering Cancer Center) ;
Guerini-Rocco, Elena (Memorial Sloan Kettering Cancer Center) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lois, Sergio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marín, Oscar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de la Cruz, Xavier (Institució Catalana de Recerca i Estudis Avançats) ;
Piscuoglio, Salvatore (Memorial Sloan Kettering Cancer Center) ;
Towers, Russel (Department of Surgery, Memorial Sloan Kettering Cancer Center) ;
Vivancos, Ana (Vall d'Hebron Institut d'Oncologia) ;
Peg, Vicente (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramón y Cajal, Santiago (Universitat Autònoma de Barcelona) ;
Carles, Joan (Vall d'Hebron Institut d'Oncologia) ;
Rodon, Jordi (Vall d'Hebron Institut d'Oncologia) ;
González-Cao, María (Quirón Dexeus University Hospital) ;
Tabernero, Josep (Universitat Autònoma de Barcelona) ;
Felip, Enriqueta (Universitat Autònoma de Barcelona) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Berger, Michael F. (Memorial Sloan Kettering Cancer Center) ;
Cortés, Javier (Universitat Autònoma de Barcelona) ;
Reis-Filho, Jorge S. (Memorial Sloan Kettering Cancer Center) ;
Seoane Suárez, Joan (Universitat Autònoma de Barcelona)
Cell-free circulating tumour DNA (ctDNA) in plasma has been shown to be informative of the genomic alterations present in tumours and has been used to monitor tumour progression and response to treatments. [...]
2015 - 10.1038/ncomms9839
Nature communications, Vol. 6 (november 2015)
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21 p, 3.3 MB |
Malignant infarction of the middle cerebral artery in a porcine model. A pilot study
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Arikan Abelló, Fuat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martínez-Valverde, Tamara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Guerrero, Ángela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Campos Martorell, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteves, Marielle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gándara, Dario F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torné, Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castro, Lidia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dalmau Bueno, Antoni (Animal Breeding and Genetics Program (Girona)) ;
Tibau, Joan (Animal Breeding and Genetics Program, Monells (Girona)) ;
Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Interspecies variability and poor clinical translation from rodent studies indicate that large gyrencephalic animal stroke models are urgently needed. We present a proof-of-principle study describing an alternative animal model of malignant infarction of the middle cerebral artery (MCA) in the common pig and illustrate some of its potential applications. [...]
2017 - 10.1371/journal.pone.0172637
PloS one, Vol. 12 (february 2017)
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10.
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11 p, 2.2 MB |
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
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Escudero, Laura (Vall d'Hebron Institut d'Oncologia) ;
Llort, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ;
Diaz-Navarro, Ander (Centro de Investigación Biomédica en Red de Cáncer) ;
Martinez-Ricarte, Fran (Universitat Autònoma de Barcelona) ;
Rubio-Perez, Carlota (Vall d'Hebron Institut d'Oncologia) ;
Mayor, Regina (Vall d'Hebron Institut d'Oncologia) ;
Caratù, Ginevra (Vall d'Hebron Institut d'Oncologia) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vázquez-Méndez, Élida (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lesende-Rodríguez, Iván (Universidade da Coruña) ;
Hladun, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gros, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Pastor, María Antonia (Universitat Autònoma de Barcelona) ;
Puente, Xose S. (Centro de Investigación Biomédica en Red de Cáncer) ;
Sahuquillo Barris, Juan (Universitat Autònoma de Barcelona) ;
Gallego, Soledad (Universitat Autònoma de Barcelona) ;
Seoane Suárez, Joan (Institució Catalana de Recerca i Estudis Avançats)
The molecular characterisation of medulloblastoma, the most common paediatric brain tumour, is crucial for the correct management and treatment of this heterogenous disease. However, insufficient tissue sample, the presence of tumour heterogeneity, or disseminated disease can challenge its diagnosis and monitoring. [...]
2020 - 10.1038/s41467-020-19175-0
Nature communications, Vol. 11 (october 2020)
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