Results overview: Found 3 records in 0.02 seconds.
Articles, 3 records found
Articles 3 records found  
1.
18 p, 3.6 MB hnRNPDL phase separation is regulated by alternative splicing and disease-causing mutations accelerate its aggregation / Batlle Carreras, Cristina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Yang, Peiguo (St. Jude Children's Research Hospital. Department of Cell and Molecular Biology) ; Coughlin, Maura (St. Jude Children's Research Hospital. Department of Cell and Molecular Biology) ; Messing, James (Howard Hughes Medical Institute) ; Pesarrodona Roches, Mireia (Institut de Recerca Biomèdica) ; Szulc, Elzbieta (Institut de Recerca Biomèdica) ; Salvatella, Xavier (Institut de Recerca Biomèdica) ; Kim, Hong Joo (St. Jude Children's Research Hospital. Department of Cell and Molecular Biology) ; Taylor, J. Paul (Howard Hughes Medical Institute) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Prion-like proteins form multivalent assemblies and phase separate into membraneless organelles. Heterogeneous ribonucleoprotein D-like (hnRNPDL) is a RNA-processing prion-like protein with three alternative splicing (AS) isoforms, which lack none, one, or both of its two disordered domains. [...]
2020 - 10.1016/j.celrep.2019.12.080
Cell reports, Vol. 30, issue 4 (Jan. 2020) , p. 1117-1128  
2.
12 p, 3.6 MB ZPD-2, a small compound that inhibits α-synuclein amyloid aggregation and its seeded polymerization / Peña Díaz, Samuel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pujols, Jordi (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Conde Giménez, María (Universidad de Zaragoza. Instituto Universitario de Investigación de Biocomputación y Física de Sistemas Complejos) ; Čarija, Anita (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Dalfo, Esther (Universitat Autònoma de Medicina. Facultat de Medicina) ; García, Jesús (Institut de Recerca Biomèdica) ; Navarro Cantero, Susanna (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pinheiro, Francisca (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Santos Suárez, Jaime (Universitat Autonoma de Barcelona. Departament de Bioquimica i Biologia Molecular) ; Salvatella, Xavier (Institut de Recerca Biomèdica) ; Sancho, Javier (Universidad de Zaragoza. Instituto Universitario de Investigación de Biocomputación y Física de Sistemas Complejos) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
α-Synuclein (α-Syn) forms toxic intracellular protein inclusions and transmissible amyloid structures in Parkinson's disease (PD). Preventing α-Syn self-assembly has become one of the most promising approaches in the search for disease-modifying treatments for this neurodegenerative disorder. [...]
2019 - 10.3389/fnmol.2019.00306
Frontiers in molecular neuroscience, Vol. 12 (Dec. 2019) , art. 306  
3.
17 p, 4.2 MB RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation / Morales, Mònica (Institut de Recerca Biomèdica) ; Arenas, Enrique J (Institut de Recerca Biomèdica) ; Urosevic, Jelena (Institut de Recerca Biomèdica) ; Guiu, Marc (Institut de Recerca Biomèdica) ; Fernández, Esther (Institut de Recerca Biomèdica) ; Planet, Evarist (Institut de Recerca Biomèdica) ; Fenwick, Robert Bryn (Institut de Recerca Biomèdica) ; Fernández Ruiz, Sonia (CIC bioGUNE) ; Salvatella, Xavier (Institut de Recerca Biomèdica) ; Reverter i Cendrós, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carracedo, Arkaitz (CIC bioGUNE) ; Massagué, Joan (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Gomis, Roger R (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
In estrogen receptor-negative breast cancer patients, metastatic relapse usually occurs in the lung and is responsible for the fatal outcome of the disease. Thus, a better understanding of the biology of metastasis is needed. [...]
2014 - 10.15252/emmm.201303675
EMBO Molecular Medicine, Vol. 6, issue 7 (Jul. 2014) , p. 865-881  

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