Home > Search Results: Santos, Hugo M.
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Articles, 3 records found
Articles 3 records found  
1.
9 p, 2.9 MB Study and Preparation of Multifunctional Poly(L-Lysine)@Hyaluronic Acid Nanopolyplexes for the Effective Delivery of Tumor Suppressive MiR-34a into Triple-Negative Breast Cancer Cells / Djafari, Jamila (Nova University Lisbon. Chemistry Department) ; Fernández-Lodeiro, Javier (Proteomass Scientific Society) ; Santos, Hugo M. (Proteomass Scientific Society) ; Lorenzo Rivera, Julia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rodriguez-Calado, Sergi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bértolo, Emilia (Canterbury Christ Church University) ; Capelo-Martínez, José Luis (Proteomass Scientific Society) ; Lodeiro, Carlos (Proteomass Scientific Society)
Non-viral gene delivery using exogenous microRNAs is a potential strategy for fighting cancers with poor prognosis and which lack specific therapies, such as triple-negative breast cancer (TNBC). Herein we report the synthesis of six nontoxic electrostatic polymeric nanocapsules (P1 to P6) for microRNA delivery in TNBC cells. [...]
2020 - 10.3390/ma13235309
Materials, Vol. 13, Issue 23 (December 2020) , art. 5309  
Detailed record - Creative Commons
2.
34 p, 1.7 MB Sustainable synthesis of luminescent CdTe quantum dots coated with modified silica mesoporous nanoparticles : Towards new protein scavengers and smart drug delivery carriers / Oliveira, Elisabete (Proteomass Scientific Society) ; Santos, Hugo M. (Proteomass Scientific Society) ; Jorge, Susana (Proteomass Scientific Society) ; Rodríguez-González, Benito (Scientific and Technological Research Assistance Centre) ; Novio Vázquez, Fernando (Institut Català de Nanociència i Nanotecnologia) ; Lorenzo Rivera, Julia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ruiz-Molina, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Capelo-Martínez, José Luis (Proteomass Scientific Society) ; Lodeiro, Carlos (Proteomass Scientific Society)
The synthesis and full characterization of a family of sustainable luminescent nanoparticles, CdTeQDs@MNs, made of quantum dots coated by modified mesoporous silica nanoparticles is reported. The presence of the luminescent QDs allows the imaging of the nanoparticles during cell internalization, as well as the visualization of selective release of doxorubicin inside the cell (via pH stimuli). [...]
2019 - 10.1016/j.dyepig.2018.09.047
Dyes and pigments, Vol. 161 (February 2019) , p. 360-369  
Detailed record -
3.
11 p, 2.5 MB Synthesis of functionalized fluorescent silver nanoparticles and their toxicological effect in aquatic environments (Goldfish) and HEPG2 cells / Oliveira, Elisabete (Universidade Nova de Lisboa. Faculdade de Ciências e Tecnologia) ; Santos, Hugo M. (Universidade Nova de Lisboa. Faculdade de Ciências e Tecnologia) ; Garcia-Pardo, Javier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Diniz, Mário (Universidade Nova de Lisboa. Faculdade de Ciências e Tecnologia) ; Lorenzo Rivera, Julia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Rodríguez-González, Benito (Centro de Apoyo Científico y Tecnológico a la Investigación) ; Capelo-Martínez, José Luis (Universidade Nova de Lisboa. Faculdade de Ciências e Tecnologia) ; Lodeiro, Carlos (Universidade Nova de Lisboa. Faculdade de Ciências e Tecnologia)
Silver nanoparticles, AgNPs, are widely used in our daily life, mostly due to their antibacterial, antiviral, and antifungal properties. However, their potential toxicity remains unclear. In order to unravel this issue, emissive AgNPs were first synthetized using an inexpensive photochemical method, and then their permeation was assessed in vivo in goldfish and in vitro in human hepatoma cells (HepG2). [...]
2013 - 10.3389/fchem.2013.00029
Frontiers in chemistry, Vol. 1, art. 29 (Dec. 2013)  
Detailed record - Creative Commons

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