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1.
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12 p, 2.1 MB |
A fermented milk product containing B. lactis CNCM i-2494 improves the tolerance of a plant-based diet in patients with disorders of gut-brain interactions
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Le Nevé, Boris (Danone Nutricia Research) ;
Martinez-De la Torre, Adrian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tap, Julien (Danone Nutricia Research) ;
Nieto Ruiz, Adoración (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Derrien, Muriel (Danone Nutricia Research) ;
Cotillard, Aurélie (Danone Nutricia Research) ;
Faurie, Jean-Michel (Danone Nutricia Research) ;
Barba Orozco, Elizabeth (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mego Silva, Marianela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dornic, Quentin (Danone Nutricia Research) ;
Butler, John (Lawson Health Research Institute) ;
Merino, Xavi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lobo, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pinsach Batet, Ferran (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pozuelo, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santos, Javier (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Guarner, Francisco (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Azpiroz Vidaur, Fernando (Universitat Autònoma de Barcelona. Departament de Medicina)
Healthy, plant-based diets, rich in fermentable residues, may induce gas-related symptoms. The aim of this exploratory study was to assess the effects of a fermented milk product, containing probiotics, on the tolerance of a healthy diet in patients with disorders of gut-brain interactions (DGBI), complaining of excessive flatulence. [...]
2021 -  10.3390/nu13124542
Nutrients, Vol. 13 Núm. 12 (december 2021) , p. 4542
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2.
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8 p, 1.7 MB |
Blastocystis sp. Carriage and Irritable Bowel Syndrome : Is the Association Already Established?
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Salvador, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lobo, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Goterris, Lidia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santos, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Sulleiro, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bailo, Begoña (National Centre of Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain; (B.B.); (D.C.); (I.F.)) ;
Carmena, David (National Centre of Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain; (B.B.); (D.C.); (I.F.)) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bosch-Nicolau, Pau (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Espinosa-Pereiro, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fuentes, Isabel (National Centre of Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain; (B.B.); (D.C.); (I.F.)) ;
Molina, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The intestinal protist Blastocystis sp. is one of the most common intestinal parasites observed in humans, and has a worldwide distribution, being more prevalent in developing countries. Although this parasite has been described decades ago, the pathogenic potential it is still not understood completely. [...]
2021 - 10.3390/biology10040340
Biology, Vol. 10 (april 2021)
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3.
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7 p, 469.0 KB |
Epidemiological and clinical profile of adult patients with Blastocystis sp. infection in Barcelona, Spain
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Salvador, Fernando (Hospital Universitari Vall d'Hebron) ;
Sulleiro, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron) ;
Alonso Cotoner, Carmen (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Santos, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Fuentes, Isabel (Instituto de Salud Carlos III, National Centre of Microbiology, Madrid, Spain) ;
Molina Romero, Israel (Hospital Universitari Vall d'Hebron)
Blastocystis spp. are among the most frequently observed intestinal parasites in humans. Despite the discovery of Blastocystis approximately 100 years ago, limited information is available regarding its pathogenesis, genetic diversity, and available treatment options. [...]
2016 - 10.1186/s13071-016-1827-4
Parasites & vectors, Vol. 9 (october 2016)
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4.
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14 p, 3.4 MB |
miR-16 and miR-103 impact 5-HT receptor signalling and correlate with symptom profile in irritable bowel syndrome
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Wohlfarth, Carolin (University of Heidelberg) ;
Schmitteckert, Stefanie (University of Heidelberg) ;
Härtle, Janina D. (University of Heidelberg) ;
Houghton, Lesley A. (Mayo Clinic) ;
Dweep, Harsh (National Centre for Toxicological Research) ;
Fortea, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Assadi, Ghazaleh (Karolinska Institutet (Estocolm, Suècia)) ;
Braun, Alexander (University of Heidelberg) ;
Mederer, Tanja (University of Heidelberg) ;
Pöhner, Sarina (University of Heidelberg) ;
Becker, Philip P. (University of Heidelberg) ;
Fischer, Christine (University of Heidelberg) ;
Granzow, Martin (University of Heidelberg) ;
Mönnikes, Hubert (Martin-Luther-Hospital) ;
Mayer, Emeran A. (University of California) ;
Sayuk, Gregory (Washington University School of Medicine) ;
Boeckxstaens, Guy (University Hospitals Leuven (Bèlgica)) ;
Wouters, Mira M. (University Hospitals Leuven (Bèlgica)) ;
Simrén, Magnus (University of Gothenburg) ;
Lindberg, Greger (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Ohlsson, Bodil (Skåne University Hospital (Suècia)) ;
Schmidt, Peter Thelin (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Dlugosz, Aldona (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Agreus, Lars (Karolinska Institutet (Estocolm, Suècia)) ;
Andreasson, Anna (Stockholm University) ;
D'Amato, Mauro (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Burwinkel, Barbara (University of Heidelberg) ;
Bermejo, Justo Lorenzo (University of Heidelberg) ;
Röth, Ralph (University of Heidelberg) ;
Lasitschka, Felix (University of Heidelberg) ;
Vicario, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Metzger, Marco (Branch of the Fraunhofer Institute Interfacial Engineering and Biotechnology) ;
Santos, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rappold, Gudrun A. (University of Heidelberg) ;
Martinez, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Niesler, Beate (University of Heidelberg) ;
Universitat Autònoma de Barcelona
2017 - 10.1038/s41598-017-13982-0
Scientific reports (Nature Publishing Group), Vol. 7 (october 2017)
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5.
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23 p, 1.5 MB |
The Role of Purported Mucoprotectants in Dealing with Irritable Bowel Syndrome, Functional Diarrhea, and Other Chronic Diarrheal Disorders in Adults
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Alonso Cotoner, Carmen (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Abril-Gil, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mall, John-P. Ganda (Linköping University. Department of Biomedical and Clinical Sciences) ;
Expósito, Elba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
González-Castro, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lobo, Beatriz (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Santos, Javier (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Chronic diarrhea is a frequent presenting symptom, both in primary care medicine and in specialized gastroenterology units. It is estimated that more than 5% of the global population suffers from chronic diarrhea. [...]
2021 - 10.1007/s12325-021-01676-z
Advances in Therapy, march 2021, p. 1-23
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6.
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18 p, 1.5 MB |
Prevalence and Clinical Characteristics of SARS-CoV-2 Confirmed and Negative Kawasaki Disease Patients During the Pandemic in Spain
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Fernández-Cooke, Elisa (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ;
Grasa, Carlos D. (Hospital Universitario La Paz (Madrid)) ;
Domínguez-Rodríguez, Sara (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ;
Barrios Tascón, Ana (Hospital Universitario Infanta Sofía) ;
SánchezManubens, Judith (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Anton, Jordi (Hospital Sant Joan de Déu (Manresa)) ;
Mercader, Beatriz (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Villalobos, Enrique (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Camacho, Marisol (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Navarro Gómez, María Luisa (Hospital General Universitario Gregorio Marañón) ;
Oltra Benavent, Manuel (Hospital Universitari i Politècnic La Fe de València) ;
Giralt, Gemma (Hospital Universitari Vall d'Hebron) ;
Bustillo, Matilde (Hospital Universitario Miguel Servet (Saragossa)) ;
Bello Naranjo, Ana María (Department of Pediatrics, Hospital Universitario Materno-Infantil de Las Palmas de Gran Canaria) ;
Rocandio, Beatriz (Hospital Universitario de Donostia.(Sant Sebastià, País Basc)) ;
Rodríguez-González, Moisés (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ;
Núñez Cuadros, Esmeralda (Hospital Regional Universitario de Málaga) ;
Aracil Santos, Javier (Hospital Universitario La Paz (Madrid)) ;
Moreno, David (Hospital Regional Universitario de Málaga) ;
Calvo, Cristina (Hospital Universitario La Paz (Madrid)) ;
Universitat Autònoma de Barcelona
Introduction: COVID-19 has a less severe course in children. In April 2020, some children presented with signs of multisystem inflammation with clinical signs overlapping with Kawasaki disease (KD), most of them requiring admission to the pediatric intensive care unit (PICU). [...]
2021 - 10.3389/fped.2020.617039
Frontiers in Pediatrics, Vol. 8 (january 2021)
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7.
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14 p, 251.1 KB |
Cancer-Associated Thrombosis : Beyond Clinical Practice Guidelines-A Multidisciplinary (SEMI-SEOM-SETH) Expert Consensus
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Pachón, Vanessa (Hospital Universitario Ramón y Cajal (Madrid)) ;
Trujillo-Santos, Javier (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
Domènech, Pere (Hospital Universitari de Bellvitge) ;
Gallardo, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Font, Carmen (Hospital Clínic i Provincial de Barcelona) ;
González-Porras, José Ramón (Instituto de Investigación Biomédica de Salamanca) ;
Pérez-Segura, Pedro (Hospital Clínico San Carlos (Madrid)) ;
Maestre, Ana (Hospital General Universitario de Elche) ;
Mateo, José (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz Martin, Andrés (Hospital General Universitario Gregorio Marañón) ;
Peris, María Luisa (Consorci Hospitalari Provincial de Castelló) ;
Lecumberri, Ramón (Hematology Service, Clínica Universidad de Navarra, IDISNA, CIBER-CV, Pamplona, Spain) ;
Universitat Autònoma de Barcelona
Despite the growing interest and improved knowledge about venous thromboembolism in cancer patients in the last years, there are still many unsolved issues. Due to the limitations of the available literature, evidence-based clinical practice guidelines are not able to give solid recommendations for challenging scenarios often present in the setting of cancer-associated thrombosis (CAT). [...]
2018 - 10.1055/s-0038-1675577
TH Open: Companion Journal to Thrombosis and Haemostasis, Vol. 2 (november 2018) , p. e373-e386
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8.
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8 p, 284.1 KB |
Clinical Characteristics and Outcomes of Patients with Lung Cancer and Venous Thromboembolism
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Ruiz-Artacho, Pedro (Hospital Clínico San Carlos (Madrid)) ;
Trujillo-Santos, Javier (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
López-Jiménez, Luciano (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Font, Carme (Hospital Clínic i Provincial de Barcelona) ;
Díaz-Pedroche, María del Carmen (Hospital Universitario 12 de Octubre (Madrid)) ;
Sánchez Muñoz-Torrero, Juan Francisco (Hospital San Pedro de Alcántara) ;
Peris, María Luisa (CEU Cardenal Herrera University) ;
Skride, Andris (Paul Stradins Clinical University Hospital ( Letonia)) ;
Maestre, Ana (Hospital Universitario de Vinalopó) ;
Monreal, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background The natural history of patients with lung cancer and venous thromboembolism (VTE) has not been consistently evaluated. Methods We used the RIETE (Registro Informatizado Enfermedad TromboEmbólica) database to assess the clinical characteristics, time course, and outcomes during anticoagulation of lung cancer patients with acute, symptomatic VTE. [...]
2018 - 10.1055/s-0038-1656542
TH Open: Companion Journal to Thrombosis and Haemostasis, Vol. 2 (june 2018) , p. e210-e217
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9.
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8 p, 589.1 KB |
Natural history of patients with venous thromboembolism and hereditary hemorrhagic telangiectasia. Findings from the RIETE registry
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Riera-Mestre, Antoni (Hospital Universitari de Bellvitge) ;
Mora-Luján, José María (Hospital Universitari de Bellvitge) ;
Trujillo-Santos, Javier (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
Del Toro, Jorge (Hospital General Universitario Gregorio Marañón) ;
Nieto, José Antonio (Hospital General Virgen De La Luz, Cuenca) ;
Pedrajas, José María (Hospital Clínico San Carlos (Madrid)) ;
López-Reyes, Raquel (Hospital Universitari i Politècnic La Fe de València) ;
Soler, Silvia (Fundació Hospital d'Olot i Comarcal de la Garrotxa) ;
Ballaz, Aitor (Hospital de Galdakao (Usansolo, Biscaia)) ;
Cerdà, Pau (Hospital Universitari de Bellvitge) ;
Monreal, Manel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Background: Limited data exist about the clinical presentation, ideal therapy and outcomes of patients with hereditary hemorrhagic telangiectasia (HHT) who develop venous thromboembolism (VTE). Methods: We used the data in the RIETE Registry to assess the clinical characteristics, therapeutic approaches and clinical outcomes during the course of anticoagulant therapy in patients with HHT according to initial presentation as pulmonary embolism (PE) or deep venous thrombosis (DVT). [...]
2019 - 10.1186/s13023-019-1172-8
Orphanet Journal of Rare Diseases, Vol. 14 Núm. 1 (september 2019) , p. 196
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10.
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24 p, 1.4 MB |
Intestinal mucosal mast cells : key modulators of barrier function and homeostasis
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Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron) ;
Paracuellos, Irene (Hospital Universitari Vall d'Hebron) ;
González-Castro, Ana María (Hospital Universitari Vall d'Hebron) ;
Rodríguez-Urrutia, Amanda (Universitat Autònoma de Barcelona) ;
Rodríguez-Lagunas, María J. (Universitat de Barcelona) ;
Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron) ;
Santos, Javier (Hospital Universitari Vall d'Hebron) ;
Vicario Perez, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The gastrointestinal tract harbours the largest opulation of mast cells in the body; this highly specialised leukocyte cell type is able to adapt its phenotype and function to the microenvironment in which it resides. [...]
2019 - 10.3390/cells8020135
Cells, Vol. 8 (2019) , p. 1-24
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